Projects per year
Personal profile
Personal profile
Dr.Kuralay Atageldiyeva, MD endocrinologist, has obtained her M.D. degree from Kazakh National Medical University (Almaty, Kazakhstan) and has completed doctorate course at the graduate school of Asahikawa Medical University (Japan) and was conferred Ph.D in Medicine in 2016. She had completed Residency Program in Endocrine Diseases at the Research Institute of Cardiology and Internal Diseases. Main clinical research focus in the Diabetic complications. Recipient of research support from Ministry of Health of the Republic of Kazakhstan for the project “Development of new molecular genetic methods for the pre-symptomatic diagnosis and treatment of a number of significant diseases” and from Ministry of Education and Sciences of the
Republic of Kazakhstan for the project “Development and Implementation of modern system of epidemiological monitoring of major chronic noncommunicable diseases” and owner of “Bolashak” International Scholarship of the first President of
Kazakhstan.
Research interests
1) Diabetic complications, pathophysiologic mechanisms and genetic predispositions; particularly in diabetic nephropathy
2) Obesity, underlying mechanisms and treatment options;
Publications
- K. Atageldiyeva, Y. Fujita , T. Yanagimachi, K.Mizumoto, Y.Takeda, J. Honjo, Y. Takiyama, A.Abiko, Y.Makino, M.Haneda., Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice, Plos One, June 21, 2016, http://dx.doi.org/10.1371/journal.pone.0157672
- Yanagimachi T, Fujita Y, Takeda Y, Honjo J, Atageldiyeva KK, Takiyama Y, Abiko A, Makino Y, Kieffer TJ, Haneda M. Pancreatic glucose-dependent insulinotropic polypeptide (GIP) (1-30) expression is upregulated in diabetes and PEGylated GIP(1-30) can suppress the progression of low-dose-STZ-induced hyperglycaemia in mice, Diabetologia. 2016 Mar; 59(3):533-41. doi: 10.1007/s00125-015-3842-y.
- H.Kitsunai, Y.Makino, H.Sakagami, K.Mizumoto, T.Yanagimachi, K.Atageldiyeva, Y.Takeda, Y.Fujita, A.Abiko, Y.Takiyama, M.Haneda, High glucose induces platelet‐derived growth factor‐C via carbohydrate response element‐binding protein in glomerular mesangial cells, Physiological Reports, Published 31 March 2016 Vol. 4 no. e12730 DOI: 10.14814/phy2.1273
- 4. KK Atageldiyeva, R Nemr, A Echtay, E Racoubian, S Sarray, WY Almawi; Apolipoprotein E genetic polymorphism influences the susceptibility to nephropathy in type 2 diabetes patients; Gene, Volume 715, 5 October 2019, 144011 https://doi.org/10.1016/j.gene.2019.144011
- Sarría-Santamera, A., Orazumbekova, B., Maulenkul, T., Gaipov, A. & Atageldiyeva, K.,The identification of diabetes mellitus subtypes applying cluster analysis techniques: A systematic review Dec 2 2020, In: International Journal of Environmental Research and Public Health. 17, 24, p. 1-27 27 p., 9523. https://doi.org/10.3390/ijerph17249523
- Fujita, Y., Atageldiyeva, K. K., Takeda, Y., Yanagimachi, T., Makino, Y. & Haneda, M., A Low-Carbohydrate Diet Improves Glucose Metabolism in Lean Insulinopenic Akita Mice Along With Sodium- Glucose Cotransporter 2 Inhibitor, Dec 11 2020, In: Frontiers in Endocrinology. 11, 601594.
https://doi.org/10.3389/fendo.2020.601594 - Alexander Nersesov, Arnur Gusmanov, Byron Crape, Gulnara Junusbekova, Salim Berkinbayev, Almagul Jumabayeva, Jamilya Kaibullayeva, Saltanat Madenova, Mariya Novitskaya, Margarita Nazarova, Abduzhappar Gaipov, Aiymkul Ashimkhanova, Kainar Kadyrzhanuly, Kuralay Atageldiyeva, Sandro Vento, Alpamys Issanov, Seroprevalence and risk factors for hepatitis B and hepatitis C in three large regions of
Kazakhstan, PLoS ONE, December 16, 2021, V16, Is12, e0261155, https://doi.org/10.1371/journal.pone.0261155 - Orazumbekova, B., Issanov, A., Atageldiyeva, K., Berkinbayev, S., Junusbekova, G., Danyarova, L., Shyman, Z., Tashmanova, A., & Sarria-Santamera, A. (2022). Prevalence of Impaired Fasting Glucose and Type 2 Diabetes in Kazakhstan: Findings From Large Study. Frontiers in public health, 10, 810153. https://doi.org/10.3389/fpubh.2022.81015
- Issanov, A., Gusmanov, A., Sakko, Y., Galiyeva, D., Alibekova, R., Kadyrzhanuly, K., Atageldiyeva, K., Myngbay, A., Askarov, M., Tuganbekova, S. and Crape, B., 2021. P. 109: Long Term Outcomes After Autologous Bone Marrow Stem Cell Treatment in Diabetes Mellitus: Data From Unified National Electronic Health System 2014–2019. Transplantation, 105(12S1), p.S40.
