Bench-Stable Cobalt Pre-Catalysts for Mild Hydrosilative Reduction of Tertiary Amides to Amines and Beyond

Alibek Nurseiit, Jaysan Janabel, Kristina Gudun, Aishabibi Kassymbek, Medet Segizbayev, Tulegen Seilkhanov, Andrey Khalimon

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

The readily synthesized and bench‐stable cobalt dichloride complex (dpephos)CoCl2 is employed as a pre‐catalyst for a diversity of silane additions to unsaturated organic molecules, including the normally challenging reduction of amides to amines. With regard to hydrosilative reduction of amides even more effective and activator free catalytic systems can be generated from the bench‐stable, commercially available Co(acac)2 and Co(OAc)2 with dpephos and PPh3 ligands. These systems operate under mild conditions (<100 °C), with many examples of room temperature transformations, presenting a first example of mild cobalt‐catalyzed hydrosilylation of amides
Original languageEnglish
Article number10.1002/cctc.201801605
Pages (from-to)790-798
Number of pages9
JournalChemCatChem
Volume11
Issue number2
DOIs
Publication statusPublished - Jan 2019

Keywords

  • Cobalt
  • hydrosilylation
  • amides
  • homogeneous catalysis

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