• 9216 Citations
  • 53 h-Index
1982 …2014

Research output per year

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Research Output

2012

Characterization of a novel oral glucocorticoid system and its possible role in disease

Cirillo, N., Hassona, Y., Pignatelli, M., Gasparoto, T. H., Morgan, D. J. & Prime, S. S., Jan 1 2012, In : Journal of Dental Research. 91, 1, p. 97-103 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Prevalence of different subtypes of serrated polyps and risk of synchronous advanced colorectal neoplasia in average-risk population undergoing first-time colonoscopy

Buda, A., De Bona, M., Dotti, I., Piselli, P., Zabeo, E., Barbazza, R., Bellumat, A., Valiante, F., Nardon, E., Probert, C. S., Pignatelli, M., Stanta, G., Sturniolo, G. C. & De Boni, M., Jun 11 2012, In : Clinical and Translational Gastroenterology. 3

Research output: Contribution to journalArticle

59 Citations (Scopus)

Regulatory function of trefoil peptides (TFF) on intestinal cell junctional complexes

Buda, A., Jepson, M. A. & Pignatelli, M., Oct 1 2012, In : Cell Communication and Adhesion. 19, 5-6, p. 63-68 6 p.

Research output: Contribution to journalReview article

21 Citations (Scopus)
2011

E-cadherin and the cytoskeletal network in colorectal cancer development and metastasis

Buda, A. & Pignatelli, M., Dec 1 2011, In : Cell Communication and Adhesion. 18, 6, p. 133-143 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
1 Citation (Scopus)

The actin-bundling protein Fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair

Qualtrough, D., Smallwood, K., Littlejohns, D. & Pignatelli, M., Feb 23 2011, In : BMC Gastroenterology. 11, 14.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2010

Role of human tissue kallikrein in gastrointestinal stromal tumour invasion

Dominek, P., Campagnolo, P., H-Zadeh, M., Kränkel, N., Chilosi, M., Sharman, J. A., Caporali, A., Mangialardi, G., Spinetti, G., Emanueli, C., Pignatelli, M. & Madeddu, P., Oct 26 2010, In : British journal of cancer. 103, 9, p. 1422-1431 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2009

The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro

Qualtrough, D., Singh, K., Banu, N., Paraskeva, C. & Pignatelli, M., Sep 9 2009, In : British journal of cancer. 101, 7, p. 1124-1129 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The Molecular Pathology of Sporadic and Hereditary Colorectal Cancer

Pignatelli, M., Banu, N. & Melegh, Z., Jan 14 2009, Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach. Blackwell Publishing Ltd., p. 305-316 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2007

Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: Possibilities for combination therapy

Banu, N., Buda, A., Chell, S., Elder, D., Moorghen, M., Paraskeva, C., Qualtrough, D. & Pignatelli, M., Oct 1 2007, In : Cell Proliferation. 40, 5, p. 768-779 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2006

Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations

Carvajal-Carmona, L. G., Alam, N. A., Pollard, P. J., Jones, A. M., Barclay, E., Wortham, N., Pignatelli, M., Freeman, A., Pomplun, S., Ellis, I., Poulsom, R., El-Bahrawy, M. A., Berney, D. M. & Tomlinson, I. P. M., Jan 1 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 8, p. 3071-3075 5 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Soluble IGF2 receptor rescues ApcMin/+ intestinal adenoma progression induced by Igf2 loss of imprinting

Harper, J., Burns, J. L., Foulstone, E. J., Pignatelli, M., Zaina, S. & Hassan, A. B., Feb 15 2006, In : Cancer Research. 66, 4, p. 1940-1948 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2005

Activated Akt expression in breast cancer: Correlation with p53, Hdm2 and patient outcome

Vestey, S. B., Sen, C., Calder, C. J., Perks, C. M., Pignatelli, M. & Winters, Z. E., May 2005, In : European Journal of Cancer. 41, 7, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
22 Citations (Scopus)

Laryngeal epithelial defenses against laryngopharyngeal reflux: Investigations of E-cadherin, carbonic anhydrase isoenzyme III, and pepsin

Gill, G. A., Johnston, N., Buda, A., Pignatelli, M., Pearson, J., Dettmar, P. W. & Koufman, J., Dec 2005, In : Annals of Otology, Rhinology and Laryngology. 114, 12 I, p. 913-921 9 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Reduced p120ctn expression correlates with poor survival in patients with adenocarcinoma of the gastroesophageal junction

Wijnhoven, B. P. L., Pignatelli, M., Dinjens, W. N. M. & Tilanus, H. W., Nov 1 2005, In : Journal of Surgical Oncology. 92, 2, p. 116-123 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2004

A Multicenter Phase I Gene Therapy Clinical Trial Involving Intraperitoneal Administration of E1A-Lipid Complex in Patients with Recurrent Epithelial Ovarian Cancer Overexpressing HER-2/neu Oncogene

