Understanding the genetic architecture of Alzheimer's disease in Kazakhstan

  • Kunz Halder, Jeanette (PI)
  • Askarova, Sholpan (Co-PI)
  • Alzhanova, Dinara (Co-PI)
  • Khuanbai, Yerkanat (Other Faculty/Researcher)
  • Mukhatayev, Zhussipbek (Other Faculty/Researcher)
  • Batyrova, Banu (Other Faculty/Researcher)
  • Kaiyrlykyzy, Aiym (Other Faculty/Researcher)
  • Djansugurova, Leyla (Other Faculty/Researcher)

Project: CRP

Project Details

Grant Program

Collaborative Research Program 2024-2026

Project Description

The overall goal of our collaborative cluster is to advance our understanding of the complex etiology of Alzheimer's disease (AD) in Kazakhstan with a particular focus on the roles of the gut-brain axis, systemic inflammation, and genetic risk factors in AD development. AD is a global health issue, often unrecognized or misdiagnosed in underserved regions such as Kazakhstan where AD is not commonly acknowledged as a disease.
StatusActive
Effective start/end date1/1/2412/31/26

Keywords

  • Alzheimer's disease
  • Dementia
  • ApoE
  • Inflammation
  • Genotyping
  • Gut-brain-axis

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