TY - JOUR
T1 - 3D structured capillary cell suspensions aided by aqueous two-phase systems
AU - Dyab, Amro
PY - 2024/10/8
Y1 - 2024/10/8
N2 - We report a facile technique for 3D structuring of living cells by forming capillary cell suspensions based on an aqueous two-phase system (ATPS) of polyethylene glycol (PEG) and dextran (DEX) solutions. We demonstrate the formation of water-in-water (DEX-in-PEG) capillary bridges using concentrated suspensions of yeast cells which show enhanced rheological properties and distinctive 3D patterns. Capillary structured cell suspensions can potentially find applications in novel ways of 3D cell culturing, instant tissue engineering and many biomedical investigations.
AB - We report a facile technique for 3D structuring of living cells by forming capillary cell suspensions based on an aqueous two-phase system (ATPS) of polyethylene glycol (PEG) and dextran (DEX) solutions. We demonstrate the formation of water-in-water (DEX-in-PEG) capillary bridges using concentrated suspensions of yeast cells which show enhanced rheological properties and distinctive 3D patterns. Capillary structured cell suspensions can potentially find applications in novel ways of 3D cell culturing, instant tissue engineering and many biomedical investigations.
UR - https://pubs.rsc.org/en/Content/ArticleLanding/2024/TB/D4TB01296H
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85206016053&origin=SingleRecordEmailAlert&dgcid=raven_sc_affil_en_us_email&txGid=636caa767b11c0d98837f1efe417c5e0
U2 - 10.1039/D4TB01296H
DO - 10.1039/D4TB01296H
M3 - Article
SN - 2050-7518
SP - 10215
JO - Journal of Materials Chemistry B
JF - Journal of Materials Chemistry B
ER -