• 9112 Citations
  • 53 h-Index
1982 …2014
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Research Output 1982 2014

  • 9112 Citations
  • 53 h-Index
  • 165 Article
  • 1 Chapter
2014
Catenins
Cadherins
Stomach
Carcinoma
Cell Line
2012
14 Citations (Scopus)

Characterization of a novel oral glucocorticoid system and its possible role in disease

Cirillo, N., Hassona, Y., Pignatelli, M., Gasparoto, T. H., Morgan, D. J. & Prime, S. S., Jan 2012, In : Journal of Dental Research. 91, 1, p. 97-103 7 p.

Research output: Contribution to journalArticle

Glucocorticoids
Hydrocortisone
Mouth Mucosa
Keratinocytes
Adrenal Cortex Hormones
54 Citations (Scopus)

Prevalence of different subtypes of serrated polyps and risk of synchronous advanced colorectal neoplasia in average-risk population undergoing first-time colonoscopy

Buda, A., De Bona, M., Dotti, I., Piselli, P., Zabeo, E., Barbazza, R., Bellumat, A., Valiante, F., Nardon, E., Probert, C. S., Pignatelli, M., Stanta, G., Sturniolo, G. & De Boni, M., 2012, In : Clinical and Translational Gastroenterology. 3

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Adenoma
Population
Neoplasms
20 Citations (Scopus)

Regulatory function of trefoil peptides (TFF) on intestinal cell junctional complexes

Buda, A., Jepson, M. A. & Pignatelli, M., Oct 2012, In : Cell Communication and Adhesion. 19, 5-6, p. 63-68 6 p.

Research output: Contribution to journalArticle

Peptides
Junctional Adhesion Molecules
Claudin-1
Occludin
Catenins
2011
46 Citations (Scopus)

E-cadherin and the cytoskeletal network in colorectal cancer development and metastasis

Buda, A. & Pignatelli, M., Dec 2011, In : Cell Communication and Adhesion. 18, 6, p. 133-143 11 p.

Research output: Contribution to journalArticle

Cadherins
Cell Movement
Actins
Colorectal Neoplasms
Neoplasm Metastasis
1 Citation (Scopus)
1,2-Dimethylhydrazine
beta Catenin
Cyclooxygenase 2
Tumors
Down-Regulation
8 Citations (Scopus)

The actin-bundling protein Fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair

Qualtrough, D., Smallwood, K., Littlejohns, D. & Pignatelli, M., Feb 23 2011, In : BMC Gastroenterology. 11, 14.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Actins
Proteins
Cell Movement
Butyric Acid
2010
9 Citations (Scopus)

Role of human tissue kallikrein in gastrointestinal stromal tumour invasion

Dominek, P., Campagnolo, P., H-Zadeh, M., Kränkel, N., Chilosi, M., Sharman, J. A., Caporali, A., Mangialardi, G., Spinetti, G., Emanueli, C., Pignatelli, M. & Madeddu, P., Oct 26 2010, In : British Journal of Cancer. 103, 9, p. 1422-1431 10 p.

Research output: Contribution to journalArticle

Tissue Kallikreins
Gastrointestinal Stromal Tumors
Stromal Cells
Kinins
Cell Movement
2009
23 Citations (Scopus)

The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro

Qualtrough, D., Singh, K., Banu, N., Paraskeva, C. & Pignatelli, M., 2009, In : British Journal of Cancer. 101, 7, p. 1124-1129 6 p.

Research output: Contribution to journalArticle

Adenoma
Actins
Proteins
Cell Movement
Colorectal Neoplasms

The Molecular Pathology of Sporadic and Hereditary Colorectal Cancer

Pignatelli, M., Banu, N. & Melegh, Z., Jan 14 2009, Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach. Blackwell Publishing Ltd., p. 305-316 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular Pathology
Colorectal Neoplasms
2007
37 Citations (Scopus)

Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: Possibilities for combination therapy

Banu, N., Buda, A., Chell, S., Elder, D., Moorghen, M., Paraskeva, C., Qualtrough, D. & Pignatelli, M., Oct 2007, In : Cell Proliferation. 40, 5, p. 768-779 12 p.

