Projects per year
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Active
Fundamental research on the impact of metformin on bulk and selective autophagy, such as mitophagy and lipophagy, in breast cancer cell lines
Kokabi, K. (PI)
3/1/25 → 12/31/27
Project: Government
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Nuclear forms of AXL and TYRO3 receptors in bladder cancer
Tulchinsky, E. (PI), Kriajevskaia, M. (Other Faculty/Researcher) & Bryan, R. T. (Other Faculty/Researcher)
2/4/25 → 12/31/27
Project: FDCRGP
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Analysis of the effect of drug resistance mutations within HIV-1 Pol epitopes on HLA-A*02-epitope binding and CD8+ T cell response
Abidi, S. H. H. (PI), Uetrecht, C. (Co-PI), Rowland-Jones, S. (Co-PI), Ali, S. (Other Faculty/Researcher), Nugmanova, Z. (Other Faculty/Researcher) & Ibrahim, M. A. A. (Other Faculty/Researcher)
2/4/25 → 12/31/27
Project: FDCRGP
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Identification of potential protein biomarkers in pediatric sepsis using High Performance Liquid Chromatography-Mass Spectrometry
Sazonov, V. (PI), Galiyeva (NUSOM), D. (Co-PI), Khvan, M. (Other Faculty/Researcher), Gaipov, A. (Other Faculty/Researcher), Makhammajanov, Z. (Other Faculty/Researcher) & Zhailauova, A. (Other participant)
2/4/25 → 12/31/27
Project: FDCRGP
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Antimicrobial Resistance Study in Kazakhstan: Community Antibiotic Consumption and Resistance Rates
Semenova, Y. (PI) & Aljofan, M. (Co-PI)
2/4/25 → 12/31/27
Project: FDCRGP
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AXL receptor in bladder cancer: on the crossroad between mechanotransduction and RTK signalling
Kriajevskaia, M. (PI), Pham, T. (Co-PI) & Berillo, D. (Co-PI)
1/1/25 → 12/31/27
Project: CRP
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Next-generation, whole genome sequencing-based analysis of Hepatitis C virus circulating variants, transmission dynamics, and drug resistance-associated substitutions in Kazakhstan
Abidi, S. H. H. (PI), Oshakbayev, K. (Co-PI), Abuova, G. (Co-PI), Vattipally, S. (Co-PI), Ferrand, R. (Co-PI), Ali, S. (Other Faculty/Researcher), Gaipov, A. (Other Faculty/Researcher) & Konysbekova, A. (Other Faculty/Researcher)
1/1/25 → 12/31/27
Project: CRP
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REGAIN-CP: Research and Evaluation of Robot-Assisted Interventions for Gait Stability and Balance in Neurological Conditions: Cerebral Palsy in Children (REGAIN-CP)
Jamwal, P. (PI), Sarria-Santamera, A. (Co-PI), Ozhikenov, K. (Co-PI) & Shakenov, M. (Co-PI)
1/1/25 → 12/31/27
Project: CRP
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AIoT-enhanced Health Monitoring and Rehabilitation Using Biocompatible Triboelectric Sensors
Kalimuldina, G. (PI), Kammakakam, I. (Co-PI), Salustri, A. (Co-PI), Buribayev, Z. (Co-PI), Yeshmukhametov, A. (Other Faculty/Researcher), Rakhmanov, Y. (Other Faculty/Researcher) & Tsuchiya , K. (Other Faculty/Researcher)
1/1/25 → 12/31/27
Project: CRP
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Investigating endoplasmic reticulum oxidoreductase 1 alpha and protein disulfide isomerase interface as a potential target for anticancer therapy
Aljofan, M. (PI), Gulyayev, A. (Co-PI), Nurkenov , O. A. (Co-PI), Koes, D. (Co-PI), Saktashev, B. (Other Faculty/Researcher) & Poon , I. (Other Faculty/Researcher)
1/1/25 → 12/31/27
Project: CRP
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Periostin in bladder cancer: EMT, metastatic potential and potential crosstalk with the TAM receptor signaling.