Madhusudan, S., Tamir, A., Bates, N., Flanagan, E., Gore, M. E., Barton, D. P. J., Harper, P., Seckl, M., Thomas, H., Lemoine, N. R., Charnock, M., Habib, N. A., Lechler, R., Nicholls, J., Pignatelli, M. & Ganesan, T. S., May 1 2004, In : Clinical Cancer Research. 10, 9, p. 2986-2996 11 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Biochemical analysis and subcellular distribution of E-cadherin-catenin in adenocarcinomas of the gastro-oesophageal junction

Wijnhoven, B. P. L., Tucker, E. T., Dinjens, W. N. M., Tilanus, H. W. & Pignatelli, M., May 1 2004, In : Anticancer Research. 24, 3 A, p. 1369-1375 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Cytoskeletal network in colon cancer: From genes to clinical application

Buda, A. & Pignatelli, M., May 2004, In : International Journal of Biochemistry and Cell Biology. 36, 5, p. 759-765 7 p.

Research output: Contribution to journalShort survey

48 Citations (Scopus)

p14ARF expression in invasive breast cancers and ductal carcinoma in situ- relationships to p53 and Hdm2

Vestey, S. B., Sen, C., Calder, C. J., Perks, C. M., Pignatelli, M. & Winters, Z. E., Jul 29 2004, In : Breast Cancer Research. 6, 5, R571.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)
2003

Abnormalities of the cadherin-catenin complex in chemically-induced colo-rectal carcinogenesis

Tucker, E., Buda, A., Janghra, N., Baker, J., Coad, J., Moorghan, M., Havler, M., Dettmar, P. & Pignatelli, M., Feb 1 2003, In : Proceedings of the Nutrition Society. 62, 1, p. 229-236 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Butyrate downregulates α2β1 integrin: A possible role in the induction of apoptosis in colorectal cancer cell lines

Buda, A., Qualtrough, D., Jepson, M. A., Martines, D., Paraskeva, C. & Pignatelli, M., May 1 2003, In : Gut. 52, 5, p. 729-734 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Cell biology of laryngeal epithelial defenses in health and disease: Further studies

Bulmer, D., Ross, P. E., Axford, S. E., Johnston, N., Gill, G. A., Pearson, J. P., Dettmar, P. W., Panetti, M., Pignatelli, M. & Koufman, J. A., Jun 1 2003, In : Annals of Otology, Rhinology and Laryngology. 112, 6, p. 481-491 11 p.

Research output: Contribution to journalArticle

137 Citations (Scopus)

Erratum: Abnormalities of the cadherin-catenin complex in chemically-induced colo-rectal carcinogenesis (Proceedings of the Nutrition Society (2003) 62:1 (230-231))

Tucker, E., Buda, A., Janghra, N., Baker, J., Coad, J., Moorghan, M., Halver, M., Dettmar, P. & Pignatelli, M., May 1 2003, In : Proceedings of the Nutrition Society. 62, 2, 1 p.

Research output: Contribution to journalComment/debate

Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro

Jawhari, A. U., Buda, A., Jenkins, M., Shehzad, K., Sarraf, C., Noda, M., Farthing, M. J. G., Pignatelli, M. & Adams, J. C., Jan 1 2003, In : American Journal of Pathology. 162, 1, p. 69-80 12 p.

Research output: Contribution to journalArticle

174 Citations (Scopus)
2002

Abnormal immunoreactivity of the E-cadherin/catenin (α-, β-, and γ-) complex in premalignant and malignant non-melanocytic skin tumours

Papadavid, E., Pignatelli, M., Zakynthinos, S., Krausz, T. & Chu, A. C., Feb 11 2002, In : Journal of Pathology. 196, 2, p. 154-162 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abnormal α-catenin expression in invasive breast cancer correlates with poor patient survival

Nakopoulou, L., Gakiopoulou-Givalou, H., Karayiannakis, A. J., Giannopoulou, I., Keramopoulos, A., Davaris, P. & Pignatelli, M., Jun 22 2002, In : Histopathology. 40, 6, p. 536-546 11 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Genetics - Cellular basis

Buda, A. & Pignatelli, M., Nov 10 2002, In : British Medical Bulletin. 64, p. 45-58 14 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Molecular histology in the study of solid tumours

Campbell, R. J. & Pignatelli, M., Apr 20 2002, In : Journal of Clinical Pathology - Molecular Pathology. 55, 2, p. 80-82 3 p.

Research output: Contribution to journalShort survey

19 Citations (Scopus)

β-catenin - A linchpin in colorectal carcinogenesis?

Wong, N. A. C. S. & Pignatelli, M., Jan 1 2002, In : American Journal of Pathology. 160, 2, p. 389-401 13 p.

Research output: Contribution to journalReview article

312 Citations (Scopus)

β-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis

Hao, X., Frayling, I. M., Willcocks, T. C., Han, W., Tomlinson, I. P., Pignatelli, M. N., Pretlow, T. P. & Talbot, I. C., Apr 27 2002, In : Virchows Archiv. 440, 4, p. 362-366 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2001

Adhesion molecules and cancer

Charalabopoulos, K. & Pignatelli, M., Nov 28 2001, In : Archives of Hellenic Medicine. 18, 1, p. 16-19 4 p.