Research output: Contribution to journalArticle

Cyclooxygenase 2
Epidermal Growth Factor Receptor
Colonic Neoplasms
Transcriptional Activation
Cell Movement
2006
72 Citations (Scopus)

Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations

Carvajal-Carmona, L. G., Alam, N. A., Pollard, P. J., Jones, A. M., Barclay, E., Wortham, N., Pignatelli, M., Freeman, A., Pomplun, S., Ellis, I., Poulsom, R., El-Bahrawy, M. A., Berney, D. M. & Tomlinson, I. P. M., 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 8, p. 3071-3075 5 p.

Research output: Contribution to journalArticle

Fumarate Hydratase
Leydig Cell Tumor
Testis
Tumors
Mutation
53 Citations (Scopus)

Soluble IGF2 receptor rescues ApcMin/+ intestinal adenoma progression induced by Igf2 loss of imprinting

Harper, J., Burns, J. L., Foulstone, E. J., Pignatelli, M., Zaina, S. & Hassan, A. B., Feb 15 2006, In : Cancer Research. 66, 4, p. 1940-1948 9 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor II
Adenoma
Ligands
Colorectal Neoplasms
Alleles
2005
35 Citations (Scopus)

Activated Akt expression in breast cancer: Correlation with p53, Hdm2 and patient outcome

Vestey, S. B., Sen, C., Calder, C. J., Perks, C. M., Pignatelli, M. & Winters, Z. E., May 2005, In : European Journal of Cancer. 41, 7, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Protein Isoforms
Proto-Oncogene Proteins c-akt
Serine
Disease-Free Survival
22 Citations (Scopus)
Laryngopharyngeal Reflux
Molecular Models
Larynx
Tight Junctions
Swine
72 Citations (Scopus)

Laryngeal epithelial defenses against laryngopharyngeal reflux: Investigations of E-cadherin, carbonic anhydrase isoenzyme III, and pepsin

Gill, G. A., Johnston, N., Buda, A., Pignatelli, M., Pearson, J., Dettmar, P. W. & Koufman, J., Dec 2005, In : Annals of Otology, Rhinology and Laryngology. 114, 12 I, p. 913-921 9 p.

Research output: Contribution to journalArticle

Carbonic Anhydrase III
Laryngopharyngeal Reflux
Pepsin A
Cadherins
Isoenzymes
37 Citations (Scopus)

Reduced p120ctn expression correlates with poor survival in patients with adenocarcinoma of the gastroesophageal junction

Wijnhoven, B. P. L., Pignatelli, M., Dinjens, W. N. M. & Tilanus, H. W., Nov 1 2005, In : Journal of Surgical Oncology. 92, 2, p. 116-123 8 p.

Research output: Contribution to journalArticle

Esophagogastric Junction
Adenocarcinoma
Survival
Barrett Esophagus
Neoplasms
2004
69 Citations (Scopus)

A Multicenter Phase I Gene Therapy Clinical Trial Involving Intraperitoneal Administration of E1A-Lipid Complex in Patients with Recurrent Epithelial Ovarian Cancer Overexpressing HER-2/neu Oncogene

Madhusudan, S., Tamir, A., Bates, N., Flanagan, E., Gore, M. E., Barton, D. P. J., Harper, P., Seckl, M., Thomas, H., Lemoine, N. R., Charnock, M., Habib, N. A., Lechler, R., Nicholls, J., Pignatelli, M. & Ganesan, T. S., May 1 2004, In : Clinical Cancer Research. 10, 9, p. 2986-2996 11 p.

Research output: Contribution to journalArticle

Oncogenes
Genetic Therapy
Clinical Trials
Lipids
DNA
6 Citations (Scopus)

Biochemical analysis and subcellular distribution of E-cadherin-catenin in adenocarcinomas of the gastro-oesophageal junction

Wijnhoven, B. P. L., Tucker, E. T., Dinjens, W. N. M., Tilanus, H. W. & Pignatelli, M., May 2004, In : Anticancer Research. 24, 3 A, p. 1369-1375 7 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Adenocarcinoma
Membranes
Neoplasms
47 Citations (Scopus)

Cytoskeletal network in colon cancer: From genes to clinical application

Buda, A. & Pignatelli, M., May 2004, In : International Journal of Biochemistry and Cell Biology. 36, 5, p. 759-765 7 p.

Research output: Contribution to journalArticle

Neoplasm Genes
Colonic Neoplasms
Actins
Colorectal Neoplasms
Genes
16 Citations (Scopus)

p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2.

