All-fiber label-free optical fiber biosensors: from modern technologies to current applications [Invited]

Aliya Bekmurzayeva, Marzhan Nurlankyzy, Albina Abdossova, Zhuldyz Myrkhiyeva, Daniele Tosi

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Biosensors are established as promising analytical tools for detecting various analytes important in biomedicine and environmental monitoring. Using fiber optic technology as a sensing element in biosensors offers low cost, high sensitivity, chemical inertness, and immunity to electromagnetic interference. Optical fiber sensors can be used in in vivo applications and multiplexed to detect several targets simultaneously. Certain configurations of optical fiber technology allow the detection of analytes in a label-free manner. This review aims to discuss recent advances in label-free optical fiber biosensors from a technological and application standpoint. First, modern technologies used to build label-free optical fiber-based sensors will be discussed. Then, current applications where these technologies are applied are elucidated. Namely, examples of detecting soluble cancer biomarkers, hormones, viruses, bacteria, and cells are presented.

Original languageEnglish
Pages (from-to)1453-1473
Number of pages21
JournalBiomedical Optics Express
Volume15
Issue number3
DOIs
Publication statusPublished - Mar 1 2024

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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