Alexander Gulyayev, DSc,PhD, MD

Professor, Leading researcher

  • 490 Citations
  • 3 h-Index
1982 …2019
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Research Output 1982 2019

  • 490 Citations
  • 3 h-Index
  • 23 Article
  • 11 Chapter
  • 3 Review article
2019

Inhibition of α-Amylase and α-Glucosidase by New β-Aminopropionamidoxime Derivatives

Kayukova, L. A., Uzakova, A. B., Baitursynova, G. P., Dyusembaeva, G. T., Shul’gau, Z. T., Gulyayev, A. & Sergazy, S. D., May 5 2019, In : Pharmaceutical Chemistry Journal. 53, 2, p. 129-133 5 p.

Research output: Contribution to journalArticle

Glucosidases
Amylases
Hypoglycemic Agents
Oxadiazoles
Poisons

Пребиотические компоненты грудного молока и возможность повторения их эффектов в формулах детского питания

Translated title of the contribution: Prebiotic components of breast milk and the possibility of repeating their effects in infant formulasSkidan, I. N., Gulyayev, A. & Belmer, S. V., Jan 1 2019, In : Rossiyskiy Vestnik Perinatologii i Pediatrii. 64, 2, p. 37-50 14 p.

Research output: Contribution to journalArticle

Open Access
Prebiotics
Infant Formula
Human Milk
Food
Mucosal Immunity
2016
2 Citations (Scopus)

Cholesterol -An essential component of infant milk formulae?

Skidan, I. N., Kaznacheev, K. S. & Gulyaev, A. E., 2016, In : Voprosy Pitaniia. 85, 6, p. 118-130 13 p.

Research output: Contribution to journalReview article

Infant Formula
Human Milk
Milk
Cholesterol
Fats
1 Citation (Scopus)

Modern trends in study of polymorphism of genes encoding goat's milk proteins

Vorozhko, I. V., Skidan, I. N., Chernyak, O. O. & Gulyaev, A. E., 2016, In : Voprosy Pitaniia. 85, 5, p. 13-21 9 p.

Research output: Contribution to journalReview article

Milk Proteins
Goats
Milk
Genes
Functional Food
2015
3 Citations (Scopus)

Milk fat globules, as determinants of the nutritional and biological value of goat milk

Skidan, I. N., Gulyaev, A. E. & Kaznacheev, K. S., 2015, In : Voprosy Pitaniia. 84, 2, p. 81-95 15 p.

Research output: Contribution to journalArticle

Nutritive Value
Goats
Milk
Cytoplasmic Structures
Physiological Phenomena
2 Citations (Scopus)

The functional dietary components in infant formulas from goat milk

Skidan, I. N., Kaznacheev, K. S., Kirillova, A. V. & Gulyaev, A. E., Dec 1 2015, In : Voprosy Prakticheskoi Pediatrii. 10, 4, p. 38-48 11 p.

Research output: Contribution to journalReview article

Infant Formula
Goats
Milk
Child Development
Growth and Development
2014
2 Citations (Scopus)

Historical journey to infant feeding

Skidan, I. N., Gulyaev, A. E., Zelenkin, I. V. & Skidan, T. N., 2014, In : Voprosy Pitaniia. 83, 2, p. 68-72 5 p.

Research output: Contribution to journalArticle

Goats
Milk
Milk Substitutes
Human Milk
Child Development
8 Citations (Scopus)

Synthesis and intramolecular cyclization of N-acyl- and N-allyl-N'-(2-oxo-1,2-dihydro-pyridin-3-yl)thiourea

Kulakov, I. V., Nikitina, O. S., Fisyuk, A. S., Goncharov, D. S., Shul'Gau, Z. T. & Gulyaev, A. E., 2014, In : Chemistry of Heterocyclic Compounds. 50, 5, p. 670-676 7 p.

Research output: Contribution to journalArticle

Isothiocyanates
Thiourea
Cyclization
Derivatives
methacrylamide
2012

Cytisin amidophosphate - The new cytoprotector

Zhumadilov, Z., Nurgozhin, T., Gulyaev, A., Zhaugasheva, S., Gazaliyev, A., Ermekbayeva, B., Abuova, G. & Kenessary, A., Sep 2012, In : Hiroshima Journal of Medical Sciences. 61, 3, p. 45-49 5 p.

Research output: Contribution to journalArticle

Chemical and Drug Induced Liver Injury
Healthy Volunteers
Injections
Pharmaceutical Preparations
Therapeutics
2011

Method for determining cumulation factor in toxicological studies

Tritek, V. S. & Gulyaev, A. E., 2011, In : Eksperimental'naya i Klinicheskaya Farmakologiya. 74, 3, p. 35-36 2 p.

Research output: Contribution to journalArticle

Toxicology
Pharmaceutical Preparations
2007

Network copolymers of acrylic and methacrylic acids: Hydrophilic ointment bases for wound-healing preparations

Tazhbaev, E. M., Pak, R. N., Akhmetova, S. B., Burkeev, M. Z., Gulyaev, A. E. & Adekenov, S. M., Sep 2007, In : Pharmaceutical Chemistry Journal. 41, 9, p. 508-511 4 p.

