Carbon Dots Doped with Dysprosium: A Bimodal Nanoprobe for MRI and Fluorescence Imaging

Research output: Contribution to journalArticle

Abstract

In recent years, functional nanoprobes with multiple imaging modalities have become an emerging field of biomedical research. In this preliminary study, we utilized a facile hydrothermal method for the preparation of magneto-fluorescent bimodal carbon dots doped with dysprosium (Dy-CDs). The prepared Dy-CDs have shown a good colloidal stability in a water solution and strong blue⁻green fluorescence, with a maximum at 452 nm. In addition, the excellent transverse relaxivity of the prepared Dy-CDs (r₂ = 7.42 ± 0.07 mM-1s-1) makes them also suitable for T₂-weighted magnetic resonance imaging (MRI). Thus, synthesized Dy-CDs could be potentially utilized for both MRI and fluorescence imaging of living cells.

Original languageEnglish
Article number35
JournalJournal of Functional Biomaterials
Volume9
Issue number2
DOIs
Publication statusPublished - May 18 2018
Externally publishedYes

Fingerprint

Dysprosium
Nanoprobes
Magnetic resonance
Carbon
Fluorescence
Imaging techniques
Cells
Water

Keywords

  • Carbon dots
  • dysprosium
  • bimodal nanoprobes
  • fluorescence
  • magnetic resonance imaging MRI

Cite this

Carbon Dots Doped with Dysprosium: A Bimodal Nanoprobe for MRI and Fluorescence Imaging. / Atabaev, Timur Sh; Piao, Zhonglie; Molkenova, Anara.

In: Journal of Functional Biomaterials, Vol. 9, No. 2, 35, 18.05.2018.

Research output: Contribution to journalArticle

@article{73c56029d6684764befe22ef47e7871e,
title = "Carbon Dots Doped with Dysprosium: A Bimodal Nanoprobe for MRI and Fluorescence Imaging",
abstract = "In recent years, functional nanoprobes with multiple imaging modalities have become an emerging field of biomedical research. In this preliminary study, we utilized a facile hydrothermal method for the preparation of magneto-fluorescent bimodal carbon dots doped with dysprosium (Dy-CDs). The prepared Dy-CDs have shown a good colloidal stability in a water solution and strong blue⁻green fluorescence, with a maximum at 452 nm. In addition, the excellent transverse relaxivity of the prepared Dy-CDs (r₂ = 7.42 ± 0.07 mM-1s-1) makes them also suitable for T₂-weighted magnetic resonance imaging (MRI). Thus, synthesized Dy-CDs could be potentially utilized for both MRI and fluorescence imaging of living cells.",
keywords = "Carbon dots, dysprosium, bimodal nanoprobes, fluorescence, magnetic resonance imaging MRI",
author = "Atabaev, {Timur Sh} and Zhonglie Piao and Anara Molkenova",
year = "2018",
month = "5",
day = "18",
doi = "10.3390/jfb9020035",
language = "English",
volume = "9",
journal = "Journal of Functional Biomaterials",
issn = "2079-4983",
publisher = "MDPI AG",
number = "2",

}

TY - JOUR

T1 - Carbon Dots Doped with Dysprosium: A Bimodal Nanoprobe for MRI and Fluorescence Imaging

AU - Atabaev, Timur Sh

AU - Piao, Zhonglie

AU - Molkenova, Anara

PY - 2018/5/18

Y1 - 2018/5/18

N2 - In recent years, functional nanoprobes with multiple imaging modalities have become an emerging field of biomedical research. In this preliminary study, we utilized a facile hydrothermal method for the preparation of magneto-fluorescent bimodal carbon dots doped with dysprosium (Dy-CDs). The prepared Dy-CDs have shown a good colloidal stability in a water solution and strong blue⁻green fluorescence, with a maximum at 452 nm. In addition, the excellent transverse relaxivity of the prepared Dy-CDs (r₂ = 7.42 ± 0.07 mM-1s-1) makes them also suitable for T₂-weighted magnetic resonance imaging (MRI). Thus, synthesized Dy-CDs could be potentially utilized for both MRI and fluorescence imaging of living cells.

AB - In recent years, functional nanoprobes with multiple imaging modalities have become an emerging field of biomedical research. In this preliminary study, we utilized a facile hydrothermal method for the preparation of magneto-fluorescent bimodal carbon dots doped with dysprosium (Dy-CDs). The prepared Dy-CDs have shown a good colloidal stability in a water solution and strong blue⁻green fluorescence, with a maximum at 452 nm. In addition, the excellent transverse relaxivity of the prepared Dy-CDs (r₂ = 7.42 ± 0.07 mM-1s-1) makes them also suitable for T₂-weighted magnetic resonance imaging (MRI). Thus, synthesized Dy-CDs could be potentially utilized for both MRI and fluorescence imaging of living cells.

KW - Carbon dots

KW - dysprosium

KW - bimodal nanoprobes

KW - fluorescence

KW - magnetic resonance imaging MRI

U2 - 10.3390/jfb9020035

DO - 10.3390/jfb9020035

M3 - Article

VL - 9

JO - Journal of Functional Biomaterials

JF - Journal of Functional Biomaterials

SN - 2079-4983

IS - 2

M1 - 35

ER -