Adhesion molecules: Opportunities for modulation and a paradigm for novel therapeutic approaches in cancer

I. El-Hariry, M. Pignatelli

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

In the past decade, there have been major advances in the elucidation of processes underlying tumour invasion and metastasis, in which adhesion molecules play a critical role. These advances have revolutionised our ability to devise novel approaches for cancer treatment. This review gives an insight into the adhesion pathways, and highlights the current status of adhesion molecules as potential therapeutic targets.

Original languageEnglish
Pages (from-to)1465-1478
Number of pages14
JournalExpert Opinion on Investigational Drugs
Volume6
Issue number10
DOIs
Publication statusPublished - Oct 21 1997

Keywords

  • Adhesion molecules
  • Cancer therapy
  • Metastasis
  • Tumour invasion

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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