Autism and Gut–Brain Axis: Role of Probiotics

Saravana Babu Chidambaram; Sunanda Tuladhar; Abid Bhat; Arehally Marappa Mahalakshmi; Bipul Ray; Musthafa Mohamed Essa; Muhammed Bishir; Srinivasa Rao Bolla; Nandakumar Dalavaikodihalli Nanjaiah; Gilles J. Guillemin; M. Walid Qoronfleh

doi:10.1007/978-3-030-30402-7_21

Autism and Gut–Brain Axis: Role of Probiotics

Saravana Babu Chidambaram, Sunanda Tuladhar, Abid Bhat, Arehally Marappa Mahalakshmi, Bipul Ray, Musthafa Mohamed Essa, Muhammed Bishir, Srinivasa Rao Bolla, Nandakumar Dalavaikodihalli Nanjaiah, Gilles J. Guillemin, M. Walid Qoronfleh

Research output: Chapter in Book/Report/Conference proceeding › Chapter

20 Citations (Scopus)

Abstract

Characterized by a wide range of behavioural, social and language problems, autism is a complex developmental disability that affects an individual’s capacity to communicate and interact with others. Although the real causes that lead to the development of autism are still unclear, the gastrointestinal tract has been found to play a major role in the development of autism. Alterations in macrobiotic compositions have been reported in autistic children. Irregularities in carbohydrate digestion and absorption could also explain some of the gastrointestinal problems reported in autistic patients, although their role in the neurological and behavioural problems remains uncertain. A relationship between improved gut health and decrease of symptoms in autism has been reported as well. Studies done to evaluate the gluten-free diets, casein-free diets, pre- and probiotic and multivitamin supplementation have shown promising results. Probiotics have been thought to alleviate the progression of autism and reduce cognitive and behavioural deficits.

Original language	English
Title of host publication	Advances in Neurobiology
Publisher	Springer
Pages	587-600
Number of pages	14
DOIs	https://doi.org/10.1007/978-3-030-30402-7_21
Publication status	Published - Jan 1 2020
Externally published	Yes

Publication series

Name	Advances in Neurobiology
Volume	24
ISSN (Print)	2190-5215
ISSN (Electronic)	2190-5223

Keywords

ASD
Autism
Barrier pathway
Cognitive and behavioural deficits
GI dysfunction
Gut–brain axis
Microbiome
Probiotics

ASJC Scopus subject areas

Biochemistry
Neurology
Developmental Neuroscience
Cellular and Molecular Neuroscience

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10.1007/978-3-030-30402-7_21

Cite this

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abstract = "Characterized by a wide range of behavioural, social and language problems, autism is a complex developmental disability that affects an individual{\textquoteright}s capacity to communicate and interact with others. Although the real causes that lead to the development of autism are still unclear, the gastrointestinal tract has been found to play a major role in the development of autism. Alterations in macrobiotic compositions have been reported in autistic children. Irregularities in carbohydrate digestion and absorption could also explain some of the gastrointestinal problems reported in autistic patients, although their role in the neurological and behavioural problems remains uncertain. A relationship between improved gut health and decrease of symptoms in autism has been reported as well. Studies done to evaluate the gluten-free diets, casein-free diets, pre- and probiotic and multivitamin supplementation have shown promising results. Probiotics have been thought to alleviate the progression of autism and reduce cognitive and behavioural deficits.",

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AU - Mahalakshmi, Arehally Marappa

AU - Ray, Bipul

AU - Essa, Musthafa Mohamed

AU - Bishir, Muhammed

AU - Bolla, Srinivasa Rao

AU - Nanjaiah, Nandakumar Dalavaikodihalli

AU - Guillemin, Gilles J.

AU - Qoronfleh, M. Walid

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AB - Characterized by a wide range of behavioural, social and language problems, autism is a complex developmental disability that affects an individual’s capacity to communicate and interact with others. Although the real causes that lead to the development of autism are still unclear, the gastrointestinal tract has been found to play a major role in the development of autism. Alterations in macrobiotic compositions have been reported in autistic children. Irregularities in carbohydrate digestion and absorption could also explain some of the gastrointestinal problems reported in autistic patients, although their role in the neurological and behavioural problems remains uncertain. A relationship between improved gut health and decrease of symptoms in autism has been reported as well. Studies done to evaluate the gluten-free diets, casein-free diets, pre- and probiotic and multivitamin supplementation have shown promising results. Probiotics have been thought to alleviate the progression of autism and reduce cognitive and behavioural deficits.

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KW - Barrier pathway

KW - Cognitive and behavioural deficits

KW - GI dysfunction

KW - Gut–brain axis

KW - Microbiome

KW - Probiotics

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Autism and Gut–Brain Axis: Role of Probiotics

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Keywords

ASJC Scopus subject areas

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