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Carbon quantum dots modified Ag2S/CS nanocomposite as effective antibacterial agents

  • Xiang Gao
  • , Hongxia Li
  • , Xiaohui Niu
  • , Deyi Zhang
  • , Yi Wang
  • , Haiyan Fan
  • , Kunjie Wang
  • Lanzhou University of Technology

Research output: Contribution to journalReview articlepeer-review

Abstract

The present study attempted to synthesize carbon quantum dots (CQDs) through Aldol polymerization reaction, wherein acetone was used as the carbon source. A nano composite CQDs/Ag2S/CS was developed by loading as prepared CQDs and Ag2S nanoparticles on a chitosan substrate (CS). An in-situation growth of nanocomposites was adopted to study their antibacterial properties. Staphylococcus aureus (Gram-positive), Escherichia coli (Gram-negative) and methicillin-resistant Staphylococcus aureus were selected as the model bacteria. The CQDs/Ag2S/CS nanocomposites exhibited excellent inhibition not only against common pathogenic bacteria, but also those well-known drug-resistant bacteria. Moreover, compared to traditional antibiotics, the as prepared nanocomposites in the present work do not likely cause bacterial drug resistance, which make them a potential candidate for a new type of clinically applicable antibiotics.

Original languageEnglish
Article number111456
JournalJournal of Inorganic Biochemistry
Volume220
DOIs
Publication statusPublished - Jul 2021

Funding

This work was supported by the National Nature Science Foundations of China (Grants No. 21867015 , 22065021), the Province Nature Science Foundations of Gansu (Grants No. 20JR5RA453 ) and Hongliu Outstanding Youth Teacher Cultivate Project of Lanzhou University of Technology.

Keywords

  • AgS
  • Antibacterial agent
  • Carbon quantum dots
  • Chitosan
  • Nanocomposites
  • Resistant bacteria

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry

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