Jeanette Kunz, PhD

Associate Professor

  • 3327 Citations
  • 19 h-Index
1990 …2020
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Research Output 1990 2019

  • 3327 Citations
  • 19 h-Index
  • 25 Article
  • 1 Review article
2019
1 Citation (Scopus)

CTHRC1: A New Candidate Biomarker for Improved Rheumatoid Arthritis Diagnosis

Myngbay, A., Bexeitov, Y., Adilbayeva, A., Assylbekov, Z., Yevstratenko BP, Aitzhanova RM, Vyacheslav A. Adarichev, Matkarimov, B. & Kunz, J., Jun 12 2019, In : Frontiers in Immunology. 10, JUN, p. 1353 1353.

Research output: Contribution to journalArticle

Open Access
Rheumatoid Arthritis
Collagen
Biomarkers
Reactive Arthritis
Osteoarthritis
2016
17 Citations (Scopus)

Targeting Mechanotransduction at the Transcriptional Level: YAP and BRD4 Are Novel Therapeutic Targets for the Reversal of Liver Fibrosis

Zhubanchaliyev, A. & Kunz Halder, J., Dec 1 2016, In : Frontiers in Pharmacology. p. 762 11 p., PMC5131002.

Research output: Contribution to journalReview article

Hepatic Stellate Cells
Liver Cirrhosis
Proteins
Extracellular Matrix
Therapeutics
2010
43 Citations (Scopus)

Type I phosphatidylinositol phosphate kinase beta regulates focal adhesion disassembly by promoting β1 integrin endocytosis

Chao, W. T., Ashcroft, F., Daquinag, A. C., Vadakkan, T., Wei, Z., Zhang, P., Dickinson, M. E. & Kunz, J., 2010, In : Molecular and Cellular Biology. 30, 18, p. 4463-4479 17 p.

Research output: Contribution to journalArticle

Phosphatidylinositol Phosphates
Focal Adhesions
Endocytosis
Integrins
Phosphotransferases
29 Citations (Scopus)

Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation

Chao, W. T., Daquinag, A. C., Ashcroft, F. & Kunz, J., Jul 26 2010, In : Journal of Cell Biology. 190, 2, p. 247-262 16 p.

Research output: Contribution to journalArticle

Cell Movement
Cell Membrane
Integrins
Focal Adhesions
Phosphatidylinositols

Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation (The Journal of Cell Biology (2010) 190, 2, (247-262))

Chao, W. T., Daquinag, A. C., Ashcroft, F. & Kunz, J., Aug 9 2010, In : Journal of Cell Biology. 190, 3, p. 479 1 p.

Research output: Contribution to journalArticle

2009
123 Citations (Scopus)

Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins

Chao, W. T. & Kunz, J., Apr 17 2009, In : FEBS Letters. 583, 8, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Dynamin II
Vesicular Transport Adaptor Proteins
Clathrin
Focal Adhesions
Endocytosis
2007
52 Citations (Scopus)

16-kDa prolactin inhibits endothelial cell migration by down-regulating the Ras-Tiam1-Rac1-Pak1 signaling pathway

Lee, S. H., Kunz, J., Lin, S. H. & Yu-Lee, L. Y., Nov 15 2007, In : Cancer Research. 67, 22, p. 11045-11053 9 p.

Research output: Contribution to journalArticle

Prolactin
Cell Movement
Lymphoma
Phosphotransferases
Endothelial Cells
61 Citations (Scopus)

The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress

Daquinag, A., Fadri, M., Jung, S. Y., Qin, J. & Kunz, J., Jan 2007, In : Molecular and Cellular Biology. 27, 2, p. 633-650 18 p.

Research output: Contribution to journalArticle

Heat-Shock Response
Sphingolipids
Yeasts
Phosphorylation
Proteins
2005
369 Citations (Scopus)

Regulation of dendritic morphogenesis by Ras-PI3K-Akt-mTOR and Ras-MAPK signaling pathways

Kumar, V., Zhang, M. X., Swank, M. W., Kunz, J. & Wu, G. Y., Dec 7 2005, In : Journal of Neuroscience. 25, 49, p. 11288-11299 12 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Sirolimus
Dendrites
Morphogenesis
Dendritic Spines
96 Citations (Scopus)

The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5- bisphosphate and TORC2

Fadri, M., Daquinag, A., Wang, S., Xue, T. & Kunz, J., Apr 2005, In : Molecular Biology of the Cell. 16, 4, p. 1883-1900 18 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 4,5-Diphosphate
Phosphatidylinositols
Actin Cytoskeleton
Yeasts
Actins
217 Citations (Scopus)

The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila

Hiesinger, P. R., Fayyazuddin, A., Mehta, S. Q., Rosenmund, T., Schulze, K. L., Zhai, R. G., Verstreken, P., Cao, Y., Zhou, Y., Kunz, J. & Bellen, H. J., May 20 2005, In : Cell. 121, 4, p. 607-620 14 p.

Research output: Contribution to journalArticle

SNARE Proteins
Synaptic Vesicles
Exocytosis
Drosophila
Adenosine Triphosphatases
2002
61 Citations (Scopus)

Stereo-specific substrate recognition by phosphatidylinositol phosphate kinases is swapped by changing a single amino acid residue

Kunz, J., Fuelling, A., Kolbe, L. & Anderson, R. A., Feb 15 2002, In : Journal of Biological Chemistry. 277, 7, p. 5611-5619 9 p.

