Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases

Keyphrases

• Neutrophil Elastase 100%
• Proteolytic Activity 100%
• Camostat 100%
• Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) 60%
• COVID-19 40%
• SARS-CoV-2 Spike Protein 40%
• Cathepsin G 40%
• Proteinase 3 40%
• Transmembrane Protease 40%
• Catalytic Activity 40%
• Serine Protease Inhibitor 40%
• Comorbidity 20%
• Cardiovascular Disease 20%
• Immune Response 20%
• Autoimmunity 20%
• Productive Infection 20%
• Viral Replication 20%
• Neutrophils 20%
• Immune Cells 20%
• Host Cell 20%
• Furin Protease 20%
• Cell-to-cell Transmission 20%
• Spike Protein 20%
• Angiotensin-converting Enzyme 2 (ACE2) 20%
• Infection Site 20%
• Chronic Inflammatory Diseases 20%
• Trypsin-like 20%
• Severe Coronavirus Disease 2019 20%
• Cardiovascular Thrombosis 20%
• Proteolytic Digestion 20%
• Severe Outcomes 20%
• Multiple Organ Failure 20%
• Cytosol 20%

Biochemistry, Genetics and Molecular Biology

• Protein Catabolism 100%
• Serine Protease 100%
• SARS Coronavirus 80%
• Coronavirinae 60%
• Proteinase 3 40%
• Neutrophil Elastase 40%
• Serine Protease Inhibitor 40%
• Cathepsin G 40%
• Vitronectin 40%
• Myeloblastin 40%
• Enzymatic Activity 40%
• Immunocompetent Cell 20%
• Immune Response 20%
• Angiotensin-Converting Enzyme 2 20%
• Virus Replication 20%
• Autoimmunity 20%
• Furin 20%
• Comorbidity 20%
• Spike Protein 20%

INIS

• serine 100%
• neutrophils 100%
• coronaviruses 57%
• diseases 42%
• proteins 42%
• cathepsin 28%
• risks 14%
• morbidity 14%
• transmission 14%
• failures 14%
• inflammation 14%
• organs 14%
• host 14%
• cardiovascular diseases 14%
• digestion 14%
• enzymes 14%
• thrombosis 14%
• angiotensin 14%
• trypsin 14%