School of Medicine

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Research Output 1983 2019

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1983
29 Citations (Scopus)

THE VISUALISATION OF TRACE AMOUNTS OF DIAMINOBENZIDINE (DAB) POLYMER BY A NOVEL GOLD‐SULPHIDE‐SILVER METHOD

Newman, G. R., Jasani, B. & Williams, E. D., 1983, In : Journal of Microscopy. 132, 2, p. RP1-RP2

Research output: Contribution to journalArticle

Gold
Polymers
silver sulfide
1987
208 Citations (Scopus)

MHC antigens in urine as olfactory recognition cues

Singh, P. B., Brown, R. E. & Roser, B., May 14 1987, In : Nature. 327, 6118, p. 161-4 4 p.

Research output: Contribution to journalArticle

Histocompatibility Antigens
Major Histocompatibility Complex
Cues
Alleles
Urine
129 Citations (Scopus)

The major histocompatibility complex and the chemosensory recognition of individuality in rats

Brown, R. E., Singh, P. B. & Roser, B., 1987, In : Physiology and Behavior. 40, 1, p. 65-73 9 p.

Research output: Contribution to journalArticle

Major Histocompatibility Complex
Individuality
Urine
Recognition (Psychology)
Cues
1989
23 Citations (Scopus)

A monoclonal antibody to a determinant of the rat T cell antigen receptor expressed by a minor subset of T cells

Kampinga, J., Kroese, F. G., Pol, G. H., Nieuwenhuis, P., Haag, F., Singh, P. B., Roser, B. & Aspinall, R., 1989, In : International Immunology. 1, 3, p. 289-95 7 p.

Research output: Contribution to journalArticle

T-Lymphocyte Subsets
T-Cell Antigen Receptor
Thymocytes
Monoclonal Antibodies
T-Lymphocytes
43 Citations (Scopus)

Class I and class II regions of the major histocompatibility complex both contribute to individual odors in congenic inbred strains of rats

Brown, R. E., Roser, B. & Singh, P. B., Sep 1989, In : Behavior Genetics. 19, 5, p. 659-74 16 p.

Research output: Contribution to journalArticle

Inbred Strains Rats
major histocompatibility complex
Major Histocompatibility Complex
odor
odors

Povyshenie aktivnosti estestvennykh killerov u krys s nedostatochnost'yu vitamina A

Translated title of the contribution: An increase in activity of natural killer cells in rats with vitamin A deficiencySaparov, A. S., Kon, I. I. & Sharmanov, A. T., Mar 1 1989, In : Voprosy Pitaniia. 2, p. 30-2 3 p.

Research output: Contribution to journalArticle

Vitamin A Deficiency
Vitamin A
Natural Killer Cells
Formulated Food
Uridine
1991
139 Citations (Scopus)

Abrogation of glucocorticoid-mediated inhibition of T cell proliferation by the synergistic action of IL-1, IL-6, and IFN-gamma.

Almawi, WY., Lipman, ML., Stevens, AC., Zanker, B., Hadro, ET. & Strom, TB., 1991, In : Journal of Immunology. 146, 10, p. 3523-3527 5 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Evidence that glucocorticosteroid-mediated immunosuppressive effects do not involve altering second messenger function.

ALMAwI, WAM. Y., Hadro, EDWARD. T. & Strom, TERRY. B., 1991, In : Transplantation. 52, 1, p. 133-140 8 p.

Research output: Contribution to journalArticle

1992
50 Citations (Scopus)

Cloning and expression of Drosophila HP1 homologs from a mealybug, Planococcus citri

Epstein, H., James, T. C. & Singh, P. B., Feb 1992, In : Journal of Cell Science. 101 ( Pt 2), p. 463-74 12 p.

Research output: Contribution to journalArticle

Drosophila
Organism Cloning
Chromosomes
Chromosomal Position Effects
Complementary DNA
16 Citations (Scopus)

Mapping of a mouse homolog of a heterochromatin protein gene the X chromosome

Hamvas, R. M., Reik, W., Gaunt, S. J., Brown, S. D. & Singh, P. B., 1992, In : Mammalian Genome. 2, 1, p. 72-5 4 p.

Research output: Contribution to journalArticle

Modifier Genes
X-Linked Genes
Heterochromatin
Drosophila
Chromosomal Position Effects
4 Citations (Scopus)

Mapping of two human homologs of a Drosophila heterochromatin protein gene to the X chromosome

Reik, W., Leversha, M. A., Waterfield, N. R. & Singh, P. B., 1992, In : Mammalian Genome. 3, 11, p. 650-2 3 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Suppression of T-lymphocyte proliferation by sulphonamide hydroxylamines

Rieder, M. J., Sisson, E., Bird, I. A. & Almawi, W. Y., 1992, In : International Journal of Immunopharmacology. 14, 7, p. 1175-1180 6 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)

The mouse has a Polycomb-like chromobox gene

Pearce, J. J., Singh, P. B. & Gaunt, S. J., Apr 1992, In : Development. 114, 4, p. 921-9 9 p.