Vestey, S. B., Sen, C., Calder, C. J., Perks, C. M., Pignatelli, M. & Winters, Z. E., 2004, In : Breast cancer research : BCR. 6, 5

Research output: Contribution to journalArticle

Tumor Suppressor Protein p14ARF
Carcinoma, Intraductal, Noninfiltrating
Breast Neoplasms
Breast Carcinoma In Situ
Survival
2003
13 Citations (Scopus)

Abnormalities of the cadherin-catenin complex in chemically-induced colo-rectal carcinogenesis

Tucker, E., Buda, A., Janghra, N., Baker, J., Coad, J., Moorghan, M., Havler, M., Dettmar, P. & Pignatelli, M., Feb 2003, In : Proceedings of the Nutrition Society. 62, 1, p. 229-236 8 p.

Research output: Contribution to journalArticle

Catenins
cadherins
Cadherins
carcinogenesis
Carcinogenesis
29 Citations (Scopus)

Butyrate downregulates α2β1 integrin: A possible role in the induction of apoptosis in colorectal cancer cell lines

Buda, A., Qualtrough, D., Jepson, M. A., Martines, D., Paraskeva, C. & Pignatelli, M., May 1 2003, In : Gut. 52, 5, p. 729-734 6 p.

Research output: Contribution to journalArticle

Butyrates
Integrins
Colorectal Neoplasms
Down-Regulation
Apoptosis
135 Citations (Scopus)

Cell biology of laryngeal epithelial defenses in health and disease: Further studies

Bulmer, D., Ross, P. E., Axford, S. E., Johnston, N., Gill, G. A., Pearson, J. P., Dettmar, P. W., Panetti, M., Pignatelli, M. & Koufman, J. A., Jun 1 2003, In : Annals of Otology, Rhinology and Laryngology. 112, 6, p. 481-491 11 p.

Research output: Contribution to journalArticle

Laryngopharyngeal Reflux
Laryngeal Mucosa
Cell Biology
Epithelium
Health

Erratum: Abnormalities of the cadherin-catenin complex in chemically-induced colo-rectal carcinogenesis (Proceedings of the Nutrition Society (2003) 62:1 (230-231))

Tucker, E., Buda, A., Janghra, N., Baker, J., Coad, J., Moorghan, M., Halver, M., Dettmar, P. & Pignatelli, M., May 2003, In : Proceedings of the Nutrition Society. 62, 2, p. 571 1 p.

Research output: Contribution to journalArticle

cadherins
carcinogenesis
nutrition
170 Citations (Scopus)

Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro

Jawhari, A. U., Buda, A., Jenkins, M., Shehzad, K., Sarraf, C., Noda, M., Farthing, M. J. G., Pignatelli, M. & Adams, J. C., Jan 1 2003, In : American Journal of Pathology. 162, 1, p. 69-80 12 p.

Research output: Contribution to journalArticle

Actins
Cell Differentiation
Epithelial Cells
Cell Surface Extensions
Cell Movement
2002
40 Citations (Scopus)

Abnormal immunoreactivity of the E-cadherin/catenin (α-, β-, and γ-) complex in premalignant and malignant non-melanocytic skin tumours

Papadavid, E., Pignatelli, M., Zakynthinos, S., Krausz, T. & Chu, A. C., 2002, In : Journal of Pathology. 196, 2, p. 154-162 9 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Skin
Kidney
Neoplasms
58 Citations (Scopus)

Abnormal α-catenin expression in invasive breast cancer correlates with poor patient survival

Nakopoulou, L., Gakiopoulou-Givalou, H., Karayiannakis, A. J., Giannopoulou, I., Keramopoulos, A., Davaris, P. & Pignatelli, M., 2002, In : Histopathology. 40, 6, p. 536-546 11 p.

Research output: Contribution to journalArticle

Catenins
Breast Neoplasms
Cadherins
Survival
Survival Analysis
3 Citations (Scopus)

Genetics - Cellular basis

Buda, A. & Pignatelli, M., 2002, In : British Medical Bulletin. 64, p. 45-58 14 p.

Research output: Contribution to journalArticle

Intestinal Mucosa
Epigenomics
Carcinogenesis
Epithelial Cells
Growth
19 Citations (Scopus)

Molecular histology in the study of solid tumours

Campbell, R. J. & Pignatelli, M., 2002, In : Journal of Clinical Pathology. 55, 2, p. 80-82 3 p.