Research output: Contribution to journalArticle

Ointment Bases
Wound Healing
Artemisia
Polymers
Oils
2005

Features of leucomisin pharmacokinetics in the blood serum upon itroduction by various methods

Aksartov, R. M., Gulyaev, A. E., Pak, R. N. & Adekenov, S. M., 2005, In : Eksperimental'naya i Klinicheskaya Farmakologiya. 68, 2, p. 44-46 3 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Blood
Sesquiterpenes
Lactones
Intraperitoneal Injections
2003
22 Citations (Scopus)

Enhanced antibacterial activity of rifampicin associated with biodegradable polybutylcyanoacrylate nanoparticles

Skidan, I. N., Gelperina, S. E., Severin, S. E. & Gulyaev, A. E., 2003, In : Antibiotiki i Khimioterapiya. 48, 1, p. 23-26 4 p.

Research output: Contribution to journalArticle

Rifampin
Nanoparticles
Macrophages
Pharmaceutical Preparations
Mycobacterium avium
1999
442 Citations (Scopus)

Significant transport of doxorubicin into the brain with polysorbate 80- coated nanoparticles

Gulyaev, A. E., Gelperina, S. E., Skidan, I. N., Antropov, A. S., Kivman, G. Y. & Kreuter, J., 1999, In : Pharmaceutical Research. 16, 10, p. 1564-1569 6 p.

Research output: Contribution to journalArticle

Polysorbates
Nanoparticles
Doxorubicin
Brain
Cyanoacrylates
1998

Antibacterial effect of antibiotics modified by their interaction with antitumor preparations on the cellular level

Gulyaev, A. E., Anisimova, E. V. & Kivman, G. Y., Apr 1998, In : Pharmaceutical Chemistry Journal. 32, 4, p. 186-188 3 p.

Research output: Contribution to journalArticle

Anti-Bacterial Agents
3 Citations (Scopus)

Nanoparticles as a vector for the directed delivery of antibiotics (a review)

Gulyaev, A. E., Ermekbaeva, B. A., Kivman, G. Y., Radchenko, T. G., Sherstov, A. Y. & Shirinskii, V. G., Mar 1998, In : Pharmaceutical Chemistry Journal. 32, 3, p. 115-118 4 p.

Research output: Contribution to journalArticle

Nanoparticles
Anti-Bacterial Agents
1997

System of selecting antibiotics against infection with intracellular localization of infecting agents

Anisimova, E. V., Gulyaev, A. E., Karlinskii, M. V. & Kivman, G. Y., Jan 1997, In : Pharmaceutical Chemistry Journal. 31, 1, p. 9-11 3 p.

Research output: Contribution to journalArticle

1994

Investigation of liposomes as agents for the supply of antibiotics to the intracellular medium of the organism and the focus of infectious inflammation

Gulyaev, A. E., Kivman, G. Y., Gubenko, L. V. & Ermekbaeva, B. A., Sep 1994, In : Pharmaceutical Chemistry Journal. 28, 9, p. 616-619 4 p.

Research output: Contribution to journalArticle

Liposomes
Anti-Bacterial Agents
Inflammation
1992
Pharmacokinetics
Bacteria
Pharmaceutical Preparations

Clinical pharmacokinetics of kanamycin in endolymphatic therapy of peritonitis

Lokhvitsky, S. V., Klepatsky, V. G., Gulyaev, A. E., Gaidukova, G. P. & Kivman Ya., G., 1992, In : Antibiotiki i Khimioterapiya. 37, 4, p. 34-36 3 p.

Research output: Contribution to journalArticle

Intralymphatic Injections
Omentum
Kanamycin
Ascitic Fluid
Peritoneum

Greater bioavailability of slightly soluble medicinals such as griseofulvin

Gaidukova, G. P., Gulyaev, A. E., Kivman, G. Y. & Munblit, V. Y., Feb 1992, In : Pharmaceutical Chemistry Journal. 26, 2, p. 121-123 3 p.

Research output: Contribution to journalArticle

Griseofulvin
Biological Availability
1991

Interaction of liposomal gentamicin with human peripheral blood leukocytes

Gubenko, L. V., Gulyaev, A. E., Kivman, G. Y., Nisnevich, M. M. & Trofimov, V. I., Oct 1991, In : Pharmaceutical Chemistry Journal. 25, 10, p. 693-695 3 p.

Research output: Contribution to journalArticle

Gentamicins
Leukocytes
1990

Antibiotic binding by leukocytes from brucellosis patients

Nigmatulin, A. Z., Gulyaev, A. E., Gubenko, L. V., Srymbetov, M. S. & Sharafutdinova, G. I., 1990, In : Antibiotiki i Khimioterapiya. 35, 9, p. 40-42 3 p.

