Next-generation, whole genome sequencing-based analysis of Hepatitis C virus circulating variants, transmission dynamics, and drug resistance-associated substitutions in Kazakhstan

Project: CRP

Project Details

Grant Program

Collaborative Research Program for 2025-2027

Project Description

The research proposal aims to conduct a next-generation, whole sequencing-based analysis of Hepatitis C virus (HCV) circulating variants, transmission dynamics, and drug resistance-associated substitutions in Kazakhstan. The study will address the limited epidemiological and modeling studies related to HCV prevalence in Kazakhstan and aims to provide valuable insights into HCV genotypes, recombinant forms, transmission patterns, and drug resistance. The outcomes of this research are expected to contribute to the optimization of HCV management and treatment strategies, particularly in the context of genotype-specific responses and the emergence of drug resistance-associated substitutions.
Short titleHCV molecular epidemiology in Kazakhstan
StatusActive
Effective start/end date1/1/2512/31/27

Keywords

  • HCV
  • Next-generation sequencing
  • Molecular Epidemiology
  • Phylogenetics
  • Drug resistance

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