School of Medicine

  • Kazakhstan

Research Output 1983 2020

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Article
2003

Prevalence of hepatitis C virus isolate genotypes from chronically infected Lebanese patients: a hospital-based study.

Irani-Hakime, N., Samaha, H., Almawi, W., Nasr, E., Mokhbat, J., Abou, M. J., Daccache, J. & Rahal, E., 2003, In : Journal Medical Libanais. 51, 3, p. 121-126 6 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Single-center experience with tacrolimus-based immunosuppressive regimens in renal transplantation

Abou-Jaoude, M. M. & Almawi, W. Y., 2003, In : Molecular Immunology. 39, 17-18, p. 1067-1072 6 p.

Research output: Contribution to journal › Article

4 Citations (Scopus)

Tacrolimus (FK506) versus cyclosporin a microemulsion (neoral) maintenance immunosuppression: effects on graft survival and function, infection, and metabolic profile following kidney transplantation (KT)

Abou-Jaoude, M. M., Ghantous, I. & Almawi, W. Y., 2003, In : Molecular Immunology. 39, 17-18, p. 1095-1100 6 p.

Research output: Contribution to journal › Article

287 Citations (Scopus)

Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa

Tamaru, H., Zhang, X., McMillen, D., Singh, P. B., Nakayama, J., Grewal, S. I., Allis, C. D., Cheng, X. & Selker, E. U., May 2003, In : Nature Genetics. 34, 1, p. 75-9 5 p.

Research output: Contribution to journal › Article

Neurospora crassa
DNA Methylation
Histones
Lysine
Methylation
2004
8 Citations (Scopus)

C677T and A1298C single nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene among Bahraini Arabs

Al-Habboubi, H. H., Tamim, H., Ameen, G. & Almawi, W. Y., 2004, In : Thrombosis and Haemostasis. 91, 04, p. 843-845 3 p.

Research output: Contribution to journal › Article

43 Citations (Scopus)

Components of a pathway maintaining histone modification and heterochromatin protein 1 binding at the pericentric heterochromatin in Mammalian cells

Xin, H., Yoon, H-G., Singh, P. B., Wong, J. & Qin, J., Mar 5 2004, In : Journal of Biological Chemistry. 279, 10, p. 9539-46 8 p.

Research output: Contribution to journal › Article

Histone Code
Heterochromatin
Protein Binding
Histones
Cells
32 Citations (Scopus)

Differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene among the Lebanese population

Almawi, W. Y., Finan, R. R., Tamim, H., Daccache, J. L. & Irani-Hakime, N., 2004, In : American Journal of Hematology. 76, 1, p. 85-87 3 p.

Research output: Contribution to journal › Article

211 Citations (Scopus)

Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana

Jackson, J. P., Johnson, L., Jasencakova, Z., Zhang, X., PerezBurgos, L., Singh, P. B., Cheng, X., Schubert, I., Jenuwein, T. & Jacobsen, S. E., Mar 2004, In : Chromosoma. 112, 6, p. 308-15 8 p.

Research output: Contribution to journal › Article

Gene Silencing
DNA Methylation
Arabidopsis
Histones
Lysine
55 Citations (Scopus)

Dynamic relocation of epigenetic chromatin markers reveals an active role of constitutive heterochromatin in the transition from proliferation to quiescence

Grigoryev, S. A., Nikitina, T., Pehrson, J. R., Singh, P. B. & Woodcock, C. L., Dec 1 2004, In : Journal of Cell Science. 117, Pt 25, p. 6153-62 10 p.

Research output: Contribution to journal › Article

Heterochromatin
Epigenomics
Chromatin
Lymphocytes
Histone Code
46 Citations (Scopus)

Factor V G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677T gene polymorphism in angiographically documented coronary artery disease

Almawi, W. Y., Ameen, G., Tamim, H., Finan, R. R. & Irani-Hakime, N., 2004, In : Journal of Thrombosis and Thrombolysis. 17, 3, p. 199-205 7 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations among patients with sickle cell disease in Eastern Saudi Arabia

Fawaz, N. A., Bashawery, L., Al-Sheikh, I., Qatari, A., Al-Othman, S. S. & Almawi, W. Y., 2004, In : American Journal of Hematology. 76, 3, p. 307-309 3 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)

Factor V Leiden, prothrombin G20210A and antibodies against phospholipids in recurrent spontaneous abortion

Mtiraoui, N., Borgi, L., Gris, J-C., Almawi, WY. & Mahjoub, T., 2004, In : Journal of Thrombosis and Haemostasis. 2, 8, p. 1482-1484 3 p.

