Darkhan Utepbergenov, PhD

Assistant Professor

  • 940 Citations
  • 15 h-Index
1994 …2022
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Fingerprint Dive into the research topics where Darkhan Utepbergenov is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Occludin Medicine & Life Sciences
Nitric Oxide Chemical Compounds
90-kDa Ribosomal Protein S6 Kinases Medicine & Life Sciences
Rats Chemical Compounds
Tight Junctions Medicine & Life Sciences
Zonula Occludens-1 Protein Medicine & Life Sciences
Phosphorylation Chemical Compounds
Tight Junction Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2017 2022

Saccule and Utricle
Cell Cycle
Hearing
Vertebrates
Transcription Factors
Post Translational Protein Processing
Parkinson Disease
Organized Financing
X Ray Crystallography
Mass Spectrometry
File
Nitrilotriacetic Acid
His-His-His-His-His-His
Proteins
Recombinant Proteins
Ownership

Research Output 1994 2019

  • 940 Citations
  • 15 h-Index
  • 29 Article
  • 1 Chapter
  • 1 Comment/debate

The apparent deglycase activity of DJ-1 results from the conversion of free methylglyoxal present in fast equilibrium with hemithioacetals and hemiaminals

Andreeva, A., Bekkhozhin, Z., Omertassova, N., Baizhumanov, T., Yeltay, G., Akhmetali, M., Toibazar, D. & Utepbergenov, D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 49, p. 18863-18872 10 p.

Research output: Contribution to journalArticle

Pyruvaldehyde
Sulfhydryl Compounds
Clustered Regularly Interspaced Short Palindromic Repeats
Decomposition
Personal Autonomy
3 Citations (Scopus)

A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1

Mussakhmetov, A., Shumilin, I. A., Nugmanova, R., Shabalin, I. G., Baizhumanov, T., Toibazar, D., Khassenov, B., Minor, W. & Utepbergenov, D., Sep 26 2018, In : Biochemical and Biophysical Research Communications. 504, 1, p. 328-333 6 p.

Research output: Contribution to journalArticle

Parkinsonian Disorders
Post Translational Protein Processing
Cysteine
Catalytic Domain
Sulfenic Acids
Kazakhstan
Parkinsonian Disorders
Post Translational Protein Processing
Biotechnology
Cysteine
6 Citations (Scopus)

Bacterial expression, purification and in Vitro phosphorylation of full-length ribosomal S6 kinase 2 (RSK2)

Utepbergenov, D., Hennig, P. M., Derewenda, U., Artamonov, M. V., Somlyo, A. V. & Derewenda, Z. S., Oct 1 2016, In : PLoS One. 11, 10, e0164343.

Research output: Contribution to journalArticle

Phosphorylation
Purification
phosphorylation
Ribosomal Protein S6 Kinases
phosphotransferases (kinases)
10 Citations (Scopus)

Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses

Baker, L. E., Ellena, J. F., Handing, K. B., Derewenda, U., Utepbergenov, D., Engel, D. A. & Derewenda, Z. S., Jan 1 2016, In : Acta Crystallographica Section D: Structural Biology. 72, 1, p. 49-58 10 p.

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
Nucleoproteins
Nucleocapsid
Proteins