Research output: Contribution to journalEditorial

14 Citations (Scopus)

Expression patterns of β-catenin in in situ and invasive breast cancer

Karayiannakis, A. J., Nakopoulou, L., Gakiopoulou, H., Keramopoulos, A., Davaris, P. S. & Pignatelli, M., Jan 1 2001, In : European Journal of Surgical Oncology. 27, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines

Ei-Hariry, I., Pignatelli, M. & Lemoine, N. R., Jun 15 2001, In : British journal of cancer. 84, 12, p. 1656-1663 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

FGF-1 and FGF-2 regulate the expression of E-cadherin and catenins in pancreatic adenocarcinoma

El-Hariry, I., Pignatelli, M. & Lemoine, N. R., Dec 1 2001, In : International Journal of Cancer. 94, 5, p. 652-661 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

The potential role of abnormal E-cadherin and α-, β- and γ-catenin immunoreactivity in the determination of the biological behaviour of keratoacanthoma

Papadavid, E., Pignatelli, M., Zakynthinos, S., Krausz, T. & Chu, A. C., Dec 1 2001, In : British Journal of Dermatology. 145, 4, p. 582-589 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2000

Adhesion molecules as diagnostic tools in tumor pathology

Ohene-Abuakwa, Y. & Pignatelli, M., Jan 1 2000, In : International Journal of Surgical Pathology. 8, 3, p. 191-200 10 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)

Adhesion molecules in cancer biology

Ohene-Abuakwa, Y. & Pignatelli, M., Jan 1 2000, In : Advances in Experimental Medicine and Biology. 465, p. 115-126 12 p.

Research output: Contribution to journalReview article

35 Citations (Scopus)

Catenins and their associated proteins in colorectal cancer

Tucker, E. L. & Pignatelli, M., Jan 1 2000, In : Histology and Histopathology. 15, 1, p. 251-260 10 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Cell adhesion molecules in gynaecological cancer

Pignatelli, M., Weir, J., Sen, C. & Pawade, J., Dec 1 2000, In : CME Journal of Gynecologic Oncology. 5, 2, p. 194-201 8 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

E-cadherin-catenin cell-cell adhesion complex and human cancer

Wijnhoven, B. P. L., Dinjens, W. N. M. & Pignatelli, M., Aug 12 2000, In : British Journal of Surgery. 87, 8, p. 992-1005 14 p.

Research output: Contribution to journalArticle

373 Citations (Scopus)

Epithelial mucin expression in bladder cancer: Correlation with pathological and clinical parameters

Syrigos, K. N., Deonarain, D. M., Karayiannakis, A., Waxman, J., Krausz, T. & Pignatelli, M., Jan 1 2000, In : Urological Research. 28, 4, p. 241-245 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Expression of the E-cadherin/catenin (α-, β-, and γ-) complex correlates with the macroscopic appearance of early gastric cancer

Ohene-Abuakwa, Y., Noda, M., Perenyi, M., Kobayashi, N., Kashima, K., Hattori, T. & Pignatelli, M., Dec 19 2000, In : Journal of Pathology. 192, 4, p. 433-439 7 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Microsatellite instability and allelic imbalance in primary and secondary colorectal cancer

Schneider, A., Rohr, S., Kelly, M. D., Mitry, R., Pignatelli, M., Dore, C. J., Gaub, M. P., Jaeck, D., Meyer, C., Oudet, P. & Habib, N. A., Sep 4 2000, In : Australian and New Zealand Journal of Surgery. 70, 8, p. 587-592 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Mucins and mucosal protection in the gastrointestinal tract: New prospects for mucins in the pathology of gastrointestinal disease

Corfield, A. P., Myerscough, N., Longman, R., Sylvester, P., Arul, S. & Pignatelli, M., Oct 7 2000, In : Gut. 47, 4, p. 589-594 6 p.

Research output: Contribution to journalReview article

256 Citations (Scopus)

Source of oncofetal ED-B-containing fibronectin: Implications of production of both tumor and endothelial cells

Midulla, M., Verma, R., Pignatelli, M., Ritter, M. A., Courtenay-Luck, N. S. & George, A. J. T., Jan 1 2000, In : Cancer Research. 60, 1, p. 164-169 6 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Systemic effect of peanut agglutinin following intravenous infusion into rats

Jordinson, M., Fitzgerald, A. J., Goodlad, R. A., Brynes, A., Grant, G., Pignatelli, M. & Calam, J., Jun 26 2000, In : Alimentary Pharmacology and Therapeutics. 14, 6, p. 835-840 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1999

Abnormal expression and function of the E-cadherin-catenin complex in gastric carcinoma cell lines

Jawhari, A. U., Noda, M., Farthing, M. J. G. & Pignatelli, M., Jan 1 1999, In : British journal of cancer. 80, 3-4, p. 322-330 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abnormal expression of the E-cadherin-catenin complex in dysplastic Barrett's oesophagus

Seery, J. P., Syrigos, K. N., Karayiannakis, A. J., Valizadeh, A. & Pignatelli, M., Dec 10 1999, In : Acta Oncologica. 38, 7, p. 945-948 4 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)