Abstract
Databases and computational tools are increasingly important in the study of allergies, particularly in the assessment of allergenicity and allergic cross-reactivity. ALLERDB database contains sequences of allergens and information on reported cross-reactivity between allergens. It focuses on analysis of allergenicity and allergic cross-reactivity of clinically relevant protein allergens. The official IUIS allergen data were extracted from the IUIS Allergen Nomenclature Sub-Committee website, and their sequence information from the public databases, and reference publications. The analysis tools assist allergen data analysis and retrieval, and include keyword searching, BLAST, prediction of allergenicity, modification of BLAST that displays cross-reactive allergens, and graphics representation of cross-reactivity data. ALLERDB is new brand of allergen databases with a rich set of tools for sequence comparison, pattern identification, and visualization of results. It is accessible at http://research.i2r.a-star.edu.sg/Templar/DB/Allergen.
| Original language | English |
|---|---|
| Pages (from-to) | 90-96 |
| Number of pages | 7 |
| Journal | Cellular Immunology |
| Volume | 244 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Dec 2006 |
| Externally published | Yes |
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Keywords
- Allergen nomenclature
- Allergenicity
- Allergic cross-reactivity
- FAO/WHO decision tree
ASJC Scopus subject areas
- Cell Biology
- Immunology
Cite this
ALLERDB database and integrated bioinformatic tools for assessment of allergenicity and allergic cross-reactivity. / Zhang, Zong Hong; Tan, Stephanie C C; Koh, Judice L Y; Falus, András; Brusic, Vladimir.
In: Cellular Immunology, Vol. 244, No. 2, 12.2006, p. 90-96.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - ALLERDB database and integrated bioinformatic tools for assessment of allergenicity and allergic cross-reactivity
AU - Zhang, Zong Hong
AU - Tan, Stephanie C C
AU - Koh, Judice L Y
AU - Falus, András
AU - Brusic, Vladimir
PY - 2006/12
Y1 - 2006/12
N2 - Databases and computational tools are increasingly important in the study of allergies, particularly in the assessment of allergenicity and allergic cross-reactivity. ALLERDB database contains sequences of allergens and information on reported cross-reactivity between allergens. It focuses on analysis of allergenicity and allergic cross-reactivity of clinically relevant protein allergens. The official IUIS allergen data were extracted from the IUIS Allergen Nomenclature Sub-Committee website, and their sequence information from the public databases, and reference publications. The analysis tools assist allergen data analysis and retrieval, and include keyword searching, BLAST, prediction of allergenicity, modification of BLAST that displays cross-reactive allergens, and graphics representation of cross-reactivity data. ALLERDB is new brand of allergen databases with a rich set of tools for sequence comparison, pattern identification, and visualization of results. It is accessible at http://research.i2r.a-star.edu.sg/Templar/DB/Allergen.
AB - Databases and computational tools are increasingly important in the study of allergies, particularly in the assessment of allergenicity and allergic cross-reactivity. ALLERDB database contains sequences of allergens and information on reported cross-reactivity between allergens. It focuses on analysis of allergenicity and allergic cross-reactivity of clinically relevant protein allergens. The official IUIS allergen data were extracted from the IUIS Allergen Nomenclature Sub-Committee website, and their sequence information from the public databases, and reference publications. The analysis tools assist allergen data analysis and retrieval, and include keyword searching, BLAST, prediction of allergenicity, modification of BLAST that displays cross-reactive allergens, and graphics representation of cross-reactivity data. ALLERDB is new brand of allergen databases with a rich set of tools for sequence comparison, pattern identification, and visualization of results. It is accessible at http://research.i2r.a-star.edu.sg/Templar/DB/Allergen.
KW - Allergen nomenclature
KW - Allergenicity
KW - Allergic cross-reactivity
KW - FAO/WHO decision tree
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U2 - 10.1016/j.cellimm.2007.01.007
DO - 10.1016/j.cellimm.2007.01.007
M3 - Article
VL - 244
SP - 90
EP - 96
JO - Cellular Immunology
JF - Cellular Immunology
SN - 0008-8749
IS - 2
ER -