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Author

  • Eugene Tulchinsky
2015

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity

Gilan, O., Diesch, J., Amalia, M., Jastrzebski, K., Chueh, A. C., Verrills, N. M., Pearson, R. B., Mariadason, J. M., Tulchinsky, E., Hannan, R. D. & Dhillon, A. S., Mar 5 2015, In : Oncogene. 34, 10, p. 1333-1339 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2014

Widespread FRA1-Dependent Control of Mesenchymal Transdifferentiation Programs in Colorectal Cancer Cells

Diesch, J., Sanij, E., Gilan, O., Love, C., Tran, H., Fleming, N. I., Ellul, J., Amalia, M., Haviv, I., Pearson, R. B., Tulchinsky, E., Mariadason, J. M., Sieber, O. M., Hannan, R. D. & Dhillon, A. S., Mar 21 2014, In : PLoS One. 9, 3, e88950.

Research output: Contribution to journalArticle

Open Access
45 Citations (Scopus)
2018

Assessment of Nuclear ZEB2 as a Biomarker for Colorectal Cancer Outcome and TNM Risk Stratification

Sreekumar, R., Harris, S., Moutasim, K., DeMateos, R., Patel, A., Emo, K., White, S., Yagci, T., Tulchinsky, E., Thomas, G., Primrose, J. N., Sayan, A. E. & Mirnezami, A. H., Oct 5 2018, In : JAMA network open. 1, 6, p. e183115

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2017

Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells

Wan Makhtar, W. R., Browne, G., Karountzos, A., Stevens, C., Alghamdi, Y., Bottrill, A. R., Mistry, S., Smith, E., Bushel, M., Pringle, J. H., Sayan, A. E. & Tulchinsky, E., Nov 23 2017, In : Oncogene. 36, 47, p. 6640-6648 9 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Colorectal cancer cells use the negative feedback regulators of WNT signalling to activate epithelial-mesenchymal transition pathways

Tulchinsky, E., Apr 1 2017, In : Gut. 66, 4, p. 563-564 2 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)
2013

A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma

Caramel, J., Papadogeorgakis, E., Hill, L., Browne, G. J., Richard, G., Wierinckx, A., Saldanha, G., sborne, J., Hutchinson, P., Tse, G., Lachuer, J., Puisieux, A., Pringle, J. H., Ansieau, S. & Tulchinsky, E., Oct 14 2013, In : Cancer Cell. 24, 4, p. 466-480 15 p.

Research output: Contribution to journalArticle

Open Access
235 Citations (Scopus)
2012

A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells

Pakay, J. L., Diesch, J., Gilan, O., Yip, Y. Y., Sayan, E., Kolch, W., Mariadason, J. M., Hannan, R. D., Tulchinsky, E. & Dhillon, A. S., Apr 5 2012, In : Oncogene. 31, 14, p. 1817-1824 8 p.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)
2014

Plasticity of melanoma and EMT-TF reprogramming

Tulchinsky, E., Howard Pringle, J., Caramel, J. & Ansieau, S., Jan 2014, In : Oncotarget. 5, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Open Access
17 Citations (Scopus)
2013

Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB

Aksenova, V., Turoverova, L., Khotin, M., Magnusson, K. E., Tulchinsky, E., Melino, G., Pinaev, G. P., Barlev, N. & Tentler, D., 2013, In : Oncotarget. 4, 2, p. 362-372 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2012

Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21

Masgras, I., Carrera, S., De Verdier, P. J., Brennan, P., Majid, A., Makhtar, W., Tulchinsky, E., Jones, G. D. D., Roninson, I. B. & Macip, S., Mar 23 2012, In : Journal of Biological Chemistry. 287, 13, p. 9845-9854 10 p.

Research output: Contribution to journalArticle

Open Access
57 Citations (Scopus)
2018

Erratum: Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB (Oncotarget (2012) 4 (362-372) DOI: 10.18632/oncotarget.901)

Aksenova, V., Turoverova, L., Khotin, M., Magnusson, K. E., Tulchinsky, E., Melino, G., Pinaev, G. P., Barlev, N. & Tentler, D., Sep 1 2018, In : Oncotarget. 9, 76, 1 p.

Research output: Contribution to journalComment/debate

2012

Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL

Sayan, A. E., Stanford, R., Vickery, R., Grigorenko, E., Diesch, J., Kulbicki, K., Edwards, R., Pal, R., Greaves, P., Jariel-Encontre, I., Piechaczyk, M., Kriajevska, M., Mellon, J. K., Dhillon, A. S. & Tulchinsky, E., Mar 22 2012, In : Oncogene. 31, 12, p. 1493-1503 11 p.

Research output: Contribution to journalArticle

Open Access
51 Citations (Scopus)
2019

Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC

Sreekumar, R., Emaduddin, M., Al-Saihati, H., Moutasim, K., Chan, J., Spampinato, M., Bhome, R., Yuen, H. M., Mescoli, C., Vitale, A., Cillo, U., Rugge, M., Primrose, J., Hilal, M. A., Thirdborough, S., Tulchinsky, E., Thomas, G., Mirnezami, A. & Sayan, A. E., Oct 1 2019, In : Cell Death and Disease. 10, 10, 703.

Research output: Contribution to journalArticle

Open Access

EMT: A mechanism for escape from EGFR-targeted therapy in lung cancer

Tulchinsky, E., Demidov, O., Kriajevska, M., Barlev, N. A. & Imyanitov, E., Jan 2019, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1871, 1, p. 29-39 11 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)
2015

The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma

Ramsdale, R., Jorissen, R. N., Li, F. Z., Al-Obaidi, S., Ward, T., Sheppard, K. E., Bukczynska, P. E., Young, R. J., Boyle, S. E., Shackleton, M., Bollag, G., Long, G. V., Tulchinsky, E., Rizos, H., Pearson, R. B., McArthur, G. A., Dhillon, A. S. & Ferrao, P. T., Aug 18 2015, In : Science Signaling. 8, 390, p. ra82

Research output: Contribution to journalArticle

55 Citations (Scopus)
2019

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

Li, N., Babaei-Jadidi, R., Lorenzi, F., Spencer-Dene, B., Clarke, P., Domingo, E., Tulchinsky, E., Vries, R. G. J., Kerr, D., Pan, Y., He, Y., Bates, D. O., Tomlinson, I., Clevers, H. & Nateri, A. S., Mar 1 2019, In : Oncogenesis. 8, 3, 13.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins

Al-Ismaeel, Q., Neal, C. P., Al-Mahmoodi, H., Almutairi, Z., Al-Shamarti, I., Straatman, K., Jaunbocus, N., Irvine, A., Issa, E., Moreman, C., Dennison, A. R., Emre Sayan, A., McDearmid, J., Greaves, P., Tulchinsky, E. & Kriajevska, M., Jul 2 2019, In : British Journal of Cancer. 121, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

FRA-1 as a driver of tumour heterogeneity: A nexus between oncogenes and embryonic signalling pathways in cancer

Dhillon, A. S. & Tulchinsky, E., Aug 20 2015, In : Oncogene. 34, 34, p. 4421-4428 8 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)
2012

ZEB/miR-200 feedback loop: At the crossroads of signal transduction in cancer

Hill, L., Browne, G. & Tulchinsky, E., Feb 15 2012, In : International Journal of Cancer. 132, 4, p. 745-754 10 p.

Research output: Contribution to journalReview article

144 Citations (Scopus)