Riethmacher, D. (PI), Riethmacher, E. (Co-PI), Tulchinsky, E. (Other Faculty/Researcher), Gushchin, D. (Other Faculty/Researcher), Bryan, R. T. (Other Faculty/Researcher) & Ward, D. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: FDCRGP
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Search for new therapeutic targets in antitumor therapy for breast cancer by genome-wide screening using the CRISPR method
Lezina, L. (PI)
1/1/24 → 12/31/26
Project: Government
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TAM receptors in bladder cancer: prospective targets and liquid biomarkers
Tulchinsky, E. (PI)
1/1/24 → 12/31/26
Project: Government
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An AI-based Approach for Analyzing Electronic Medical Records: Prediction of Healthcare Outcomes and Drug Demand
Gaipov, A. (PI), Aljofan, M. (Other Faculty/Researcher), Zollanvari, A. (Co-PI), Şen , F. (Other Faculty/Researcher), Aimyshev, T. (Other Faculty/Researcher), Yerdessov, S. (Other Faculty/Researcher) & Zhakhina, G. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: FDCRGP
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Manipulating mitochondrial dynamics to shape metabolic responses as potential therapeutic vulnerabilities in colorectal cancer (CRC)
Burska, A. N. (PI)
1/1/24 → 12/31/26
Project: Government
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Development of rectal drug targeted delivery system for colorectal cancer therapy
Umbayev, B. (PI), Bulanin, D. (Co-PI), Mun, E. (Other Faculty/Researcher), Kaldybekov, D. (Co-PI), Safarova, Y. (Other Faculty/Researcher) & Batyrbekov, K. (Other participant)
1/1/24 → 12/31/26
Project: CRP
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Identification and validation of urinary protein biomarkers in glomerular and diabetic kidney diseases using High Performance Liquid Chromatography-Mass Spectrometry and Surface-Enhanced Raman Scattering Spectroscopy
Gaipov, A. (PI), Bukasov, R. (Co-PI), Turebekov, D. (Co-PI) & Atageldiyeva, K. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: CRP
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HP1-driven phase separation: liquid droplets or collapsed globules?
Singh, P. (PI)
1/1/24 → 12/31/26
Project: FDCRGP
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The role of Periostin in extracellular vesicles in bladder cancer: Applying an orthotopic murine model and gene editing.
Riethmacher, D. (PI)
1/1/24 → 12/31/26
Project: Government
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Ventriculo-arterial coupling in patients with end-stage renal disease on hemodyalisis: Intra-dialytic changes and prognostic value.
Salustri, A. (PI)
1/1/24 → 12/31/26
Project: Government
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Patient derived lung cancer explants as a platform for validation of the correlation between CD320 and mutant p53
Lezina, L. (PI), Barlev, N. (Other Faculty/Researcher) & Gushchin, D. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: FDCRGP
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Molecular mechanisms of solid cancer resistance to INFg/TNFa cytokines secreted by CAR-T cells
Barlev, N. (PI), Begimbetova, D. (Co-PI) & Makishev, A. (Co-PI)
1/1/24 → 12/31/26
Project: CRP
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«Targeted drug delivery to improve the results of complex treatment of liver failure in abdominal sepsis».
