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Eugene Tulchinsky, PhD

Professor

  • 3514 Citations
  • 31 h-Index
1985 …2022
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Fingerprint Dive into the research topics where Eugene Tulchinsky is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Epithelial-Mesenchymal Transition Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences
Neoplasm Metastasis Medicine & Life Sciences
Genetic Transcription Medicine & Life Sciences
Transcription Factor AP-1 Medicine & Life Sciences
Cultured Tumor Cells Medicine & Life Sciences
Neoplasm DNA Medicine & Life Sciences

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Projects 2020 2022

DNA Transposable Elements
Epithelial-Mesenchymal Transition
Neoplasm Genes
Gene Expression
Neoplasms

Research Output 1985 2019

  • 3514 Citations
  • 31 h-Index
  • 50 Article
  • 6 Review article
  • 2 Comment/debate
  • 1 Editorial
5 Citations (Scopus)

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

Li, N., Babaei-Jadidi, R., Lorenzi, F., Spencer-Dene, B., Clarke, P., Domingo, E., Tulchinsky, E., Vries, R. G. J., Kerr, D., Pan, Y., He, Y., Bates, D. O., Tomlinson, I., Clevers, H. & Nateri, A. S., Mar 1 2019, In : Oncogenesis. 8, 3, 13.

Research output: Contribution to journalArticle

Open Access
Tumor Microenvironment
Neoplastic Stem Cells
Colorectal Neoplasms
Drug Therapy
Neoplasms
11 Citations (Scopus)

EMT: A mechanism for escape from EGFR-targeted therapy in lung cancer

Tulchinsky, E., Demidov, O., Kriajevska, M., Barlev, N. A. & Imyanitov, E., Jan 2019, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1871, 1, p. 29-39 11 p.

Research output: Contribution to journalReview article

Epithelial-Mesenchymal Transition
Epidermal Growth Factor Receptor
Lung Neoplasms
Neoplasms
Non-Small Cell Lung Carcinoma

Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC

Sreekumar, R., Emaduddin, M., Al-Saihati, H., Moutasim, K., Chan, J., Spampinato, M., Bhome, R., Yuen, H. M., Mescoli, C., Vitale, A., Cillo, U., Rugge, M., Primrose, J., Hilal, M. A., Thirdborough, S., Tulchinsky, E., Thomas, G., Mirnezami, A. & Sayan, A. E., Oct 1 2019, In : Cell Death and Disease. 10, 10, 703.

Research output: Contribution to journalArticle

Open Access
Protein C Inhibitor
Protein Kinase Inhibitors
Liver Neoplasms
Protein Kinase C
Biomarkers
4 Citations (Scopus)

ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins

Al-Ismaeel, Q., Neal, C. P., Al-Mahmoodi, H., Almutairi, Z., Al-Shamarti, I., Straatman, K., Jaunbocus, N., Irvine, A., Issa, E., Moreman, C., Dennison, A. R., Emre Sayan, A., McDearmid, J., Greaves, P., Tulchinsky, E. & Kriajevska, M., Jul 2 2019, In : British Journal of Cancer. 121, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

Interleukin-11
S100 Proteins
Pancreatic Neoplasms
Interleukin-6
Epithelial-Mesenchymal Transition
1 Citation (Scopus)

Assessment of Nuclear ZEB2 as a Biomarker for Colorectal Cancer Outcome and TNM Risk Stratification

Sreekumar, R., Harris, S., Moutasim, K., DeMateos, R., Patel, A., Emo, K., White, S., Yagci, T., Tulchinsky, E., Thomas, G., Primrose, J. N., Sayan, A. E. & Mirnezami, A. H., Oct 5 2018, In : JAMA network open. 1, 6, p. e183115

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Biomarkers
Recurrence
Neoplasm Staging
Nomograms