Projects per year
Personal profile
Research Interests
We are interested in deciphering the molecular mechanisms that drive carcinogenesis and metastasis. We are particularly focused on the role of p53, which is deemed as the major tumour suppressor in humans.
Teaching
Currently, I am teaching Bioethics; Fuel Metabolism; Immunology
Publications
https://pubmed.ncbi.nlm.nih.gov/?term=Barlev+N&sort=pubdate
Professional Information
Editor of Springer-Nature journals: Cell Death Disease (IF=9), Cell Death Discovery (IF=6).
Education/Academic qualification
molecular biology, PhD, The role of HSF in heat shock response, Aarhus University
Award Date: Mar 14 1994
External positions
Professor
Sept 1 2022 → …
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Collaborations and top research areas from the last five years
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Regulation of retromer-dependent protein sorting
Kunz Halder, J. (PI), Batyrova, B. (PI), Barlev, N. (Other Faculty/Researcher), Bedford, M. T. (Other Faculty/Researcher) & Wymann, M. (Other Faculty/Researcher)
4/1/26 → 12/31/28
Project: FDCRGP
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Molecular mechanisms of solid cancer resistance to INFg/TNFa cytokines secreted by CAR-T cells
Barlev, N. (PI), Begimbetova, D. (Co-PI) & Makishev, A. (Co-PI)
1/1/24 → 12/31/26
Project: CRP
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Patient derived lung cancer explants as a platform for validation of the correlation between CD320 and mutant p53
Lezina, L. (PI), Barlev, N. (Other Faculty/Researcher) & Gushchin, D. (Other Faculty/Researcher)
1/1/24 → 12/31/26
Project: FDCRGP
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Dissecting Zeb1-mediated regulation of p53 during epithelial-mesenchymal transition (EMT) in cancer
Barlev, N. (PI) & Tulchinsky, E. (Co-PI)
1/1/23 → 3/31/26
Project: FDCRGP
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Decoding the Snail transcriptional network: its role in cancer progression and therapy
Parfenyev, S. E., Nazarov, A. N., Daks, A. A., Fedorova, O. A., Barlev, N. A. & Shuvalov, O. Y., Dec 2026, In: Biology Direct. 21, 1, 69.Research output: Contribution to journal › Review article › peer-review
Open Access -
Methyltransferase SETD7 as a Regulator of STING-Dependent Cytokine Response in Lung Cancer Cells
Nevzorov, I. A., Korableva, P., Shuvalov, O., Parfenyev, S., Barlev, N. A. & Daks, A., May 2026, In: International journal of molecular sciences. 27, 9, 4020.Research output: Contribution to journal › Article › peer-review
Open Access -
Comprehensive analysis of cellular metrics: From proliferation to mitochondrial membrane potential and cell death in a single sample
Sabirova, S., Sharapova, G., Budyukova, A., Gomzikova, M., Brichkina, A., Barlev, N. A., Rizvanov, A., Markov, N. & Simon, H. U., Dec 2025, In: Cell Death Discovery. 11, 1, 119.Research output: Contribution to journal › Article › peer-review
Open Access23 Link opens in a new tab Citations (Scopus) -
Dietary Polyphenol Combinations Have a Multifaceted Inhibitory Effect on Metabolic Rewiring and Signaling Pathways in Neuroblastoma
Karpova, N., Fefilova, E., Daks, A., Parfenyev, S., Nazarov, A., Barlev, N. A. & Shuvalov, O., Nov 2025, In: Pharmaceuticals. 18, 11, 1717.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Dualistic role of ZEB1 and ZEB2 in tumor progression
Parfenyev, S. E., Daks, A. A., Shuvalov, O. Y., Fedorova, O. A., Pestov, N. B., Korneenko, T. V. & Barlev, N. A., Dec 2025, In: Biology Direct. 20, 1, 32.Research output: Contribution to journal › Review article › peer-review
Open Access18 Link opens in a new tab Citations (Scopus)