Gulyayev, A. (PI), Zhumadilov, Z. (Co-PI), Kozhakhmetov, S. (Co-PI), Berikkhanova, K. (Other Faculty/Researcher), Taǐgulov, E. A. (Other Faculty/Researcher), Daniyeva, N. (Other Faculty/Researcher), Zakirov, E. (Other Faculty/Researcher) & Sergazy, S. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: CRP
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AMR: Evidence-based practice and policy to improve antibiotic stewardship and reduce antimicrobial resistance in Central Asia
Semenova, Y. (PI), Lim, L. (Co-PI) & Makalkina, L. (Co-PI)
1/1/24 → 12/31/26
Project: CRP
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Application of Artificial Intelligence (AI) in Food Recognition: Creating the first Central Asia Food Scenes Dataset for delivering personalized nutrition and health promotion in Kazakhstan
Chan, M. Y. (PI) & Varol, H. A. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: FDCRGP
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Innovative Assessment of Solid Cancers Burden in Kazakhstan and Its 10-year Trend Using Big Healthcare Data and Forecasting Models
Gaipov, A. (PI), Semenova, Y. (Other Faculty/Researcher), Zollanvari, A. (Other Faculty/Researcher) & Kashkynbayev, A. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: Government
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Genetically engineered Microbiome as a new treatment option for Inflammatory bowel disease
Riethmacher, E. (PI)
1/1/24 → 12/31/26
Project: Government
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Extremophiles from Eurasia as a potential source for novel antimicrobial agents, sub-project: Screening and identification of antimicrobials
Kunz Halder, J. (Co-PI), Paloyan, A. (Co-PI) & Antranikian, G. (Co-PI)
1/1/24 → 12/31/25
Project: International
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3D-FOODPRINT: Characterizing Applications of Functional Protein-Based 3D Food Inks for Sustainable Resourcing in Agri-Food Systems with a Focus on Buckwheat Proteins
Talamona, D. (PI), Chan, M. Y. (Co-PI), Auyeskhan, U. (Postdoctoral scholar (PhD degree holder)) & HUANG, D. (Other participant)
1/1/24 → 12/31/26
Project: FDCRGP
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MoVE-Kaz for Molecular Virology/Epidemiology Training in Kazakhstan
Ali, S. (Co-PI)
1/1/24 → …
Project: International
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Construction of Kazakh Brain Atlas and its role in the improvement of AI-based diagnostics of Dementia and Alzheimer's disease.
Bolla, S. (PI), Sandygulova, A. (Other Faculty/Researcher), Almazan, J. (Other Faculty/Researcher), Abidi, S. H. H. (Other Faculty/Researcher), Jumadilova, D. (Other Faculty/Researcher) & Maharjan, S. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: FDCRGP
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AEI: An educational intervention for health professionals in the assessment and management of Autism patients in Kazakhstan
Foster, F. (PI), Stolyarova, V. (Other Faculty/Researcher) & Toleubekova, L. (Other Faculty/Researcher)
1/1/23 → 12/31/25
Project: FDCRGP
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In-depth epidemiology and modeling of the 10-year trends of cardiovascular diseases and their complications in Kazakhstan using aggregated big data from the Unified National Electronic Healthcare System
Gaipov, A. (PI), Salustri, A. (Other Faculty/Researcher), Sarria-Santamera, A. (Other Faculty/Researcher), Akbilgic, O. (Other Faculty/Researcher), Abbay, A. (Other Faculty/Researcher) & Zhakhina, G. (Other participant)
1/1/23 → 12/31/25
Project: FDCRGP
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AP19676488: Identification of new genetic variants associated with the development of diabetic kidney disease by whole exome sequencing
Sarria-Santamera, A. (PI), Atageldiyeva, K. (Other Faculty/Researcher), Gaipov, A. (Other Faculty/Researcher), Durmanova, A. (Other Faculty/Researcher), Taurbekova, B. (PhD student/Master degree holder), Sarsenov, R. (Other Faculty/Researcher), Fazli, S. (Other Faculty/Researcher), Ortega, M. A. (Other Faculty/Researcher) & Almawi, W. (Other Faculty/Researcher)
1/1/23 → 12/31/25
Project: Government
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PED-DNT/MICROBIOME: Combined analysis of double negative T cells and microbiome in pediatric patients with rheumatic and hematological disorders (PED-DNT/MICROBIOME).
