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  • Zhaxybay Zhumadilov
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2019

Independent Component Analysis for Unraveling the Complexity of Cancer Omics Datasets

Sompairac, N., Nazarov, P. V., Czerwinska, U., Cantini, L., Biton, A., Molkenov, A., Zhumadilov, Z., Barillot, E., Radvanyi, F., Gorban, A., Kairov, U. & Zinovyev, A., Sep 7 2019, In : International Journal of Molecular Sciences. 20, 18, 4414.

Research output: Contribution to journal › Review article

Open Access
3 Citations (Scopus)

Short-Chain Fatty Acid Propionate Protects from Hypertensive Cardiovascular Damage

Bartolomaeus, H., Balogh, A., Yakoub, M., Homann, S., Markó, L., Höges, S., Tsvetkov, D., Krannich, A., Wundersitz, S., Avery, E. G., Haase, N., Kräker, K., Hering, L., Maase, M., Kusche-Vihrog, K., Grandoch, M., Fielitz, J., Kempa, S., Gollasch, M., Zhumadilov, Z. & 9 others, Kozhakhmetov, S., Kushugulova, A., Eckardt, K. U., Dechend, R., Rump, L. C., Forslund, S. K., Müller, D. N., Stegbauer, J. & Wilck, N., Mar 12 2019, In : Circulation. 139, 11, p. 1407-1421 15 p.

Research output: Contribution to journal › Article

Open Access
40 Citations (Scopus)
2018

Genetic Epidemiologyof Ventricular Tachycardia in Patients with Cardiomyopathy in Kazakhstan: ATargeted Sequencing Study

Bekbossynova, M., Akilzhanova, A., Guelly, C., Abilova, Z., Akhmetova, A., Kairov, U., Nuralinov, O., Rashbayeva, G., Trajanoski, S., Abdirova, B. & Zhumadilov, Z., Apr 1 2018, In : Journal of Heart and Lung Transplantation. 37, 4, p. S322

Research output: Contribution to journal › Article

Metagenomic analysis of gut microbial communities from a Central Asian population

Kushugulova, A., Forslund, S. K., Costea, P. I., Kozhakhmetov, S., Khassenbekova, Z., Urazova, M., Nurgozhin, T., Zhumadilov, Z., Benberin, V., Driessen, M., Hercog, R., Voigt, A. Y., Benes, V., Kandels-Lewis, S., Sunagawa, S., Letunic, I. & Bork, P., Jul 1 2018, In : BMJ Open. 8, 7, e021682.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Transcriptomic databases

Molkenov, A., Zhelambayeva, A., Yermekov, A., Mussurova, S., Sarkytbayeva, A., Kalykhbergenov, Y., Zhumadilov, Z. & Kairov, U., Jan 1 2018, Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics. Elsevier B.V., Vol. 1-3. p. 341-351 11 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2017

A review of the biomedical innovations for healthy longevity

Moskalev, A., Anisimov, V., Aliper, A., Artemov, A., Asadullah, K., Belsky, D., Baranova, A., de Grey, A., Dixit, V. D., Debonneuil, E., Dobrovolskaya, E., Fedichev, P., Fedintsev, A., Fraifeld, V., Franceschi, C., Freer, R., Fülöp, T., Feige, J., Gems, D., Gladyshev, V. & 30 others, Gorbunova, V., Irincheeva, I., Jager, S., Jazwinski, S. M., Kaeberlein, M., Kennedy, B., Khaltourina, D., Kovalchuk, I., Kovalchuk, O., Kozin, S., Kulminski, A., Lashmanova, E., Lezhnina, K., Liu, G. H., Longo, V., Mamoshina, P., Maslov, A., de Magalhaes, J. P., Mitchell, J., Mitnitski, A., Nikolsky, Y., Ozerov, I., Pasyukova, E., Peregudova, D., Popov, V., Proshkina, E., Putin, E., Rogaev, E., Rogina, B. & Zhumadilov, Z., Jan 1 2017, In : Aging. 9, 1, p. 7-25 19 p.