Research output: Contribution to journalArticle

Histology
Catenins
Immunohistochemistry
Cadherins
Neoplasms
308 Citations (Scopus)

β-catenin - A linchpin in colorectal carcinogenesis?

Wong, N. A. C. S. & Pignatelli, M., 2002, In : American Journal of Pathology. 160, 2, p. 389-401 13 p.

Research output: Contribution to journalArticle

Catenins
Carcinogenesis
TCF Transcription Factors
Colorectal Neoplasms
Transcription Factor 7-Like 2 Protein
20 Citations (Scopus)

β-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis

Hao, X., Frayling, I. M., Willcocks, T. C., Han, W., Tomlinson, I. P., Pignatelli, M. N., Pretlow, T. P. & Talbot, I. C., 2002, In : Virchows Archiv. 440, 4, p. 362-366 5 p.

Research output: Contribution to journalArticle

Catenins
Adenomatous Polyposis Coli
Loss of Heterozygosity
Carcinogenesis
Adenoma
2001
14 Citations (Scopus)

Adhesion molecules and cancer

Charalabopoulos, K. & Pignatelli, M., 2001, In : Archives of Hellenic Medicine. 18, 1, p. 16-19 4 p.

Research output: Contribution to journalArticle

Neoplasms
55 Citations (Scopus)

Expression patterns of β-catenin in in situ and invasive breast cancer

Karayiannakis, A. J., Nakopoulou, L., Gakiopoulou, H., Keramopoulos, A., Davaris, P. S. & Pignatelli, M., 2001, In : European Journal of Surgical Oncology. 27, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

Catenins
Breast Neoplasms
Lobular Carcinoma
Ductal Carcinoma
Carcinoma, Intraductal, Noninfiltrating
21 Citations (Scopus)

FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines

Ei-Hariry, I., Pignatelli, M. & Lemoine, N. R., Jun 15 2001, In : British Journal of Cancer. 84, 12, p. 1656-1663 8 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Catenins
Fibroblast Growth Factor 2
Cadherins
Fibroblast Growth Factor Receptors
28 Citations (Scopus)

FGF-1 and FGF-2 regulate the expression of E-cadherin and catenins in pancreatic adenocarcinoma

El-Hariry, I., Pignatelli, M. & Lemoine, N. R., Dec 1 2001, In : International Journal of Cancer. 94, 5, p. 652-661 10 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 1
Catenins
Fibroblast Growth Factor 2
Cadherins
Adenocarcinoma
22 Citations (Scopus)

The potential role of abnormal E-cadherin and α-, β- and γ-catenin immunoreactivity in the determination of the biological behaviour of keratoacanthoma

Papadavid, E., Pignatelli, M., Zakynthinos, S., Krausz, T. & Chu, A. C., 2001, In : British Journal of Dermatology. 145, 4, p. 582-589 8 p.

Research output: Contribution to journalArticle

Keratoacanthoma
Catenins
Cadherins
Squamous Cell Carcinoma
Warts
2000
33 Citations (Scopus)

Adhesion molecules as diagnostic tools in tumor pathology

Ohene-Abuakwa, Y. & Pignatelli, M., 2000, In : International Journal of Surgical Pathology. 8, 3, p. 191-200 10 p.

Research output: Contribution to journalArticle

Pathology
Biological Phenomena
Neoplasms
Cadherins
Tumor Biomarkers
35 Citations (Scopus)

Adhesion molecules in cancer biology

Ohene-Abuakwa, Y. & Pignatelli, M., 2000, In : Advances in Experimental Medicine and Biology. 465, p. 115-126 12 p.

Research output: Contribution to journalArticle

CD44 Antigens
Selectins
Cell Adhesion Molecules
Cadherins
Integrins
23 Citations (Scopus)

Catenins and their associated proteins in colorectal cancer

Tucker, E. L. & Pignatelli, M., Jan 2000, In : Histology and Histopathology. 15, 1, p. 251-260 10 p.

Research output: Contribution to journalArticle

Catenins
Colorectal Neoplasms
Adenomatous Polyposis Coli
Adenoma
APC Genes
1 Citation (Scopus)

Cell adhesion molecules in gynaecological cancer

Pignatelli, M., Weir, J., Sen, C. & Pawade, J., 2000, In : CME Journal of Gynecologic Oncology. 5, 2, p. 194-201 8 p.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Neoplasms
365 Citations (Scopus)

E-cadherin-catenin cell-cell adhesion complex and human cancer

Wijnhoven, B. P. L., Dinjens, W. N. M. & Pignatelli, M., 2000, In : British Journal of Surgery. 87, 8, p. 992-1005 14 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Cell Adhesion
Neoplasms
Proteins
2 Citations (Scopus)

Epithelial mucin expression in bladder cancer: Correlation with pathological and clinical parameters

Syrigos, K. N., Deonarain, D. M., Karayiannakis, A., Waxman, J., Krausz, T. & Pignatelli, M., 2000, In : Urological Research. 28, 4, p. 241-245 5 p.

Research output: Contribution to journalArticle

Mucin-1
Mucins
Urinary Bladder Neoplasms
Urinary Bladder
pemtumomab
44 Citations (Scopus)

Expression of the E-cadherin/catenin (α-, β-, and γ-) complex correlates with the macroscopic appearance of early gastric cancer

Ohene-Abuakwa, Y., Noda, M., Perenyi, M., Kobayashi, N., Kashima, K., Hattori, T. & Pignatelli, M., 2000, In : Journal of Pathology. 192, 4, p. 433-439 7 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Stomach Neoplasms
Neoplasms
Staining and Labeling
11 Citations (Scopus)

Microsatellite instability and allelic imbalance in primary and secondary colorectal cancer

Schneider, A., Rohr, S., Kelly, M. D., Mitry, R., Pignatelli, M., Dore, C. J., Gaub, M. P., Jaeck, D., Meyer, C., Oudet, P. & Habib, N. A., 2000, In : Australian and New Zealand Journal of Surgery. 70, 8, p. 587-592 6 p.

Research output: Contribution to journalArticle

Allelic Imbalance
Microsatellite Instability
Colorectal Neoplasms
Microsatellite Repeats
Neoplasms
252 Citations (Scopus)

Mucins and mucosal protection in the gastrointestinal tract: New prospects for mucins in the pathology of gastrointestinal disease

Corfield, A. P., Myerscough, N., Longman, R., Sylvester, P., Arul, S. & Pignatelli, M., 2000, In : Gut. 47, 4, p. 589-594 6 p.

Research output: Contribution to journalArticle

Gastrointestinal Diseases
Mucins
Gastrointestinal Tract
Pathology
Genes
53 Citations (Scopus)

Source of oncofetal ED-B-containing fibronectin: Implications of production of both tumor and endothelial cells

Midulla, M., Verma, R., Pignatelli, M., Ritter, M. A., Courtenay-Luck, N. S. & George, A. J. T., Jan 1 2000, In : Cancer Research. 60, 1, p. 164-169 6 p.

Research output: Contribution to journalArticle

Fibronectins
Endothelial Cells
Neoplasms
Staining and Labeling
Transformed Cell Line
7 Citations (Scopus)

Systemic effect of peanut agglutinin following intravenous infusion into rats

Jordinson, M., Fitzgerald, A. J., Goodlad, R. A., Brynes, A., Grant, G., Pignatelli, M. & Calam, J., 2000, In : Alimentary Pharmacology and Therapeutics. 14, 6, p. 835-840 6 p.

Research output: Contribution to journalArticle

Peanut Agglutinin
Intravenous Infusions
Large Intestine
Hormones
Lectins
1999
44 Citations (Scopus)

Abnormal expression and function of the E-cadherin-catenin complex in gastric carcinoma cell lines

Jawhari, A. U., Noda, M., Farthing, M. J. G. & Pignatelli, M., 1999, In : British Journal of Cancer. 80, 3-4, p. 322-330 9 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Stomach
Carcinoma
Cell Line
33 Citations (Scopus)

Abnormal expression of the E-cadherin-catenin complex in dysplastic Barrett's oesophagus

Seery, J. P., Syrigos, K. N., Karayiannakis, A. J., Valizadeh, A. & Pignatelli, M., 1999, In : Acta Oncologica. 38, 7, p. 945-948 4 p.

Research output: Contribution to journalArticle

Catenins
Barrett Esophagus
Cadherins
Staining and Labeling
Esophageal Neoplasms