Tanko, M. N. (PI), Mukusheva, Z. (Co-PI), Kozhakhmetov, S. (Co-PI), Rozenson, R. (Co-PI), Kushugulova, A. (Other Faculty/Researcher), Nurgaliev, D. (Other Faculty/Researcher), Tuleutayev, Y. (Other Faculty/Researcher), Dossybayeva, K. (Other participant), Akhmaltdinova, L. (Other Faculty/Researcher), Assylbekova, M. (Other Faculty/Researcher), Shaykyzada , K. (Other Faculty/Researcher), Kyzdarbekova , Z. (Other Faculty/Researcher), Umirbekova, B. (Other Faculty/Researcher), Morenko, M. (Other Faculty/Researcher), Shnaider , X. (Other Faculty/Researcher), Dudnik, O. (Other Faculty/Researcher), Abdukhakimova, D. (Other participant), Kovzel, E. (Other Faculty/Researcher), Galiyeva (NUSOM), D. (Other Faculty/Researcher) & Kunz Halder, J. (Other Faculty/Researcher)
1/1/23 → 12/31/25
Project: CRP
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Proteolytic processing of TAM receptors: implications for the biology of bladder cancer and use as urine biomarkers
Kriajevskaia, M. (PI), Tulchinsky, E. (Co-PI), Tanko, M. N. (Co-PI) & Shalekenov, S. B. (Co-PI)
1/1/23 → 12/31/25
Project: FDCRGP
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Dissecting Zeb1-mediated regulation of p53 during epithelial-mesenchymal transition (EMT) in cancer
Barlev, N. (PI) & Tulchinsky, E. (Co-PI)
1/1/23 → 12/31/25
Project: FDCRGP
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Regulation of cellular identity and plasticity by mammalian HP1 proteins
Singh, P. (PI)
1/1/23 → 12/31/25
Project: Government
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Development of a national clinical and genetic registry for the spectrum of Amyotrophic Lateral Sclerosis (ALS) / Frontotemporal Dementia (FTD) in the Republic of Kazakhstan
Riethmacher, D. (PI), Tokay, T. (Co-PI), Kondybayeva, A. (Co-PI) & Kuanova, L. (Other Faculty/Researcher)
1/1/23 → 12/31/25
Project: CRP
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Identification of Hotspots of Currently Emerging HIV Infections in Kazakhstan Using an Integrated Phylodynamic-Epidemiologic Approach
Ali, S. (PI), Begimbetova, D. (Co-PI) & Nugmanova, Z. (Co-PI)
1/1/23 → 12/31/25
Project: CRP
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BCaDNA: Building Capacity in aDNA Research at Nazarbayev University: A Case Study of Berel (Altay Mountains) and other Sites from the Iron Age to the Golden Horde
Schamiloglu, U. (PI), Singh, P. (Co-PI) & Samashev, Z. (Co-PI)
1/1/21 → 12/31/25
Project: CRP
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PC: Prerequisites for end-of-life care provision in the presence of the legally guaranteed right to palliative care in Kazakhstan
Crape, B. (PI), Toleubekova, L. (Other Faculty/Researcher) & Alibekova, R. (Other Faculty/Researcher)
1/1/21 → 12/31/25
Project: FDCRGP
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Infectious triggers of chronic autoimmunity in spondyloarthropathy (CITAS)
Kunz Halder, J. (PI), Kushugulova, A. (Co-PI), Ainabekova, B. (Co-PI), Adilbayeva, A. (Postdoctoral scholar (PhD degree holder)), Zhubanchaliyev, A. (Other Faculty/Researcher), Sharip, A. (Other Faculty/Researcher), Nurgaziyeva, A. (Other Faculty/Researcher), Meiramova, A. (Other Faculty/Researcher), Isilbayeva, A. (Other Faculty/Researcher), Beeton, C. (Other Faculty/Researcher), Forslund, S. (Other Faculty/Researcher) & Poddighe, D. (Other Faculty/Researcher)
1/1/21 → 12/31/25
Project: CRP
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Finished
Effectiveness of preloaded combination nicotine replacement therapy on smoking cessation of adult population in Kazakhstan- A randomized controlled trial
Purushothama, C. (PI), Crape, B. (Co-PI), Jaxybayeva, A. (Co-PI) & Stolyarova, V. (Other Faculty/Researcher)
1/1/22 → 6/25/24
Project: CRP
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AP14869730: Effect of intensive exercise training on cardiac mechanics in athletes: A noninvasive evaluation of intra-ventricular pressure gradients.
Salustri, A. (PI), Gaipov, A. (Co-PI), Jumadilova, D. (Other Faculty/Researcher), Rakhmanov, Y. (Other Faculty/Researcher), Khissamutdinov, N. (Other Faculty/Researcher), Bekbossynova, M. (Other Faculty/Researcher), Khamitova, Z. (Other Faculty/Researcher), Dautov, T. (Other Faculty/Researcher), Zhankorazova, A. (Other Faculty/Researcher), Toktarbay, B. (Other Faculty/Researcher), Zholshybek, N. (Other Faculty/Researcher) & Lim, N. (Other Faculty/Researcher)
1/1/22 → 12/31/24
Project: Government