Active transport of proteins into the nucleus

Philipp Wagner, Jeannette Kunz, Antonius Koller, Michael N. Hall

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)

Abstract

Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalFEBS Letters
Volume275
Issue number1-2
DOIs
Publication statusPublished - Nov 26 1990

Keywords

  • Nuclear localization signal
  • Nuclear pore complex

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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