A transient post-translational modification of active site cysteine alters binding properties of the parkinsonism protein DJ-1

Medicine & Life Sciences

• Protein Deglycase DJ-1 100%
• Parkinsonian Disorders 65%
• human PARK7 protein 64%
• Post Translational Protein Processing 61%
• Sulfinic Acids 56%
• Cysteine 56%
• Sulfenic Acids 55%
• Catalytic Domain 53%
• Color 49%
• polyhistidine 47%
• X Ray Crystallography 40%
• imidazole 38%
• Oxidants 31%
• Serine 28%
• Parkinson Disease 24%
• Mutation 16%
• Proteins 10%

Chemical Compounds

• Cysteine 51%
• Column Like Crystal 35%
• Modification 33%
• Blue 28%
• Sulfenic Acid 28%
• Sulfinic Acid 27%
• Carboxymethylation 27%
• Protein 24%
• Cysteine Residue 20%
• Serine 18%
• Imidazole 17%
• Mutation 16%
• Protective 16%
• X-Ray Crystallography 16%
• Adduct 14%
• Metabolite 13%
• Oxidation Reaction 8%