Research output: Contribution to journal › Article

10 Citations (Scopus)

Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan

Supiyev, A., Nurgozhin, T., Zhumadilov, Z., Peasey, A., Hubacek, J. A. & Bobak, M., Aug 11 2017, In : BMC Public Health. 17, 1, 1 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Risks for tuberculosis in Kazakhstan: Implications for prevention

Davis, A., Terlikbayeva, A., Aifah, A., Hermosilla, S., Zhumadilov, Z., Berikova, E., Rakhimova, S., Primbetova, S., Darisheva, M., Schluger, N. & El-Bassel, N., Jan 1 2017, In : International Journal of Tuberculosis and Lung Disease. 21, 1

Research output: Contribution to journal › Article

6 Citations (Scopus)

The effect of intraumbilical fetal nutrition via a subcutaneously implanted port system on amino acid concentration by severe IUGR human fetuses

Tchirikov, M., Zhumadilov, Z. S., Bapayeva, G., Bergner, M. & Entezami, M., Feb 1 2017, In : Journal of Perinatal Medicine. 45, 2, p. 227-236 10 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Treatment of Preterm Premature Rupture of Membranes with Oligo-/Anhydramnion Colonized by Multiresistant Bacteria with Continuous Amnioinfusion and Antibiotic Administrations through a Subcutaneously Implanted Intrauterine Port System: A Case Report

Tchirikov, M., Zhumadilov, Z., Winarno, A. S., Haase, R. & Buchmann, J., Jul 1 2017, In : Fetal Diagnosis and Therapy. 42, 1, p. 71-76 6 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)
2016

Diabetes prevalence, awareness and treatment and their correlates in older persons in urban and rural population in the Astana region, Kazakhstan

Supiyev, A., Kossumov, A., Kassenova, A., Nurgozhin, T., Zhumadilov, Z., Peasey, A. & Bobak, M., Feb 1 2016, In : Diabetes Research and Clinical Practice. 112, p. 6-12 7 p.

Research output: Contribution to journal › Article

Open Access
16 Citations (Scopus)

Fever as an important resource for infectious diseases research

Plaza, J. J. G., Hulak, N., Zhumadilov, Z. & Akilzhanova, A., Jan 1 2016, In : Intractable and Rare Diseases Research. 5, 2, p. 97-102 6 p.

Research output: Contribution to journal › Review article

5 Citations (Scopus)

Natural (tryptophan) metabolites-mediated activation of aryl hydrocarbon receptor inhibits cancer stem cell signaling: What does it mean to prevent cancer recurrence?

Xie, Y., Tokay, T., Zhumadilov, Z., Wu, D. & Zhang, J., Feb 1 2016, In : Translational Cancer Research. 5, 1, p. 64-67 4 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

nMet, a new target in recurrent cancer

Xie, Y., Istayeva, S., Chen, Z., Tokay, T., Zhumadilov, Z., Wu, D., Hortelano, G. & Zhang, J., Sep 1 2016, In : Current Cancer Drug Targets. 16, 7, p. 572-578 7 p.

Research output: Contribution to journal › Review article

4 Citations (Scopus)

Pim-1 kinase as cancer drug target: An update (Review)

Tursynbay, Y., Zhang, J., Li, Z., Tokay, T., Zhumadilov, Z., Wu, D. & Xie, Y., Feb 1 2016, In : Biomedical Reports. 4, 2, p. 140-146 7 p.

Research output: Contribution to journal › Review article

35 Citations (Scopus)

Risk factors for primary pulmonary TB in Almaty Region, Kazakhstan: A matched case-control study

Zhussupov, B., Hermosilla, S., Terlikbayeva, A., Aifah, A., Ma, X., Zhumadilov, Z., Abildayev, T., Darisheva, M. & Berikkhanova, K., Apr 27 2016, In : Iranian Journal of Public Health. 45, 4, p. 441-450 10 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Role of metabolism during viral infections, and crosstalk with the innate immune system

Plaza, J. J. G., Hulak, N., Kausova, G., Zhumadilov, Z. & Akilzhanova, A., Jan 1 2016, In : Intractable and Rare Diseases Research. 5, 2, p. 90-96 7 p.

Research output: Contribution to journal › Review article

11 Citations (Scopus)

Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2

Alimbetov, D., Davis, T., Brook, A. J. C., Cox, L. S., Faragher, R. G. A., Nurgozhin, T., Zhumadilov, Z. & Kipling, D., Apr 1 2016, In : Biogerontology. 17, 2, p. 305-315 11 p.

Research output: Contribution to journal › Article

36 Citations (Scopus)
2015

Deep phylogenetic analysis of haplogroup G1 provides estimates of SNP and STR mutation rates on the human Y-chromosome and reveals migrations of iranic speakers

Balanovsky, O., Zhabagin, M., Agdzhoyan, A., Chukhryaeva, M., Zaporozhchenko, V., Utevska, O., Highnam, G., Sabitov, Z., Greenspan, E., Dibirova, K., Skhalyakho, R., Kuznetsova, M., Koshel, S., Yusupov, Y., Nymadawa, P., Zhumadilov, Z., Pocheshkhova, E., Haber, M., Zalloua, P. A., Yepiskoposyan, L. & 3 others, Dybo, A., Tyler-Smith, C. & Balanovska, E., Apr 7 2015, In : PLoS ONE. 10, 4, e0122968.