Research output: Contribution to journal › Article

38 Citations (Scopus)

Hepatitis B and hepatitis C virus prevalence among dialysis patients in Bahrain and Saudi Arabia: a survey by serologic and molecular methods

Qadi, A. A., Tamim, H., Ameen, G., Bu-Ali, A., Al-Arrayed, S., Fawaz, N. A. & Almawi, W. Y., 2004, In : American Journal of Infection Control. 32, 8, p. 493-495 3 p.

Research output: Contribution to journal › Article

184 Citations (Scopus)

Heterochromatin and tri-methylated lysine 20 of histone H4 in animals

Kourmouli, N., Jeppesen, P., Mahadevhaiah, S., Burgoyne, P., Wu, R., Gilbert, D. M., Bongiorni, S., Prantera, G., Fanti, L., Pimpinelli, S., Shi, W., Fundele, R. & Singh, P. B., May 15 2004, In : Journal of Cell Science. 117, Pt 12, p. 2491-501 11 p.

Research output: Contribution to journal › Article

Heterochromatin
Histones
Lysine
Chromosomes
Polytene Chromosomes
18 Citations (Scopus)

Highly efficient mRNA-based gene transfer in feeder-free cultured H9 human embryonic stem cells

Ponsaerts, P., van der Sar, S., Van Tendeloo, V. F. I., Jorens, P. G., Berneman, Z. N. & Singh, P. B., 2004, In : Cellular Reprogramming. 6, 3, p. 211-6 6 p.

Research output: Contribution to journal › Article

Messenger RNA
Electroporation
Genes
Transgenes
Viruses

HLA class II profile and distribution of HLA-DRB1 and HLA-DQB1 alleles and haplotypes among Lebanese and Bahraini Arabs

Almawi, W. Y., Busson, M., Tamim, H., Al-Harbi, E. M., Finan, R. R., Wakim-Ghorayeb, S. F. & Motala, A. A., 2004, In : Clin. Diagn. Lab. Immunol.. 11, 4, p. 770-774 5 p.

Research output: Contribution to journal › Article

IMMUNE-MEDIATED RESPONSES AND DISORDERS-Specific HLA-DRB and-DQB Alleles and Haplotypes Confer Disease Susceptibility or Resistance in Bahraini Type 1 Diabetes Patients

Al-Harbi, E. M., Abbassi, A-J., Tamim, H., al-Jenaidi, F., Kooheji, M., Kamal, M., al-Mahroos, S., al-Nasir, F., Motala, A. A. & Almawi, W. Y., 2004, In : Clinical and Diagnostic Laboratory Immunology. 11, 2, p. 292-296 5 p.

Research output: Contribution to journal › Article

58 Citations (Scopus)

In vivo dynamics of Swi6 in yeast: evidence for a stochastic model of heterochromatin

Cheutin, T., Gorski, S. A., May, K. M., Singh, P. B. & Misteli, T., Apr 2004, In : Molecular and Cellular Biology. 24, 8, p. 3157-67 11 p.

Research output: Contribution to journal › Article

Heterochromatin
Yeasts
Schizosaccharomyces
Chromatin
Mammals
3 Citations (Scopus)

Is seroprevalence of HTLV-I/II among blood donors in Lebanon relevant?

Tamim, H., Musharrafieh, U., Ramia, S., Almawi, W. Y., Al-Jisr, T., Ayoub, T., Nabulsi-Majzoub, M., Kazma, H. & Baz, E. K., 2004, In : American Journal of Infection Control. 32, 4, p. 220-223 4 p.

Research output: Contribution to journal › Article

16 Citations (Scopus)

Messenger RNA electroporation is highly efficient in mouse embryonic stem cells: successful FLPe- and Cre-mediated recombination

Ponsaerts, P., Brown, J. P., Van den Plas, D., Van den Eeden, L., Van Bockstaele, D. R., Jorens, P. G., Van Tendeloo, V. F. I., Merregaert, J., Singh, P. B. & Berneman, Z. N., Nov 2004, In : Gene Therapy. 11, 21, p. 1606-10 5 p.

