Active transport of proteins into the nucleus

Philipp Wagner, Jeannette Kunz, Antonius Koller, Michael N. Hall

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Nuclear proteins are actively and posttranslationally transported across the nuclear envelope. This transport is highly selective process that can be divided into two steps, receptor-binding followed by translocation through the nuclear envelope. Receptor-binding is mediated by nuclear localization signals that have been identified in many nuclear proteins. Translocation is energy-dependent and occurs through the nuclear pore complex.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalFEBS Letters
Volume275
Issue number1-2
DOIs
Publication statusPublished - Nov 26 1990

Keywords

  • Nuclear localization signal
  • Nuclear pore complex

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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