Childhood cancers: What is a possible role of infectious agents?

Kenneth Alibek, Assel Mussabekova, Ainur Kakpenova, Assem Duisembekova, Yeldar Baiken, Bauyrzhan Aituov, Nargis Karatayeva, Samal Zhussupbekova

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed.

Original languageEnglish
Article number48
JournalInfectious Agents and Cancer
Volume8
Issue number1
DOIs
Publication statusPublished - Dec 10 2013

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Keywords

  • CNS
  • Childhood cancer
  • Herpesviruses
  • Infection
  • Leukemia
  • Lymphoma
  • Papillomaviruses
  • Polyomaviruses

ASJC Scopus subject areas

  • Epidemiology
  • Oncology
  • Infectious Diseases
  • Cancer Research

Cite this

Alibek, K., Mussabekova, A., Kakpenova, A., Duisembekova, A., Baiken, Y., Aituov, B., Karatayeva, N., & Zhussupbekova, S. (2013). Childhood cancers: What is a possible role of infectious agents? Infectious Agents and Cancer, 8(1), [48]. https://doi.org/10.1186/1750-9378-8-48