Research output: Contribution to journal › Article

Electroporation
Genetic Recombination
Embryonic Stem Cells
Messenger RNA
Transgenes
76 Citations (Scopus)

Mitotic phosphorylation of histone H3 at threonine 3

Polioudaki, H., Markaki, Y., Kourmouli, N., Dialynas, G., Theodoropoulos, P. A., Singh, P. B. & Georgatos, S. D., Feb 27 2004, In : FEBS Letters. 560, 1-3, p. 39-44 6 p.

Research output: Contribution to journal › Article

Phosphorylation
Nuclear Envelope
Threonine
Histones
Chromatin
22 Citations (Scopus)

NF-Y regulates the antisense promoter, bidirectional silencing, and differential epigenetic marks of the Kcnq1 imprinting control region

Pandey, R. R., Ceribelli, M., Singh, P. B., Ericsson, J., Mantovani, R. & Kanduri, C., Dec 10 2004, In : Journal of Biological Chemistry. 279, 50, p. 52685-93 9 p.

Research output: Contribution to journal › Article

Transcription
Epigenomics
Transcription Factors
Methylation
Binding Sites
43 Citations (Scopus)

On the link between Bcl-2 family proteins and glucocorticoid-induced apoptosis

Almawi, W. Y., Melemedjian, O. K. & Jaoude, M. M. A., 2004, In : Journal of Leukocyte Biology. 76, 1, p. 7-14 8 p.

Research output: Contribution to journal › Article

64 Citations (Scopus)

Outbreak of Burkholderia cepacia bacteremia traced to contaminated hospital water used for dilution of an alcohol skin antiseptic

Nasser, R. M., Rahi, A. C., Haddad, M. F., Daoud, Z., Irani-Hakime, N. & Almawi, W. Y., 2004, In : Infection Control and Hospital Epidemiology. 25, 3, p. 231-239 9 p.

Research output: Contribution to journal › Article

44 Citations (Scopus)

Prevalence of seromarkers of HBV and HCV among blood donors in eastern Saudi Arabia, 1998--2001

Bashawri, LAM., Fawaz, NA., Ahmad, MS., Qadi, AA. & Almawi, WY., 2004, In : International Journal of Laboratory Hematology. 26, 3, p. 225-228 4 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

Specific HLA-DRB and-DQB alleles and haplotypes confer disease susceptibility or resistance in Bahraini type 1 diabetes patients

Al-Harbi, E. M., Abbassi, A-J., Tamim, H., al-Jenaidi, F., Kooheji, M., Kamal, M., al-Mahroos, S., al-Nasir, F., Motala, A. A. & Almawi, W. Y., 2004, In : Clin. Diagn. Lab. Immunol.. 11, 2, p. 292-296 5 p.

Research output: Contribution to journal › Article

104 Citations (Scopus)

The inner nuclear membrane protein lamin B receptor forms distinct microdomains and links epigenetically marked chromatin to the nuclear envelope

Makatsori, D., Kourmouli, N., Polioudaki, H., Shultz, L. D., McLean, K., Theodoropoulos, P. A., Singh, P. B. & Georgatos, S. D., Jun 11 2004, In : Journal of Biological Chemistry. 279, 24, p. 25567-73 7 p.

Research output: Contribution to journal › Article

Heterochromatin
Nuclear Envelope
Nuclear Proteins
Oligomers
Histones
1 Citation (Scopus)

Thromboembolism and toxic shock syndrome: A case presentation and literature update

Musharrafieh, UM., Jamaleddine, GW., Taher, AT., Almawi, WY. & Tabbara, ZA., 2004, In : Journal of Thrombosis and Thrombolysis. 17, 2, p. 133-137 5 p.

Research output: Contribution to journal › Article

2005
44 Citations (Scopus)

A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis

Almawi, W. Y., Tamim, H., Kreidy, R., Timson, G., Rahal, E., Nabulsi, M., Finan, R. R. & Irani-Hakime, N., 2005, In : Journal of Thrombosis and Thrombolysis. 19, 3, p. 189-196 8 p.

Research output: Contribution to journal › Article

18 Citations (Scopus)

An Arab selective gradient in the distribution of factor V G1691A (Leiden), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T

Ameen, G., IRANI-HAKIME, N., Fawaz, NA., Mahjoub, T. & Almawi, W. Y., 2005, In : Journal of Thrombosis and Haemostasis. 3, 9, p. 2126-2127 2 p.