Research output: Contribution to journal › Article

21 Citations (Scopus)

Diabetes prevalence, awareness and treatment and their correlates in older persons in urban and rural population in the Astana region, Kazakhstan

Kossumov, A., Supiyev, A., Nurgozhin, T., Zhumadilov, Z., Kassenova, A. & Peasey, A., Dec 12 2015, In : Diabetes Research and Clinical Practice. 112, -, p. 6-12 7 p., https://doi.org/10.1016/j.diabres.2015.11.011.

Research output: Contribution to journal › Article

Open Access

Draft genome sequence of Lactobacillus rhamnosus CLS17

Kozhakhmetov, S. S., Kushugulova, A. R., Saduakhasova, S. A., Shakhabayeva, G. S., Khassenbekova, Z. R., Molkenov, A. B., Kairov, U. E., Issayeva, R. B., Nurgozhin, T. S. & Zhumadilov, Z. S., 2015, In : Genome Announcements. 3, 3, e00478-15.

Research output: Contribution to journal › Article

Draft genome sequences of two clinical isolates of Mycobacterium tuberculosis from sputum of Kazakh patients

Kairov, U., Kozhamkulov, U., Molkenov, A., Rakhimova, S., Askapuli, A., Zhabagin, M., Akhmetova, A., Yerezhepov, D., Abilova, Z., Abilmazhinova, A., Bismilda, V., Chingisova, L., Zhumadilov, Z. & Akilzhanova, A., 2015, In : Genome Announcements. 3, 3, e00466-15.

Research output: Contribution to journal › Article

Gut microbiome diversity in kazakhstani women of different age groups

Baiskhanova, D., Kushugulova, A., Kozhakhmetov, S., Khassenbekova, Z., Nurgozhin, T., Marotta, F. & Zhumadilov, Z., 2015, In : International Journal of Probiotics and Prebiotics. p. 97-108 12 p.

Research output: Contribution to journal › Article

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1 Citation (Scopus)
37 Downloads (Pure)

Oesophageal squamous cell carcinoma (ESCC): Advances through omics technologies, towards ESCC salivaomics

González-Plaza, J. J. O., Hulak, N., García-Fuentes, E., Garrido-Sánchez, L., Zhumadilov, Z. & Akilzhanova, A., Aug 1 2015, In : Drug Discoveries and Therapeutics. 9, 4, p. 247-257 11 p.

Research output: Contribution to journal › Review article

Prevalence, awareness, treatment and control of arterial hypertension in Astana, Kazakhstan. A cross-sectional study

Supiyev, A., Kossumov, A., Utepova, L., Nurgozhin, T., Zhumadilov, Z. & Bobak, M., Jul 1 2015, In : Public Health. 129, 7, p. 948-953 6 p.

Research output: Contribution to journal › Article

13 Citations (Scopus)

Proteomic analysis of cellular response induced by boron neutron capture reaction in human squamous cell carcinoma SAS cells

Sato, A., Itoh, T., Imamichi, S., Kikuhara, S., Fujimori, H., Hirai, T., Saito, S., Sakurai, Y., Tanaka, H., Nakamura, H., Suzuki, M., Murakami, Y., Baiseitov, D., Berikkhanova, K., Zhumadilov, Z., Imahori, Y., Itami, J., Ono, K., Masunaga, S. & Masutani, M., Dec 1 2015, In : Applied Radiation and Isotopes. 106, p. 213-219 7 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

Red blood cell ghosts as promising drug carriers to target wound infections

Berikkhanova, K., Omarbaev, R., Gulyayev, A., Shulgau, Z., Ibrasheva, D., Adilgozhina, G., Sergazy, S., Zhumadilov, Z. & Askarova, S., Sep 23 2015, (Accepted/In press) In : Medical Engineering and Physics.

Research output: Contribution to journal › Article

5 Citations (Scopus)

Role of membrane biophysics in Alzheimer's-related cell pathways

Zhu, D., Bungart, B. L., Yang, X., Zhumadilov, Z., Lee, J. C. M. & Askarova, S., Jan 1 2015, In : Frontiers in Neuroscience. 9, MAY, 186.