Research output: Contribution to journalArticle

Phosphatidylinositol Phosphates
Phosphotransferases
Amino Acids
Substrates
1-Phosphatidylinositol 4-Kinase
2001

Erratum: FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast (Molecular Microbiology (2001) 37:6 (1480-1493))

Kunz, J., Loeschman, A., Deuter-Reinhard, M. & Hall, M. N., 2001, In : Molecular Microbiology. 39, 4, p. 1107 1 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Protein 1A
Sirolimus
Microbiology
Transcription Factors
Yeasts
2000
14 Citations (Scopus)

FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast

Kunz, J., Loeschmann, A., Deuter-Reinhard, M. & Hall, M. N., 2000, In : Molecular Microbiology. 37, 6, p. 1480-1493 14 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Protein 1A
Sirolimus
Transcription Factors
Yeasts
Peptidylprolyl Isomerase
104 Citations (Scopus)

HEAT repeats mediate plasma membrane localization of Tor2p in yeast

Kunz, J., Schneider, U., Howald, I., Schmidt, A. & Hall, M. N., Nov 24 2000, In : Journal of Biological Chemistry. 275, 47, p. 37011-37020 10 p.

Research output: Contribution to journalArticle

Cell membranes
Yeast
Yeasts
Cell Membrane
Sirolimus
117 Citations (Scopus)

The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity

Kunz, J., Wilson, M. P., Kisseleva, M., Hurley, J. H., Majerus, P. W. & Anderson, R. A., Jan 2000, In : Molecular Cell. 5, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol Phosphates
Phosphotransferases
Phosphatidylinositols
Eukaryotic Cells
Catalytic Domain
1999
88 Citations (Scopus)

Coupled inositide phosphorylation and phospholipase D activation initiates clathrin-coat assembly on lysosomes

Arneson, L. S., Kunz, J., Anderson, R. A. & Traub, L. M., Jun 18 1999, In : Journal of Biological Chemistry. 274, 25, p. 17794-17805 12 p.

Research output: Contribution to journalArticle

Phospholipase D
Clathrin
Phosphorylation
Phosphatidylinositols
Lysosomes
231 Citations (Scopus)

Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes

Anderson, R. A., Boronenkov, I. V., Doughman, S. D., Kunz, J. & Loijens, J. C., Apr 9 1999, In : Journal of Biological Chemistry. 274, 15, p. 9907-9910 4 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 4,5-Diphosphate
Phosphatidylinositol 3-Kinase
Phosphatidylinositol Phosphates
1-Phosphatidylinositol 4-Kinase
Signal Transduction
1998
242 Citations (Scopus)

The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease

Schmidt, A., Beck, T., Koller, A., Kunz, J. & Hall, M. N., Dec 1 1998, In : EMBO Journal. 17, 23, p. 6924-6931 8 p.

Research output: Contribution to journalArticle

Sirolimus
Nutrients
Food
Growth
Starvation
1997

Phosphalidylinositol 4-phosphate 5-kinascs: A Novel Family

Anderson, R. A., Loiiens, J. C., Boronenkov, I. V., Parker, G. J., Kunz, J. & Lu, F., 1997, In : FASEB Journal. 11, 9

Research output: Contribution to journalArticle

phosphotransferases (kinases)
Phosphotransferases
Phosphates
phosphates
Phosphorylation
1996
194 Citations (Scopus)

TOR2 is required for organization of the actin cytoskeleton in yeast

Schmidt, A., Kunz, J. & Hall, M. N., Nov 26 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 24, p. 13780-13785 6 p.

Research output: Contribution to journalArticle

Actin Cytoskeleton
Yeasts
Phosphatidylinositols
Chaperonin Containing TCP-1
Phosphotransferases
1994
287 Citations (Scopus)

TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast

Helliwell, S. B., Wagner, P., Kunz, J., Deuter-Reinhard, M., Henriquez, R. & Hall, M. N., 1994, In : Molecular Biology of the Cell. 5, 1, p. 105-118 14 p.

Research output: Contribution to journalArticle

Sirolimus
Phosphatidylinositols
Phosphotransferases
Yeasts
G1 Phase Cell Cycle Checkpoints
1993
233 Citations (Scopus)

Cyclosporin A, FK506 and rapamycin: more than just immunosuppression

Kunz, J. & Hall, M. N., 1993, In : Trends in Biochemical Sciences. 18, 9, p. 334-338 5 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Tacrolimus
Sirolimus
Yeast
Immunosuppression
651 Citations (Scopus)

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

Kunz, J., Henriquez, R., Schneider, U., Deuter-Reinhard, M., Movva, N. R. & Hall, M. N., May 7 1993, In : Cell. 73, 3, p. 585-596 12 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Sirolimus
Phosphatidylinositols
Yeast
Signal transduction
83 Citations (Scopus)

The Immunosuppressant FK506 Inhibits Amino Acid Import in Saccharomyces cerevisiae

Heitman, J., Koller, A., Kunz, J., Henriquez, R., Schmidt, A., Movva, N. R. & Hall, M. N., Aug 1993, In : Molecular and Cellular Biology. 13, 8, p. 5010-5019 10 p.

Research output: Contribution to journalArticle

Tacrolimus
Immunosuppressive Agents
Saccharomyces cerevisiae
Amino Acids
Tacrolimus Binding Proteins
1990
14 Citations (Scopus)

Active transport of proteins into the nucleus

Wagner, P., Kunz, J., Koller, A. & Hall, M. N., Nov 26 1990, In : FEBS Letters. 275, 1-2, p. 1-5 5 p.

Research output: Contribution to journalArticle

Active Biological Transport
Nuclear Envelope
Nuclear Proteins
Carrier Proteins
Nuclear Pore