Abstract
The present study attempted to synthesize carbon quantum dots (CQDs) through Aldol polymerization reaction, wherein acetone was used as the carbon source. A nano composite CQDs/Ag2S/CS was developed by loading as prepared CQDs and Ag2S nanoparticles on a chitosan substrate (CS). An in-situation growth of nanocomposites was adopted to study their antibacterial properties. Staphylococcus aureus (Gram-positive), Escherichia coli (Gram-negative) and methicillin-resistant Staphylococcus aureus were selected as the model bacteria. The CQDs/Ag2S/CS nanocomposites exhibited excellent inhibition not only against common pathogenic bacteria, but also those well-known drug-resistant bacteria. Moreover, compared to traditional antibiotics, the as prepared nanocomposites in the present work do not likely cause bacterial drug resistance, which make them a potential candidate for a new type of clinically applicable antibiotics.
| Original language | English |
|---|---|
| Article number | 111456 |
| Journal | Journal of Inorganic Biochemistry |
| Volume | 220 |
| DOIs | |
| Publication status | Published - Jul 2021 |
Funding
This work was supported by the National Nature Science Foundations of China (Grants No. 21867015 , 22065021), the Province Nature Science Foundations of Gansu (Grants No. 20JR5RA453 ) and Hongliu Outstanding Youth Teacher Cultivate Project of Lanzhou University of Technology.
Keywords
- AgS
- Antibacterial agent
- Carbon quantum dots
- Chitosan
- Nanocomposites
- Resistant bacteria
ASJC Scopus subject areas
- Biochemistry
- Inorganic Chemistry
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