Glycogen synthase kinase 3 (GSK3) plays a critical role in viral assembly and replication of SARS-CoV suggesting that inhibition of GSK3 kinase activity by lithium chloride (LiCl) will inhibit a propagation of SARS-CoV-2. To determine the efficacy of LiCl, we propose to carry out a randomized clinical trial studies (Phase I- safety) and (Phase II-efficacy) to determine how effective an inhalation of LiCl in treatment of COVID-19 patients.
|Short title||Lithium Chloride aerosol to treat COVID-19|
- COVID-19, SARS-CoV-2
- Lithium Chloride
- Virus replication and assembly
- clinical trial studies Phase I and Phase II
- aerosol, inhalation
- glycogen synthase 3