Eva Riethmacher, PhD

Assistant professor

Calculated based on number of publications stored in Pure and citations from Scopus
1991 …2024

Research activity per year

Personal profile

Personal profile

Eve Riethmacher started her career working on signal transduction during development using mouse models. During her time as a postdoc, she continued to work on mouse models this time analyzing neuronal development and repair. During this time Dr.Riethmacher was already involved in the supervision of diploma and Ph.D. students. During the last years, Dr.Riethmacher has been working on cancer development and progression as well as inflammatory processes. Since coming to Nazarbayev University she is heavily involved in the supervision of MD students and master students during their research. She has held grants as PI and co-PI on colon cancer as well as co-PI on a grant working on inflammatory bowel disease and a grant on bladder cancer. Eva Riethmacher is also the program director at NUSOM for the Ph.D. program in Biomedical Sciences.

Professional Information

Since 02/2016 Assistant Professor at NU School of Medicine, KZ

2008-2016 Faculty of Medicine, University of Southampton, UK

1999-2008 Senior scientist at ZMNH, Hamburg, Germany

1995-1999 Postdoc at MDC, Berlin, Germany

1993-1995 Postdoc at MDL/MPI, Cologne, Germany

 

Research interests

  • Cancer development and progression
  • Inflammatory bowel disease
  • Mouse models in the development of disease

Publications

  1. Transient and locally restricted expression of the ros1 protooncogene during mouse development. Sonnenberg E, Gödecke A, Walter B, Bladt F, Birchmeier C. EMBO J. 1991 Dec;10(12):3693-702. 
  2. Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. Sonnenberg E, Meyer D, Weidner KM, Birchmeier C. J Cell Biol. 1993 Oct;123(1):223-35. 
  3. Tyrosine kinase receptors in the control of epithelial growth and morphogenesis during development. Birchmeier C, Sonnenberg E, Weidner KM, Walter B. Bioessays. 1993 Mar;15(3):185-90. 
  4. Expression of the met-receptor and its ligand, HGF-SF during mouse embryogenesis. Sonnenberg E, Weidner KM, Birchmeier C. EXS. 1993;65:381-94. 
  5. The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis. Sonnenberg-Riethmacher E, Walter B, Riethmacher D, Gödecke S, Birchmeier C.Genes Dev. 1996 May 15;10(10):1184-93 
  6. Isoform-specific expression and function of neuregulin. Meyer D, Yamaai T, Garratt A, Riethmacher-Sonnenberg E, Kane D, Theill LE, Birchmeier C. Development. 1997 Sep;124(18):3575-86. 
  7. Severe neuropathies in mice with targeted mutations in the ErbB3 receptor. Riethmacher D, Sonnenberg-Riethmacher E, Brinkmann V, Yamaai T, Lewin GR, Birchmeier C. Nature. 1997 Oct 16;389(6652):725-30. 
  8. The role of SF/HGF and c-Met in the development of skeletal muscle. Dietrich S, Abou-Rebyeh F, Brohmann H, Bladt F, Sonnenberg-Riethmacher E, Yamaai T, Lumsden A, Brand-Saberi B, Birchmeier C. Development. 1999 Apr;126(8):1621-9. 
  9. Infertile spermatozoa of c-ros tyrosine kinase receptor knockout mice show flagellar angulation and maturational defects in cell volume regulatory mechanisms. Yeung CH, Sonnenberg- Riethmacher E, Cooper TG. Biol Reprod. 1999 Oct;61(4):1062-9. 
  10. Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development. Woldeyesus MT, Britsch S, Riethmacher D, Xu L, Sonnenberg-Riethmacher E, Abou-Rebyeh F, Harvey R, Caroni P, Birchmeier C. Genes Dev. 1999 Oct 1;13(19):2538-48. 
  11. Receptor tyrosine kinase c-ros knockout mice as a model for the study of epididymal regulation of sperm function. Yeung CH, Sonnenberg-Riethmacher E, Cooper TG. J Reprod Fertil Suppl. 1998;53:137-47. 
  12. Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMa Schreiber, J., E. Riethmacher-Sonnenberg, D. Riethmacher (joint 1st authors), E. E. Tuerk, J. Enderich, M. R. Bosl, and M. Wegner Mol Cell Biol, 20(7), 2466-74 
  13. Development and degeneration of dorsal root ganglia in the absence of the HMG-domain transcription factor Sox10. Sonnenberg-Riethmacher E, Miehe M, Stolt CC, Goerich DE, Wegner M, Riethmacher D. Mech Dev. 2001 Dec;109(2):253-65. 
  14. An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus. Brockschnieder D, Pechmann Y, Sonnenberg-Riethmacher E, Riethmacher D. Genesis. 2006 Jul;44(7):322-7. 
  15. Maid (GCIP) is involved in cell cycle control of hepatocytes. Sonnenberg-Riethmacher E, Wüstefeld T, Miehe M, Trautwein C, Riethmacher D. Hepatology. 2007 Feb;45(2):404-11. 
  16. The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration. Malin D, Sonnenberg-Riethmacher E, Guseva D, Wagener R, Aszódi A, Irintchev A, Riethmacher D. J Cell Sci. 2009 Apr 1;122(Pt 7):995-1004. 
  17. Promotion of periostin expression contribute to the migration of Schwann cells. Sonnenberg- Riethmacher E., Miehe M.,Riethmacher D. J Cell Sci. 2015 Sep 1;128(17):3345-55 
  18. Coelho T, Sonnenberg-Riethmacher E, Gao Y, Mossotto E, Khojanazarov A, Griffin A, et al. Expression profile of the matricellular protein periostin in paediatric inflammatory bowel disease. Scientific Reports. 2021;11(1):6194.
  19. Sonnenberg-Riethmacher E, Miehe M, Riethmacher D. Periostin in Allergy and Inflammation. Front Immunol. 2021 Aug 27;12:722170. doi: 10.3389/fimmu.2021.722170. PMID: 34512647; PMCID: PMC8429843

Education/Academic qualification

PhD, University of Cologne

Award Date: Jun 1 1993

Diploma, University of Cologne

Award Date: Jun 1 1989

External positions

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