Projects per year
Personal profile
Research Interests
We are interested in deciphering the molecular mechanisms that drive carcinogenesis and metastasis. We are particularly focused on the role of p53, which is deemed as the major tumour suppressor in humans.
Teaching
Currently, I am teaching Bioethics; Fuel Metabolism; Immunology
Publications
https://pubmed.ncbi.nlm.nih.gov/?term=Barlev+N&sort=pubdate
Professional Information
Editor of Springer-Nature journals: Cell Death Disease (IF=9), Cell Death Discovery (IF=6).
Education/Academic qualification
molecular biology, PhD, The role of HSF in heat shock response, Aarhus University
Award Date: Mar 14 1994
External positions
Professor
Sept 1 2022 → …
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Collaborations and top research areas from the last five years
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Projects
- 4 Active
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Patient derived lung cancer explants as a platform for validation of the correlation between CD320 and mutant p53
Lezina, L., Barlev, N. & Gushchin, D.
1/1/24 → 12/31/26
Project: FDCRGP
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Molecular mechanisms of solid cancer resistance to INFg/TNFa cytokines secreted by CAR-T cells
Barlev, N., Begimbetova, D. & Makishev, A.
1/1/24 → 12/31/26
Project: CRP
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Regulation of retromer-dependent protein sorting in health and disease
Kunz Halder, J., Batyrova, B., Khamijan, M., Barlev, N., Tanko, M. N., Bedford, M. T. & Owen, D. J.
1/1/24 → 12/31/26
Project: FDCRGP
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Dissecting Zeb1-mediated regulation of p53 during epithelial-mesenchymal transition (EMT) in cancer
1/1/23 → 12/31/25
Project: FDCRGP
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BRCA Mutations—The Achilles Heel of Breast, Ovarian and Other Epithelial Cancers
Loboda, A. P., Adonin, L. S., Zvereva, S. D., Guschin, D. Y., Korneenko, T. V., Telegina, A. V., Kondratieva, O. K., Frolova, S. E., Pestov, N. B. & Barlev, N. A., Mar 2023, In: International journal of molecular sciences. 24, 5, 4982.Research output: Contribution to journal › Review article › peer-review
Open Access11 Citations (Scopus) -
Zeb1-mediated autophagy enhances resistance of breast cancer cells to genotoxic drugs
Fedorova, O., Daks, A., Parfenyev, S., Shuvalov, O., Netsvetay, S., Vasileva, J., Gudovich, A., Golotin, V., Semenov, O., Petukhov, A., Baiduik, E., Berdigaliyev, N., Tulchinsky, E. M. & Barlev, N. A., Jan 22 2022, In: Biochemical and Biophysical Research Communications. 589, p. 29-34 6 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
EMT: A mechanism for escape from EGFR-targeted therapy in lung cancer
Tulchinsky, E., Demidov, O., Kriajevska, M., Barlev, N. A. & Imyanitov, E., Jan 2019, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1871, 1, p. 29-39 11 p.Research output: Contribution to journal › Review article › peer-review
154 Citations (Scopus) -
Erratum: Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB (Oncotarget (2012) 4 (362-372) DOI: 10.18632/oncotarget.901)
Aksenova, V., Turoverova, L., Khotin, M., Magnusson, K. E., Tulchinsky, E., Melino, G., Pinaev, G. P., Barlev, N. & Tentler, D., Sept 1 2018, In: Oncotarget. 9, 76, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB
Aksenova, V., Turoverova, L., Khotin, M., Magnusson, K. E., Tulchinsky, E., Melino, G., Pinaev, G. P., Barlev, N. & Tentler, D., 2013, In: Oncotarget. 4, 2, p. 362-372 11 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus)