L'interruzione CD4+ guidata della terapia antiretrovirale dell'infezione da HIV

Translated title of the contribution: CD4+ guided interruption HAART in HIV patients

Dario Antolini, Massimiliano Lanzafame, Emanuela Lattuada, Sandro Vento, Ercole Concia

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We have evaluated CD4+-guided HAART interruption in 46 HIV+ patients with CD4+>500/μl and viral load undetectable since at least 3 years. This strategy resulted effective in a long mean period of treatment interruption (18 months) and safe. In fact during the follow up period we didn't observed any case of death or opportunistic infection. Reintroduction of HAART was caused by: CD4+ fall under 200/μl (6 cases), acute retroviral syndrome (4), individual choice (2), asymptomatic thrombocytopenia (1), peripheral neuropathy (1), pregnancy (1). A low CD4+ nadir level was correlated to a short treatment interruption period.

Translated title of the contributionCD4+ guided interruption HAART in HIV patients
Original languageItalian
Pages (from-to)501-505
Number of pages5
JournalRecenti Progressi in Medicina
Volume98
Issue number10
Publication statusPublished - Oct 1 2007

Keywords

  • HAART
  • HIV
  • Lymphocytes T CD4+
  • Structured HAART interruption

ASJC Scopus subject areas

  • Medicine(all)

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