Infectious triggers of chronic autoimmunity in spondyloarthropathy (CITAS)

  • Kunz Halder, Jeanette (PI)
  • Kushugulova, Almagul (Co-PI)
  • Ainabekova, Bayan (Co-PI)
  • Adilbayeva, Altynay (Postdoctoral scholar (PhD degree holder))
  • Zhubanchaliyev, Altynbek (Other Faculty/Researcher)
  • Sharip, Aigul (Other Faculty/Researcher)
  • Nurgaziyeva, Ayaulym (Other Faculty/Researcher)
  • Meiramova, Assel (Other Faculty/Researcher)
  • Isilbayeva, Argul (Other Faculty/Researcher)
  • Beeton, Christine (Other Faculty/Researcher)
  • Forslund, Sofia (Other Faculty/Researcher)
  • Poddighe, Dimitri (Other Faculty/Researcher)

Project: CRP

Project Details

Grant Program

Collaborative Research Program 2021-2023

Project Description

The overall goal of the cluster "Infectious triggers of chronic autoimmunity in Spondyloarthropathy " (CITAS) is to provide a better understanding of disease pathology of Spondyloarthritis (SpA) - with a focus on open issues relevant to Kazakhstan - to promote the development of new therapeutic and diagnostic avenues for SpA patients. Although a relatively rare disease, SpA is the prototype of an autoimmune disease due to the well-understood genetic contribution by the human leukocyte antigen (HLA) B27 locus. In addition, one of the triggers linked to SpA pathogenesis – the zoonotic infectious disease Brucellosis - is endemic in Kazakhstan.
StatusActive
Effective start/end date1/1/21 → 12/31/25

Keywords

  • Spondyloarthritis
  • immunity
  • inflammation
  • Brucellosis
  • microbiome

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  • 2 Publication peer-review