Active transport of proteins into the nucleus

Philipp Wagner, Jeannette Kunz, Antonius Koller, Michael N. Hall

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalFEBS Letters
Volume275
Issue number1-2
DOIs
Publication statusPublished - Nov 26 1990
Externally publishedYes

Fingerprint

Active Biological Transport
Nuclear Envelope
Nuclear Proteins
Carrier Proteins
Nuclear Pore
Nuclear Localization Signals

Keywords

  • Nuclear localization signal
  • Nuclear pore complex

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Active transport of proteins into the nucleus. / Wagner, Philipp; Kunz, Jeannette; Koller, Antonius; Hall, Michael N.

In: FEBS Letters, Vol. 275, No. 1-2, 26.11.1990, p. 1-5.

Research output: Contribution to journalArticle

Wagner, Philipp ; Kunz, Jeannette ; Koller, Antonius ; Hall, Michael N. / Active transport of proteins into the nucleus. In: FEBS Letters. 1990 ; Vol. 275, No. 1-2. pp. 1-5.
@article{9ecb2772f05f455398f48639202870ec,
title = "Active transport of proteins into the nucleus",
abstract = "Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.",
keywords = "Nuclear localization signal, Nuclear pore complex",
author = "Philipp Wagner and Jeannette Kunz and Antonius Koller and Hall, {Michael N.}",
year = "1990",
month = "11",
day = "26",
doi = "10.1016/0014-5793(90)81425-N",
language = "English",
volume = "275",
pages = "1--5",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Active transport of proteins into the nucleus

AU - Wagner, Philipp

AU - Kunz, Jeannette

AU - Koller, Antonius

AU - Hall, Michael N.

PY - 1990/11/26

Y1 - 1990/11/26

N2 - Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.

AB - Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.

KW - Nuclear localization signal

KW - Nuclear pore complex

UR - http://www.scopus.com/inward/record.url?scp=0024990707&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024990707&partnerID=8YFLogxK

U2 - 10.1016/0014-5793(90)81425-N

DO - 10.1016/0014-5793(90)81425-N

M3 - Article

VL - 275

SP - 1

EP - 5

JO - FEBS Letters

JF - FEBS Letters

SN - 0014-5793

IS - 1-2

ER -