A multiphase approach to model blood flow in micro-tubes

T. M. Mubita, L. R. Rojas-Solórzano, J. B. Moreno

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The development of micro-fluidic devices to support the systemic circulation of blood has been used either as a temporary bridge or as a recovery method to treat different heart diseases. Blood flow through these artificial micro-channels is a major challenge because blood at scales from tens to hundreds of microns behaves as a multiphase suspension of deformable particles. A homogeneous model of blood is not adequate if the effect of cell segregation through these devices is of interest to evaluate blood cell damage (e.g., hemolysis or thrombosis). To determine the flow field and model the occurrence of segregation, an Eulerian frame of reference is employed. The simulations are performed in a tube of internal diameter of 217 µm. We find that the results contribute to improve the understanding of the fluid dynamics of blood as a multi-component medium. Our simulations are based on an alternative methodology for blood modelling at a lower computational cost compared to DNS.

Original languageEnglish
Title of host publicationComputational and Experimental Fluid Mechanics with Applications to Physics, Engineering and the Environment, FLUIDOS 2012
EditorsLeonardo Di G. Sigalotti, Eloy Sira, Jaime Klapp
PublisherSpringer
Pages235-247
Number of pages13
ISBN (Print)9783319001906
DOIs
Publication statusPublished - 2014
Event1st Workshop of the Venezuelan Society of Fluid Mechanics , FLUIDOS 2012 - Margarita Island, Venezuela, Bolivarian Republic of
Duration: Nov 5 2012Nov 9 2012

Publication series

NameEnvironmental Science and Engineering
ISSN (Print)1863-5520
ISSN (Electronic)1863-5539

Conference

Conference1st Workshop of the Venezuelan Society of Fluid Mechanics , FLUIDOS 2012
CountryVenezuela, Bolivarian Republic of
City Margarita Island
Period11/5/1211/9/12

ASJC Scopus subject areas

  • Environmental Engineering
  • Information Systems

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