Abstract
In the past decade, there have been major advances in the elucidation of processes underlying tumour invasion and metastasis, in which adhesion molecules play a critical role. These advances have revolutionised our ability to devise novel approaches for cancer treatment. This review gives an insight into the adhesion pathways, and highlights the current status of adhesion molecules as potential therapeutic targets.
| Original language | English |
|---|---|
| Pages (from-to) | 1465-1478 |
| Number of pages | 14 |
| Journal | Expert Opinion on Investigational Drugs |
| Volume | 6 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1997 |
| Externally published | Yes |
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Keywords
- Adhesion molecules
- Cancer therapy
- Metastasis
- Tumour invasion
ASJC Scopus subject areas
- Pharmacology
Cite this
Adhesion molecules : Opportunities for modulation and a paradigm for novel therapeutic approaches in cancer. / El-Hariry, I.; Pignatelli, M.
In: Expert Opinion on Investigational Drugs, Vol. 6, No. 10, 1997, p. 1465-1478.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adhesion molecules
T2 - Opportunities for modulation and a paradigm for novel therapeutic approaches in cancer
AU - El-Hariry, I.
AU - Pignatelli, M.
PY - 1997
Y1 - 1997
N2 - In the past decade, there have been major advances in the elucidation of processes underlying tumour invasion and metastasis, in which adhesion molecules play a critical role. These advances have revolutionised our ability to devise novel approaches for cancer treatment. This review gives an insight into the adhesion pathways, and highlights the current status of adhesion molecules as potential therapeutic targets.
AB - In the past decade, there have been major advances in the elucidation of processes underlying tumour invasion and metastasis, in which adhesion molecules play a critical role. These advances have revolutionised our ability to devise novel approaches for cancer treatment. This review gives an insight into the adhesion pathways, and highlights the current status of adhesion molecules as potential therapeutic targets.
KW - Adhesion molecules
KW - Cancer therapy
KW - Metastasis
KW - Tumour invasion
UR - http://www.scopus.com/inward/record.url?scp=0030764028&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030764028&partnerID=8YFLogxK
U2 - 10.1517/13543784.6.10.1465
DO - 10.1517/13543784.6.10.1465
M3 - Article
C2 - 15989513
AN - SCOPUS:0030764028
VL - 6
SP - 1465
EP - 1478
JO - Expert Opinion on Investigational Drugs
JF - Expert Opinion on Investigational Drugs
SN - 1354-3784
IS - 10
ER -