Research output per year
Research output per year
Project Details
Grant Program
Faculty-development competitive research grants program for 2021-2022 (Covid-19 project)
Project Description
Glycogen synthase kinase 3 (GSK3) plays a critical role in viral assembly and replication of SARS-CoV suggesting that inhibition of GSK3 kinase activity by lithium chloride (LiCl) will inhibit a propagation of SARS-CoV-2. To determine the efficacy of LiCl, we propose to carry out a randomized clinical trial studies (Phase I- safety) and (Phase II-efficacy) to determine how effective an inhalation of LiCl in treatment of COVID-19 patients.
| Short title | Lithium Chloride aerosol to treat COVID-19 |
|---|---|
| Status | Finished |
| Effective start/end date | 1/1/21 → 12/31/23 |
Keywords
- COVID-19, SARS-CoV-2
- Lithium Chloride
- Virus replication and assembly
- clinical trial studies Phase I and Phase II
- aerosol, inhalation
- glycogen synthase 3
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Research output
- 2 Article
-
Universal whole-genome Oxford nanopore sequencing of SARS-CoV-2 using tiled amplicons
Kalendar, R., Kairov, U., Karabayev, D., Aitkulova, A. M., Tynyshtykbayeva, N., Daniyarov, A., Otarbay, Z., Rakhimova, S., Akilzhanova, A. & Sarbassov, D., Jun 26 2023, In: Scientific Reports. 13, 10334.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)62 Downloads (Pure) -
A high scale SARS-CoV-2 profiling by its whole-genome sequencing using Oxford Nanopore Technology in Kazakhstan
Kairov, U., Amanzhanova, A., Karabayev, D., Rakhimova, S., Aitkulova, A., Samatkyzy, D., Kalendar, R., Kozhamkulov, U., Molkenov, A., Gabdulkayum, A., Sarbassov, D. & Akilzhanova, A., 2022, In: Frontiers in Genetics. 13, p. 906318Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)