Abstract
Despite dramatic declines in HIV-associated morbidity and mortality as a result of highly active antiretroviral therapy, management of heavily treatment-experienced patients remains complex and challenging. Treatment response rates with subsequent antiretroviral regimens are lower than with initial antiretroviral therapy. Additionally, increased mortality has been associated with multidrug-resistant HIV. We review data relevant to management of such patients and offer a systematic approach to constructing a salvage antiretroviral regimen.
| Original language | English |
|---|---|
| Pages (from-to) | 496-507 |
| Number of pages | 12 |
| Journal | Lancet Infectious Diseases |
| Volume | 6 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 1 2006 |
ASJC Scopus subject areas
- Infectious Diseases
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Temesgen, Z., Cainelli, F., Poeschla, E. M., Vlahakis, S. AR., & Vento, S. (2006). Approach to salvage antiretroviral therapy in heavily antiretroviral-experienced HIV-positive adults. Lancet Infectious Diseases, 6(8), 496-507. https://doi.org/10.1016/S1473-3099(06)70550-3