Research output: Contribution to journalArticle

Methacycline
Brucellosis
Erythromycin
Rifampin
Gentamicins
1986

Cell pharmacokinetics and prediction of antibiotic activity in host cells: Comparative investigation of antibiotics active against P. aeruginosa

Kivman Ya., G., Gulyaev, A. E. & Nigmatulin, A. Z., 1986, Antibiotiki i Medicinskaya Biotechnologiya. 5 ed. Vol. 31. p. 366-369 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Protein Binding
Pseudomonas aeruginosa
Leukocytes
Pharmacokinetics
Cell Membrane
1985

Binding of certain antibiotics by subcellular fractions of rat liver homogenates and their intracellular distribution in acute radiation disease

Kivman Ya., G., Gulyaev, A. E. & Kulishov, V. A., 1985, Antibiotiki i Medicinskaya Biotechnologiya. 6 ed. Vol. 30. p. 438-441 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Subcellular Fractions
Acute Disease
Erythromycin
Radiation
Rifampin

Macrolide antibiotics: Characteristic features of interaction with organoids, intracellular distribution and sulfalen effect on it

Gulyaev, A. E. & Kivman Ya., G., 1985, Antibiotiki i Medicinskaya Biotechnologiya. 2 ed. Vol. 30. p. 103-106 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Oleandomycin
Organoids
Macrolides
Erythromycin
Anti-Bacterial Agents

Quantitative indices of gentamicin and sisomicin interaction with subcellular fractions of rat liver and kidneys and antibiotic intracellular distribution

Gulyaev, A. E. & Kivman, Y. G., 1985, Antibiotiki i Medicinskaya Biotechnologiya. 1 ed. Vol. 30. p. 50-54 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sisomicin
Organoids
Subcellular Fractions
Gentamicins
Anti-Bacterial Agents

Time-course of tetracycline sorption by alveolar macrophages of rabbits at early interaction stages

Kivman Ya., G., Nigmatulin, A. Z., Gulyaev, A. E. & Snegireva, N. S., 1985, Antibiotiki i Medicinskaya Biotechnologiya. 3 ed. Vol. 30. p. 197-200 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Methacycline
Pulmonary Alveoli
Tetracyclines
Alveolar Macrophages
Tetracycline
1984
Organoids
Pharmaceutical Preparations

A method of quantitative study of the intracellular distribution of drugs forming mobile complexes with organoids

Kivman, G. Y. & Gulyaev, A. E., Jul 1984, In : Pharmaceutical Chemistry Journal. 18, 7, p. 458-461 4 p.

Research output: Contribution to journalArticle

Organoids
Pharmaceutical Preparations
1 Citation (Scopus)

Binding and distribution of sulfanilamides in rat liver cells

Kivman Ya., G., Gulyaev, A. E. & Sariev, A. K., 1984, In : Farmakologiya i Toksikologiya. 47, 6, p. 71-74 4 p.

Research output: Contribution to journalArticle

Sulfanilamides
Organoids
Liver
Rats
Sulfamonomethoxine

Interaction of rifampicin with hepatocyte organoids of rats and its intracellular distribution

Gulyaev, A. E. & Kivman Ya., G., 1984, Antibiotiki. 11 ed. Vol. 29. p. 826-828 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Organoids
Subcellular Fractions
Liver Mitochondrion
Liver Microsomes
Rifampin

Penetration of some tetracyclines into leucocytes of human peripheral blood and their intracellular distribution

Kivman, G. Y., Gulyaev, A. E., Nigmatulin, A. Z. & Nadirova, B. A., 1984, Antibiotiki. 1 ed. Vol. 29. p. 35-39 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tetracyclines
Buffers
Neutrophils
Leukocytes
Lymphocytes
1983
2 Citations (Scopus)

Intracellular distribution of tetracyclines in hepatocytes of rats

Kivman Ya., G., Gulyaev, A. E. & Nadirova, B. A., 1983, Antibiotiki. 11 ed. Vol. 28. p. 834-837 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tetracyclines
Hepatocytes
Organoids
Cytoplasm
Pharmaceutical Preparations
1982
1 Citation (Scopus)

Age aspect and interaction of tetracyclines with subcellular fraction of rat liver homogenates

Gulyaev, A. E., Kivman Ya., G. & Nadirova, B. A., 1982, Antibiotiki. 10 ed. Vol. 27. p. 776-778 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Newborn Animals
Tetracyclines
Subcellular Fractions
Drug Interactions
Protein Binding
1 Citation (Scopus)

Interaction of tetracyclines with subcellular fractions of rat liver homogenates

Kivman Ya., G., Nadirova, B. A. & Gulyaev, A. E., 1982, Antibiotiki. 1 ed. Vol. 27. p. 45-48 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Drug Dose Response Relationship
Organoids
Tetracyclines
Subcellular Fractions
Drug Interactions

Organ and type factor in the phenomenon of interaction of tetracyclines with subcellular fractions of animals

Gulyaev, A. E., Nadirova, B. A. & Kivman Ya., G., 1982, Antibiotiki. 11 ed. Vol. 27. p. 840-842 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Species Specificity
Tetracyclines
Subcellular Fractions
Protein Binding
Myocardium