Teaching
Professional Development in higher Education:
- Professional Certificate in Academic Practice at Nazarbayev University, November 2018 - April 2019
- Nazarbayev University Faculty Program for Clerkship Development, April 2 -6, 2018 the University of Pittsburgh, USA
- Master Class in Clinical Teaching, June 3-7, 2019 the University of Pittsburgh, USA
External positions
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Collaborations and top research areas from the last five years
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Identification and validation of urinary protein biomarkers in glomerular and diabetic kidney diseases using High Performance Liquid Chromatography-Mass Spectrometry and Surface-Enhanced Raman Scattering Spectroscopy
Gaipov, A. (PI), Bukasov, R. (Co-PI), Turebekov, D. (Co-PI) & Atageldiyeva, K. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: CRP
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AP19676488: Identification of new genetic variants associated with the development of diabetic kidney disease by whole exome sequencing
Sarria-Santamera, A. (PI), Atageldiyeva, K. (Other Faculty/Researcher), Gaipov, A. (Other Faculty/Researcher), Durmanova, A. (Other Faculty/Researcher), Taurbekova, B. (PhD student/Master degree holder), Sarsenov, R. (Other Faculty/Researcher), Fazli, S. (Other Faculty/Researcher), Ortega, M. A. (Other Faculty/Researcher) & Almawi, W. (Other Faculty/Researcher)
1/1/23 → 12/31/25
Project: Government
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Identification of genes associated with recurrent pregnancy loss among Kazakhstani population
Atageldiyeva, K. (PI), Aimagambetova, G. (Co-PI), Ukybassova, T. (Other Faculty/Researcher), Babi, A. (Other Faculty/Researcher), Kanabekova, P. (Other Faculty/Researcher) & Kaldygulova, L. (Other Faculty/Researcher)
1/1/22 → 12/31/24
Project: Government
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АР13067915: Epidemiology of Non-Communicable Diseases in Children in Kazakhstan Using Big Healthcare Data and Innovative analytical approach
Galiyeva (NUSOM), D. (PI), Gusmanov, A. (Other Faculty/Researcher), Rakhimzhanova, M. (Other Faculty/Researcher), Atageldiyeva, K. (Other Faculty/Researcher), Sissoyev, D. (Other participant), Mussina, K. (Other participant) & Seikamzin, A. (Other participant)
1/1/22 → 12/31/24
Project: Government
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All-cause hospital admissions and incidence of type 2 diabetes among adolescents in Kazakhstan
Atageldiyeva, K., Syssoyev, D., Mussina, K., Poddighe, D., Gaipov, A. & Galiyeva, D., Dec 2025, In: Scientific Reports. 15, 1, 20746.Research output: Contribution to journal › Article › peer-review
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Cluster Analysis in Diabetes Research: A Systematic Review Enhanced by a Cross-Sectional Study
Taurbekova, B., Sarsenov, R., Yaqoob, M. M., Atageldiyeva, K., Semenova, Y., Fazli, S., Starodubov, A., Angalieva, A. & Sarria-Santamera, A., May 2025, In: Journal of Clinical Medicine. 14, 10, 3588.Research output: Contribution to journal › Review article › peer-review
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Genome-wide Association Studies of Diabetic Kidney Disease in East Asians With Type 2 Diabetes: Achievements and Future Perspectives
Taurbekova, B., Mukhtarova, K., Salpynov, Z., Almazan, J., Atageldiyeva, K. & Sarria-Santamera, A., 2025, (Accepted/In press) In: Current Medicinal Chemistry.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
PD-L1 gene variants as predictors of recurrent pregnancy loss: A case-control study among Kazakh women in Central and West Kazakhstan
Almawi, W. Y., Aimagambetova, G., Tursunov, A., Turesheva, A., Marat, A., Ilmaliyeva, A. & Atageldiyeva, K., Jun 2025, In: Journal of Reproductive Immunology. 169, 104524.Research output: Contribution to journal › Article › peer-review
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Comparison of diagnostic accuracy and acceptability of self-sampling devices for human Papillomavirus detection: A systematic review
Aimagambetova, G., Atageldiyeva, K., Marat, A., Suleimenova, A., Issa, T., Raman, S., Huang, T., Ashimkhanova, A., Aron, S., Dongo, A., Iztleuov, Y., Shamkeeva, S. & Azizan, A., Feb 2024, In: Preventive Medicine Reports. 38, 102590.Research output: Contribution to journal › Review article › peer-review
Open Access9 Citations (Scopus)