Research output: Contribution to journal › Article

21 Citations (Scopus)

Association between adverse pregnancy outcomes and maternal factor V G1691A (Leiden) and prothrombin G20210A genotypes in women with a history of recurrent idiopathic miscarriages

Mahjoub, T., Mtiraoui, N., Tamim, H., Hizem, S., Finan, R. R., Nsiri, B. & Almawi, W. Y., 2005, In : American Journal of Hematology. 80, 1, p. 12-19 8 p.

Research output: Contribution to journal › Article

CONTRIBUTION OF FACTOR V-LEIDEN, PROTHROMBIN G20210A, AND METHYLENETETRAHYDROFOLATE REDUCTASE C677T MUTATIONS TO THE GENETIC SUSCEPTIBILITY TO DEEP VENOUS THROMBOEMBOLISM

Almawi, W. Y., Tamim, H., Finan, R. R. & Irani-Hakime, N., Jun 2005, In : Journal of Thrombosis and Thrombolysis. 19, 3

Research output: Contribution to journal › Article

28 Citations (Scopus)

Contribution of selective HLA-DRB1/DQB1 alleles and haplotypes to the genetic susceptibility of type 1 diabetes among Lebanese and Bahraini Arabs

Al-Jenaidi, F. A., Wakim-Ghorayeb, S. F., Al-Abbasi, A., Arekat, M. R., Irani-Hakime, N., Najm, P., Al-Ola, K., Motala, A. A. & Almawi, W. Y., 2005, In : Journal of Clinical Endocrinology and Metabolism. 90, 9, p. 5104-5109 6 p.

Research output: Contribution to journal › Article

95 Citations (Scopus)

Differential subnuclear localization and replication timing of histone H3 lysine 9 methylation states

Wu, R., Terry, A. V., Singh, P. B. & Gilbert, D. M., Jun 2005, In : Molecular Biology of the Cell. 16, 6, p. 2872-81 10 p.

Research output: Contribution to journal › Article

Histone Code
Histones
Methylation
Lysine
Chromatin
48 Citations (Scopus)

Epigenetic regulation of mammalian pericentric heterochromatin in vivo by HP1

Kourmouli, N., Sun, Y., van der Sar, S., Singh, P. B. & Brown, J. P., Nov 25 2005, In : Biochemical and Biophysical Research Communications. 337, 3, p. 901-7 7 p.

Research output: Contribution to journal › Article

Histone Code
Heterochromatin
Epigenomics
Histones
Lysine
4 Citations (Scopus)

Factor V G1691A (Leiden) and prothrombin G20210A single-nucleotide polymorphisms in type 2 diabetes mellitus

Wakim-Ghorayeb, S. F., Keleshian, S. H., Timson, G., Finan, R. R., Najm, P., Irani-Hakime, N. & Almawi, W. Y., 2005, In : American Journal of Hematology. 80, 1, p. 84-86 3 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Low prevalence of antibodies to human T-lymphotropic virus-I/II among blood donors in eastern Saudi Arabia

Fawaz, N. A., Tamim, H. & Almawi, W. Y., 2005, In : American Journal of Infection Control. 33, 3, p. 189-191 3 p.

Research output: Contribution to journal › Article

2298 Citations (Scopus)

Molecular biology: The transcriptional landscape of the mammalian genome

FANTOM Consortium, Sep 2 2005, In : Science. 309, 5740, p. 1559-1563 5 p.

Research output: Contribution to journal › Article

Molecular Biology
Genome
Polyadenylation
Transcription Initiation Site
Transcriptome
34 Citations (Scopus)

Mutations in the heterochromatin protein 1 (HP1) hinge domain affect HP1 protein interactions and chromosomal distribution

Badugu, R., Yoo, Y., Singh, P. B. & Kellum, R., Feb 2005, In : Chromosoma. 113, 7, p. 370-84 15 p.

Research output: Contribution to journal › Article

Heterochromatin
Mutation
Proteins
Mutant Proteins
Origin Recognition Complex
29 Citations (Scopus)

Prevalence of antiphospholipid antibodies, factor V G1691A (Leiden) and prothrombin G20210A mutations in early and late recurrent pregnancy loss

Mtiraoui, N., Borgi, L., Hizem, S., Nsiri, B., Finan, R. R., Gris, J-C., Almawi, W. Y. & Mahjoub, T., 2005, In : European Journal of Obstetrics and Gynecology and Reproductive Biology. 119, 2, p. 164-170 7 p.

Research output: Contribution to journal › Article

14 Citations (Scopus)

Reduction in coagulation factor VII plasma levels by R353Q but not the- 323P0/10 promoter polymorphism in healthy Tunisians

Mtiraoui, N., Aboud, N., Bouraoui, H., Haizem, S., Gris, J. C., Busson, M., Tamim, H., Almawi, W. Y. & Mahjoub, T., 2005, In : American Journal of Hematology. 79, 1, p. 11-16 6 p.

Research output: Contribution to journal › Article

12 Citations (Scopus)

Susceptible and protective human leukocyte antigen class II alleles and haplotypes in Bahraini type 2 (non-insulin-dependent) diabetes mellitus patients

Motala, A. A., Busson, M., Al-Harbi, E. M., Khuzam, M. AA., Al-Omari, E. MD., Arekat, M. R. & Almawi, W. Y., 2005, In : Clin. Diagn. Lab. Immunol.. 12, 1, p. 213-217 5 p.

Research output: Contribution to journal › Article

10 Citations (Scopus)

Takayasu arteritis with high titre of antiphospholipid antibodies and MTHFR polymorphism

Al Jishi, A., Krishnan, P. R. & Almawi, W. Y., 2005, In : Journal of Thrombosis and Thrombolysis. 20, 1, p. 47-50 4 p.

Research output: Contribution to journal › Article

36 Citations (Scopus)

Varied prevalence of factor V G1691A (Leiden) and prothrombin G20210A single nucleotide polymorphisms among Arabs

Almawi, W. Y., Keleshian, S. H., Borgi, L., Fawaz, N. A., Abboud, N., Mtiraoui, N. & Mahjoub, T., 2005, In : Journal of Thrombosis and Thrombolysis. 20, 3, p. 163-168 6 p.

Research output: Contribution to journal › Article

2006
30 Citations (Scopus)

A case-control study on the association of idiopathic recurrent pregnancy loss with autoantibodies against $2-glycoprotein I and annexin V

Zammiti, W., Mtiraoui, N., Kallel, C., Mercier, E., Almawi, W. Y. & Mahjoub, T., 2006, In : Reproduction. 131, 4, p. 817-822 6 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Antibodies to $2-glycoprotein I and annexin V in women with early and late idiopathic recurrent spontaneous abortions

Zammiti, W., Mtiraoui, N., Hidar, S., Fekih, M., Almawi, WY. & Mahjoub, T., 2006, In : Archives of Gynecology and Obstetrics. 274, 5, p. 261-265 5 p.

Research output: Contribution to journal › Article

27 Citations (Scopus)

Association of-592C/A,-819C/T and-1082A/G interleukin-10 promoter polymorphisms with idiopathic recurrent spontaneous abortion

Zammiti, W., Mtiraoui, N., Cochery-Nouvellon, E., Mahjoub, T., Almawi, WY. & Gris, J-C., 2006, In : MHR: Basic science of reproductive medicine. 12, 12, p. 771-776 6 p.

Research output: Contribution to journal › Article

21 Citations (Scopus)

Association of factor V gene polymorphisms (Leiden; Cambridge; Hong Kong and HR2 haplotype) with recurrent idiopathic pregnancy loss in Tunisian women

Zammiti, W., Mtiraoui, N., Mercier, E., Abboud, N., Saidi, S., Mahjoub, T., Almawi, WY. & Gris, JC., 2006, In : Thrombosis and Haemostasis. 95, 4, p. 612-617 6 p.

Research output: Contribution to journal › Article

Association of Selective HLA class II Susceptible and Protective Haplotypes with Type 2 Diabetes in Bahrain and Lebanon

Almawi, W. Y., Wakim-Ghorayeb, S. F., Arekat, M. R., Najm, P., Keleshian, S. H., Al-Sayed, N., Blanchon, B., Samaha, H. R. & Irani-Hakime, N., 2006, In : Clinical and Vaccine Immunology.

Research output: Contribution to journal › Article

4 Citations (Scopus)

Association of the methylenetetrahydrofolate reductase A1298C but not the C677T single nucleotide polymorphism with sickle cell disease in Bahrain

Al-Absi, I. K., Al-Subaie, A. M., Ameen, G., Mahdi, N., Mohammad, A. M., Fawaz, N. A. & Almawi, W. Y., 2006, In : Hemoglobin. 30, 4, p. 449-453 5 p.

Research output: Contribution to journal › Article