Research output: Contribution to journal › Article

13 Citations (Scopus)

Tuberculosis report among injection drug users and their partners in Kazakhstan

Hermosilla, S., El-Bassel, N., Aifah, A., Terlikbayeva, A., Zhumadilov, Z., Berikkhanova, K., Darisheva, M., Gilbert, L., Schluger, N. & Galea, S., May 1 2015, In : Public Health. 129, 5, p. 569-575 7 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)
2014

Antioxidant activity of the probiotic consortium in vitro

Kushugulova, A., Saduakhasova, S., Kozhakhmetov, S., Shakhabayeva, G., Tynybayeva, I., Nurgozhin, T., Marotta, F. & Zhumadilov, Z., 2014, In : International Journal of Probiotics and Prebiotics. 9, 1-2, p. 55-60 6 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Erratum: (Anticancer Research (2014) 33:9 (4049))

Akilzhanova, A., Nurkina, Z., Momynaliev, K., Ramanculov, E., Zhumadilov, Z., Rakhypbekov, T., Hayashida, N., Nakashima, M. & Takamura, N., Jun 1 2014, In : Anticancer Research. 34, 6, 1 p.

Research output: Contribution to journal › Comment/debate

Expanding the metchnikoff postulate: Oral health is crucial in a successful global aging management strategy

Illuzzi, N., Galli, R., Kushugulova, A., Zhumadilov, Z., Licciardello, O. & Marotta, F., Apr 1 2014, In : Rejuvenation Research. 17, 2, p. 172-175 4 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Gut-targeted immunonutrition boosting natural killer cell activity using saccharomyces boulardii lysates in immuno-compromised healthy elderly subjects

Naito, Y., Marotta, F., Kantah, M. K., Zerbinati, N., Kushugulova, A., Zhumadilov, Z., Illuzzi, N., Sapienza, C., Takadanohara, H., Kobayashi, R. & Catanzaro, R., Apr 1 2014, In : Rejuvenation Research. 17, 2, p. 184-187 4 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Histological and biochemical analysis of DNA damage after BNCT in rat model

Masutani, M., Baiseitov, D., Itoh, T., Hirai, T., Berikkhanova, K., Murakami, Y., Zhumadilov, Z., Imahori, Y., Hoshi, M. & Itami, J., Jun 2014, In : Applied Radiation and Isotopes. 88, p. 104-108 5 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

Levels and distribution of self-rated health in the Kazakh population: Results from the Kazakhstan household health survey 2012

Supiyev, A., Nurgozhin, T., Zhumadilov, Z., Sharman, A., Marmot, M. & Bobak, M., Jul 30 2014, In : BMC Public Health. 14, 1, 768.

Research output: Contribution to journal › Review article

8 Citations (Scopus)

Pre-clinical evaluation of an adult extracorporeal carbon dioxide removal system with active mixing for pediatric respiratory support

Jeffries, R. G., Mussin, Y., Bulanin, D. S., Lund, L. W., Kocyildirim, E., Zhumadilov, Z. Z., Olzhayev, F. S., Federspiel, W. J. & Wearden, P. D., Jan 1 2014, In : International Journal of Artificial Organs. 37, 12, p. 888-899 12 p.

Research output: Contribution to journal › Article

4 Citations (Scopus)

RYR2 sequencing reveals novel missense mutations in a kazakh idiopathic ventricular tachycardia study cohort

Akilzhanova, A., Guelly, C., Nuralinov, O., Nurkina, Z., Nazhat, D., Smagulov, S., Tursunbekov, A., Alzhanova, A., Rashbayeva, G., Abdrakhmanov, A., Dosmagambet, S., Trajanoski, S., Zhumadilov, Z., Sharman, A. & Bekbosynova, M., Jun 30 2014, In : PLoS ONE. 9, 6, e101059.

Research output: Contribution to journal › Article

2 Citations (Scopus)
2013

Biomarkers, interventions and healthy ageing

Kenessary, A., Zhumadilov, Z., Nurgozhin, T., Kipling, D., Yeoman, M., Cox, L., Ostler, E. & Faragher, R., May 25 2013, In : New Biotechnology. 30, 4, p. 373-377 5 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

Effect of celergen, a marine derivative, on in vitro hepatocarcinogenesis

Catanzaro, R., Zerbinati, N., Solimene, U., Celep, G., Marotta, F., Kushugulova, A., Milazzo, M., Tomella, C., Bertuccelli, G. & Zhumadilov, Z., 2013, In : Drug Discoveries and Therapeutics. 7, 5, p. 196-200 5 p.

Research output: Contribution to journal › Article

ESR dosimetry study of population in the vicinity of the Semipalatinsk Nuclear Test Site

Zhumadilov, K., Ivannikov, A., Stepanenko, V., Zharlyganova, D., Toyoda, S., Zhumadilov, Z. & Hoshi, M., Jan 1 2013, In : Journal of Radiation Research. 54, 4, p. 775-779 5 p.

