Carbon dots doped with barium as a novel contrast agent for efficient CT X-ray attenuation

Anara Molkenova; Meruyert Kairova; Ainur Zhussupbekova; Kuanysh Zhussupbekov; Bakyt Duisenbayeva; Igor V. Shvets; Timur Sh Atabaev

doi:10.1016/j.nanoso.2022.100839

Carbon dots doped with barium as a novel contrast agent for efficient CT X-ray attenuation

Anara Molkenova, Meruyert Kairova, Ainur Zhussupbekova, Kuanysh Zhussupbekov, Bakyt Duisenbayeva, Igor V. Shvets, Timur Sh Atabaev

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The development of novel radiological contrast agents based on carbon dots (CDs) is attracting substantial interest because of their unique properties, such as biocompatibility, fabrication simplicity, colloidal stability and low cost. In this communication, the suitability of barium-doped carbon dots (Ba-CDs) for computed tomography (CT) X-ray attenuation has been assessed for the first time. Morphological analysis showed that Ba-CDs are quasi-spherical in shape with a mean particle size of ∼7.8 ± 2.3 nm. Chemical analysis revealed that the Ba(II) ion concentration in the Ba-CDs was ∼1.15 at%. The prepared Ba-CDs exhibit excellent fluorescent properties and good X-ray attenuation efficiency (13.2 ± 0.51 HU/mM), suggesting their potential applicability as an effective CT radiological contrast agent.

Original language	English
Article number	100839
Journal	Nano-Structures and Nano-Objects
Volume	29
DOIs	https://doi.org/10.1016/j.nanoso.2022.100839
Publication status	Published - Feb 2022

Keywords

Carbon dots
Computed tomography
Fluorescence
X-ray attenuation

ASJC Scopus subject areas

General Materials Science
Physical and Theoretical Chemistry
Atomic and Molecular Physics, and Optics
Condensed Matter Physics

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10.1016/j.nanoso.2022.100839

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title = "Carbon dots doped with barium as a novel contrast agent for efficient CT X-ray attenuation",

abstract = "The development of novel radiological contrast agents based on carbon dots (CDs) is attracting substantial interest because of their unique properties, such as biocompatibility, fabrication simplicity, colloidal stability and low cost. In this communication, the suitability of barium-doped carbon dots (Ba-CDs) for computed tomography (CT) X-ray attenuation has been assessed for the first time. Morphological analysis showed that Ba-CDs are quasi-spherical in shape with a mean particle size of ∼7.8 ± 2.3 nm. Chemical analysis revealed that the Ba(II) ion concentration in the Ba-CDs was ∼1.15 at%. The prepared Ba-CDs exhibit excellent fluorescent properties and good X-ray attenuation efficiency (13.2 ± 0.51 HU/mM), suggesting their potential applicability as an effective CT radiological contrast agent.",

keywords = "Carbon dots, Computed tomography, Fluorescence, X-ray attenuation",

author = "Anara Molkenova and Meruyert Kairova and Ainur Zhussupbekova and Kuanysh Zhussupbekov and Bakyt Duisenbayeva and Shvets, {Igor V.} and Atabaev, {Timur Sh}",

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AU - Molkenova, Anara

AU - Kairova, Meruyert

AU - Zhussupbekova, Ainur

AU - Zhussupbekov, Kuanysh

AU - Duisenbayeva, Bakyt

AU - Shvets, Igor V.

AU - Atabaev, Timur Sh

PY - 2022/2

Y1 - 2022/2

N2 - The development of novel radiological contrast agents based on carbon dots (CDs) is attracting substantial interest because of their unique properties, such as biocompatibility, fabrication simplicity, colloidal stability and low cost. In this communication, the suitability of barium-doped carbon dots (Ba-CDs) for computed tomography (CT) X-ray attenuation has been assessed for the first time. Morphological analysis showed that Ba-CDs are quasi-spherical in shape with a mean particle size of ∼7.8 ± 2.3 nm. Chemical analysis revealed that the Ba(II) ion concentration in the Ba-CDs was ∼1.15 at%. The prepared Ba-CDs exhibit excellent fluorescent properties and good X-ray attenuation efficiency (13.2 ± 0.51 HU/mM), suggesting their potential applicability as an effective CT radiological contrast agent.

AB - The development of novel radiological contrast agents based on carbon dots (CDs) is attracting substantial interest because of their unique properties, such as biocompatibility, fabrication simplicity, colloidal stability and low cost. In this communication, the suitability of barium-doped carbon dots (Ba-CDs) for computed tomography (CT) X-ray attenuation has been assessed for the first time. Morphological analysis showed that Ba-CDs are quasi-spherical in shape with a mean particle size of ∼7.8 ± 2.3 nm. Chemical analysis revealed that the Ba(II) ion concentration in the Ba-CDs was ∼1.15 at%. The prepared Ba-CDs exhibit excellent fluorescent properties and good X-ray attenuation efficiency (13.2 ± 0.51 HU/mM), suggesting their potential applicability as an effective CT radiological contrast agent.

KW - Carbon dots

KW - Computed tomography

KW - Fluorescence

KW - X-ray attenuation

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JF - Nano-Structures and Nano-Objects

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Carbon dots doped with barium as a novel contrast agent for efficient CT X-ray attenuation

Abstract

Keywords

ASJC Scopus subject areas

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