Research output: Contribution to journalArticle

Genes
Proteins
Cyclin B
Heterochromatin
Homeobox Genes
1993
8 Citations (Scopus)

Chromosomal localization of human homologs of the Drosophila heterochromatin protein 1 (HP1) gene

Chevillard, C., Reik, W., McDermott, M., Fontes, M., Mattei, M. G. & Singh, P. B., 1993, In : Mammalian Genome. 4, 2, p. 124-6 3 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Immunohistochemically demonstrated metallothionein expression in malignant melanoma

Zelger, B., Hittmair, A., Schir, M., Ofner, C., Fritsch, P. O., Bocker, W., Jasani, B. & Schmid, K. W., 1993, In : Histopathology. 23, 3, p. 257-263 7 p.

Research output: Contribution to journalArticle

Metallothionein
Melanoma
Paraffin
Heavy Ions
Nevus

Immunosuppressive Drugs Acting Through Blockade of Cytokine Expression

Almawi, W. Y., Stevens, A. C. & Lipman, M. L., 1993, In : Clinical Applications of Cytokines: Role in Pathogenesis, Diagnosis, and Therapy. p. 269 1 p.

Research output: Contribution to journalArticle

Korelacija glikolizovanog hemoglobina i fruktozamina kod trudnica s dijabetesom melitusom.

Translated title of the contribution: Correlation of glycosylated hemoglobin and fructosamine in pregnant women with diabetes mellitusRosić, B., Jevremović, M., Milacić, D., Gligorović, S., Stojanov, M., Ljubić, A. & Terzić, M., Jan 1 1993, In : Srpski Arhiv Za Celokupno Lekarstvo. 121, 1-2, p. 17-19 3 p.

Research output: Contribution to journalArticle

Fructosamine
Glycosylated Hemoglobin A
Pregnant Women
Diabetes Mellitus
Glucose
6 Citations (Scopus)

Uticaj preeklampsije na funkciju tireoidne zlezde.

Translated title of the contribution: The effect of pre-eclampsia on thyroid gland functionVojvodić, L., Sulović, V., Pervulov, M., Milacić, D. & Terzić, M., Jan 1 1993, In : Srpski Arhiv Za Celokupno Lekarstvo. 121, 1-2, p. 4-7 4 p.

Research output: Contribution to journalArticle

Pre-Eclampsia
Thyroid Gland
Pregnant Women
Pregnancy
Third Pregnancy Trimester
1994
172 Citations (Scopus)

A mammalian homologue of Drosophila heterochromatin protein 1 (HP1) is a component of constitutive heterochromatin

Wreggett, K. A., Hill, F., James, P. S., Hutchings, A., Butcher, G. W. & Singh, P. B., 1994, In : Cytogenetic and Genome Research. 66, 2, p. 99-103 5 p.

Research output: Contribution to journalArticle

Heterochromatin
Monoclonal Antibodies
Proteins
Centromere
Conserved Sequence
5 Citations (Scopus)

Endotoxin in the peripheral blood during acute intestinal allograft rejection

Li, X-C., Zhong, R., Quan, D., Almawi, W., Jevnikar, A. & Grant, D., 1994, In : Transplant International. 7, 3, p. 223-226 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Immunostimuliruiushchee deĭstvie laktobakteriĭ na tsitotoksichnost' estestvennykh kletok killerov i produktsiiu interferona

Translated title of the contribution: The immunostimulating action of lactobacteria on the cytotoxicity of natural killer cells and interferon productionTsoĭ, I. G., Saparov, A. S., Timofeeva, I. K., Dzhumagulova, A. B., Bulegenova, M. G. & Seksenbaev, B. D., Nov 1 1994, In : Zhurnal mikrobiologii, epidemiologii, i immunobiologii. 6, p. 112-3 2 p.

Research output: Contribution to journalArticle

Transferrin intraamniotic antimicrobial properties investigation

Terzic, M. M., Jan 1 1994, In : Giornale di Malattie Infettive e Parassitarie. 46, 2, p. 114-116 3 p.

Research output: Contribution to journalArticle

Amniotic Fluid
Transferrin
Amniocentesis
Staphylococcus epidermidis
Pregnancy
103 Citations (Scopus)

Trends in the use of glucocorticoids in renal transplantation

HRICIK, DONALD. E., ALMAWI, WASSIM. Y. & STROM, TERRY. B., 1994, In : Transplantation. 57, 7, p. 979-989 11 p.

Research output: Contribution to journalArticle

1995
52 Citations (Scopus)

5-Aminosalicylic acid abrogates T-cell proliferation by blocking interleukin-2 production in peripheral blood mononuclear cells.

Stevens, C., Lipman, M., Fabry, S., Moscovitch-Lopatin, M., Almawi, W., Keresztes, S., Peppercorn, M. A. & Strom, T. B., 1995, In : Journal of Pharmacology and Experimental Therapeutics. 272, 1, p. 399-406 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Allogeneic lymphocyte proliferation stimulated by small intestine-derived epithelial cells.

Li, X-C., Almawi, W., Jevnikar, A., Tucker, J., Zhong, R. & Grant, D., 1995, In : Transplantation. 60, 1, p. 82-89 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cbx-rs2 (M31), a mouse homolog of the Drosophila Heterochromatin protein 1 gene, maps to distal chromosome 11 and is nonallelic to Om

Feil, R., Baldacci, P. A., Tarttelin, E., Rhodes, M., Singh, P. B. & Reik, W., Jul 1995, In : Mammalian Genome. 6, 7, p. 469-71 3 p.

Research output: Contribution to journalArticle

1996

Cytokine mRNA production is not inhibited by immunosuppressive concentrations of sulfonamide reactive metabolites

Hess, DA., Almawi, WY., Bird, IA. & Rieder, MJ., 1996, In : Clinical Pharmacology and Therapeutics. 59, 2, p. 161-161 1 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)
Euchromatin
Heterochromatin
Interphase
Monoclonal Antibodies
Proteins
26 Citations (Scopus)

Partial mediation of glucocorticoid antiproliferative effects by lipocortins.

Almawi, W. Y., Saouda, M. S., Stevens, A. C., Lipman, M. L., Barth, C. M. & Strom, T. B., 1996, In : Journal of Immunology. 157, 12, p. 5231-5239 9 p.

Research output: Contribution to journalArticle

238 Citations (Scopus)

Regulation of cytokine and cytokine receptor expression by glucocorticoids

Almawi, W. Y., Beyhum, H. N., Rahme, A. A. & Rieder, M. J., 1996, In : Journal of Leukocyte Biology. 60, 5, p. 563-572 10 p.

Research output: Contribution to journalArticle

Selective abrogation of FK-506 mediated anti-proliferative effects of IL-2 but not IL-7

Rieder, MJ., Almawi, WY., Hess, DA., Kaidbey, HH., Chudzik, DM. & Assi, JW., 1996, In : Clinical Pharmacology and Therapeutics. 59, 2, p. 162-162 1 p.

Research output: Contribution to journalArticle

Synergistic inhibition of T cell proliferation by reactive drug metabolites

HESS, DAVID., BIRD, INGRID., ALMAWI, WASSIM. & RIEDER, MICHAEL., 1996, In : British Journal of Clinical Pharmacology. 42, 5

Research output: Contribution to journalArticle

1997

Altered Cytokine Production Induced by Sulfamethoxazole Hydroxylamine: PI-1

Hess, D., Almawi, W., Puvanesasingham, R. & Rieder, M., 1997, In : Clinical Pharmacology and Therapeutics. 61, 2

Research output: Contribution to journalArticle

Association of Altered T Cell Immunity with IDDM. More than a cause and effect

Beyhum, HN., Azar, ST. & Almawi, WY., 1997, In : International Journal of Diabetes Mellitus. 5, p. 126-141 16 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

M33, a mammalian homologue of Drosophila Polycomb localises to euchromatin within interphase nuclei but is enriched within the centromeric heterochromatin of metaphase chromosomes

Wang, G., Horsley, D., Ma, A., Otte, A. P., Hutchings, A., Butcher, G. W. & Singh, P. B., 1997, In : Cytogenetic and Genome Research. 78, 1, p. 50-5 6 p.

Research output: Contribution to journalArticle

Pretreatment with Glucocorticoids Enhance T-Cell Activation and Cytokine Expression

Almawi, W. & Jaffal, N., 1997, In : Journal of Allergy and Clinical Immunology. 99, 1

Research output: Contribution to journalArticle

140 Citations (Scopus)

Structure of the chromatin binding (chromo) domain from mouse modifier protein 1

Ball, L. J., Murzina, N. V., Broadhurst, R. W., Raine, A. R., Archer, S. J., Stott, F. J., Murzin, A. G., Singh, P. B., Domaille, P. J. & Laue, E. D., May 1 1997, In : EMBO Journal. 16, 9, p. 2473-81 9 p.