Research output: Contribution to journal › Article

Open Access
4 Citations (Scopus)

Genetic profile and determinants of homocysteine levels in Kazakhstan patients with breast cancer

Akilzhanova, A., Nurkina, Z., Momynaliev, K., Ramanculov, E., Zhumadilov, Z., Rakhypbekov, T., Hayashida, N., Nakashima, M. & Takamura, N., Sep 1 2013, In : Anticancer Research. 33, 9, p. 4049-4060 12 p.

Research output: Contribution to journal › Article

18 Citations (Scopus)

Global initiative for interdisciplinary approach to improve innovative clinical research and treatment outcomes in geriatrics: Biological cell-based targeted drug delivery systems for geriatrics

Zhumadilov, Z., Jun 1 2013, In : Rejuvenation Research. 16, 3, p. 212-223 12 p.

Research output: Contribution to journal › Review article

4 Citations (Scopus)

Isolation and characterization of lactobacilli from traditional Kazakh dairy products

Kushugulova, A., Kozhakhmetov, S., Supiyev, A., Shakhabayeva, G., Saduakhasova, S., Sabitkyzy, S., Gulayev, A., Nurgozhin, T., Zhumadilov, Z. & Sharman, A., Jan 1 2013, In : International Journal of Probiotics and Prebiotics. 8, 2-3, p. 95-99 5 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Treatment of PPROM with anhydramnion in humans: First experience with different amniotic fluid substitutes for continuous amnioinfusion through a subcutaneously implanted port system

Tchirikov, M., Bapayeva, G., Zhumadilov, Z. S., Dridi, Y., Harnisch, R. & Herrmann, A., Dec 4 2013, In : Journal of Perinatal Medicine. 41, 6, p. 657-663 7 p.

Research output: Contribution to journal › Article

7 Citations (Scopus)
2012

Cytisin amidophosphate - The new cytoprotector

Zhumadilov, Z., Nurgozhin, T., Gulyaev, A., Zhaugasheva, S., Gazaliyev, A., Ermekbayeva, B., Abuova, G. & Kenessary, A., Sep 1 2012, In : Hiroshima Journal of Medical Sciences. 61, 3, p. 45-49 5 p.

Research output: Contribution to journal › Article

Interview with Zhaxybay Zhumadilov, M.D., Ph.D. Interview by Vicki Glaser.

Zhumadilov, Z., Jun 2012, In : Rejuvenation research. 15, 3, p. 339-342 4 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Scientific excellence in biomedical research: New opportunities and challenges in Kazakhstan

Zhumadilov, Z., Apr 1 2012, In : Rejuvenation Research. 15, 2, p. 249-251 3 p.

Research output: Contribution to journal › Article

3 Citations (Scopus)

Tuberculosis in Kazakhstan: Analysis of risk determinants in national surveillance data

Terlikbayeva, A., Hermosilla, S., Galea, S., Schluger, N., Yegeubayeva, S., Abildayev, T., Muminov, T., Akiyanova, F., Bartkowiak, L., Zhumadilov, Z., Sharman, A. & El-Bassel, N., Oct 18 2012, In : BMC Infectious Diseases. 12, 262.

Research output: Contribution to journal › Article

14 Citations (Scopus)
2011

Behavior and food consumption pattern of the population exposed in 1949-1962 to fallout from Semipalatinsk nuclear test site in Kazakhstan

Drozdovitch, V., Schonfeld, S., Akimzhanov, K., Aldyngurov, D., Land, C. E., Luckyanov, N., Mabuchi, K., Potischman, N., Schwerin, M. J., Semenova, Y., Tokaeva, A., Zhumadilov, Z., Bouville, A. & Simon, S. L., Mar 1 2011, In : Radiation and Environmental Biophysics. 50, 1, p. 91-103 13 p.

Research output: Contribution to journal › Article

8 Citations (Scopus)

ESR dosimetry study for the residents of Kazakhstan exposed to radioactive fallout on 24, August 1956

Zhumadilov, K., Ivannikov, A., Zharlyganova, D., Zhumadilov, Z., Stepanenko, V., Abralina, S., Sadvokasova, L., Zhumadilova, A., Toyoda, S., Endo, S., Okamoto, T. & Hoshi, M., Sep 1 2011, In : Radiation Measurements. 46, 9, p. 793-796 4 p.

Research output: Contribution to journal › Article

4 Citations (Scopus)