Research output: Contribution to journalArticle

Chromatin
Proteins
Protein Interaction Domains and Motifs
DNA-Binding Proteins
Nuclear magnetic resonance spectroscopy
11 Citations (Scopus)

Suppression of pokeweed mitogen-driven human IgM and IgG responses by the hydroxylamine of sulfamethoxazole

Sisson, M. E., Rieder, M. J., Bird, I. A. & Almawi, W. Y., 1997, In : International Journal of Immunopharmacology. 19, 5, p. 299-304 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The hydroxylamine of sulfamethoxazole synergizes with FK506 and cyclosporin A, inhibiting T-cell proliferation

Hess, D. A., Bird, I. A., Almawi, W. Y. & Rieder, M. J., 1997, In : Journal of Pharmacology and Experimental Therapeutics. 281, 1, p. 540-548 9 p.

Research output: Contribution to journalArticle

1998
31 Citations (Scopus)

Multiplicity of glucocorticoid action in inhibiting allograft rejection

Almawi, W. Y., Hess, D. A. & Rieder, M. J., 1998, In : Cell Transplantation. 7, 6, p. 511-523 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Significance of enhanced cytokine receptor expression by glucocorticoids

Almawi, W. Y., Hess, D. A. & Rieder, M. J., 1998, In : Blood. 92, 10, p. 3979-3979 1 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

The fission yeast chromo domain encoding gene chp1(+) is required for chromosome segregation and shows a genetic interaction with alpha-tubulin

Doe, C. L., Wang, G., Chow, C., Fricker, M. D., Singh, P. B. & Mellor, E. J., Sep 15 1998, In : Nucleic Acids Research. 26, 18, p. 4222-9 8 p.

Research output: Contribution to journalArticle

Chromosome Segregation
Schizosaccharomyces
Centromere
Tubulin
Chromatin
10 Citations (Scopus)

The M31 gene has a complex developmentally regulated expression profile and may encode alternative protein products that possess diverse subcellular localisation patterns

Peterson, K., Wang, G., Horsley, D., Richardson, J. C., Sapienza, C., Latham, K. E. & Singh, P. B., Mar 1 1998, In : Journal of Experimental Zoology. 280, 4, p. 288-303 16 p.

Research output: Contribution to journalArticle

protein products
genes
centromeres
heterochromatin
chromosome segregation
1999
74 Citations (Scopus)

An alternate mechanism of glucocorticoid anti-proliferative effect: promotion of a Th2 cytokine-secreting profile

Almawi, WY., Melemedjian, OK. & Rieder, MJ., 1999, In : Clinical Transplantation. 13, 5, p. 365-374 10 p.

Research output: Contribution to journalArticle

367 Citations (Scopus)

Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31

Aagaard, L., Laible, G., Selenko, P., Schmid, M., Dorn, R., Schotta, G., Kuhfittig, S., Wolf, A., Lebersorger, A., Singh, P. B., Reuter, G. & Jenuwein, T., Apr 1 1999, In : EMBO Journal. 18, 7, p. 1923-38 16 p.

Research output: Contribution to journalArticle

Chromosomal Position Effects
Heterochromatin
Centromere
Drosophila
Chromatin
106 Citations (Scopus)

Heterochromatin protein 1 modifies mammalian PEV in a dose- and chromosomal-context-dependent manner

Festenstein, R., Sharghi-Namini, S., Fox, M., Roderick, K., Tolaini, M., Norton, T., Saveliev, A., Kioussis, D. & Singh, P., Dec 1999, In : Nature Genetics. 23, 4, p. 457-61 5 p.

Research output: Contribution to journalArticle

Chromosomal Position Effects
Transgenes
Locus Control Region
Transgenic Mice
Mammals
279 Citations (Scopus)

KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing

Ryan, R. F., Schultz, D. C., Ayyanathan, K., Singh, P. B., Friedman, J. R., Fredericks, W. J. & Rauscher, F. J., Jun 1999, In : Molecular and Cellular Biology. 19, 6, p. 4366-78 13 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Heterochromatin
Zinc Fingers
Gene Silencing
Genes
45 Citations (Scopus)

M31, a murine homolog of Drosophila HP1, is concentrated in the XY body during spermatogenesis

Motzkus, D., Singh, P. B. & Hoyer-Fender, S., 1999, In : Cytogenetic and Genome Research. 86, 1, p. 83-8 6 p.

Research output: Contribution to journalArticle

Sex Chromosomes
Spermatogenesis
Drosophila
Spermatocytes
Heterochromatin
11 Citations (Scopus)

Opposing effects of rapamycin and cyclosporin A on activation-induced Ca2+ release

Almawi, W. Y., Assi, J. W., Chudzik, D. M. & Lazarovits, A. I., 1999, In : European Journal of Pharmacology. 381, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle