Childhood cancers

What is a possible role of infectious agents?

Kenneth Alibek, Assel Mussabekova, Ainur Kakpenova, Assem Duisembekova, Yeldar Baiken, Bauyrzhan Aituov, Nargis Karatayeva, Samal Zhussupbekova

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed.

Original languageEnglish
Article number48
JournalInfectious Agents and Cancer
Volume8
Issue number1
DOIs
Publication statusPublished - Dec 10 2013

Fingerprint

Papillomaviridae
Neoplasms
Polyomavirus
Herpesviridae
Infection
Carcinogenesis

Keywords

  • Childhood cancer
  • CNS
  • Herpesviruses
  • Infection
  • Leukemia
  • Lymphoma
  • Papillomaviruses
  • Polyomaviruses

ASJC Scopus subject areas

  • Infectious Diseases
  • Oncology
  • Epidemiology
  • Cancer Research

Cite this

Childhood cancers : What is a possible role of infectious agents? / Alibek, Kenneth; Mussabekova, Assel; Kakpenova, Ainur; Duisembekova, Assem; Baiken, Yeldar; Aituov, Bauyrzhan; Karatayeva, Nargis; Zhussupbekova, Samal.

In: Infectious Agents and Cancer, Vol. 8, No. 1, 48, 10.12.2013.

Research output: Contribution to journalArticle

Alibek, K, Mussabekova, A, Kakpenova, A, Duisembekova, A, Baiken, Y, Aituov, B, Karatayeva, N & Zhussupbekova, S 2013, 'Childhood cancers: What is a possible role of infectious agents?', Infectious Agents and Cancer, vol. 8, no. 1, 48. https://doi.org/10.1186/1750-9378-8-48
Alibek, Kenneth ; Mussabekova, Assel ; Kakpenova, Ainur ; Duisembekova, Assem ; Baiken, Yeldar ; Aituov, Bauyrzhan ; Karatayeva, Nargis ; Zhussupbekova, Samal. / Childhood cancers : What is a possible role of infectious agents?. In: Infectious Agents and Cancer. 2013 ; Vol. 8, No. 1.
@article{a6cf7a9abb0e4aa3926cf5c7e447d34e,
title = "Childhood cancers: What is a possible role of infectious agents?",
abstract = "The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed.",
keywords = "Childhood cancer, CNS, Herpesviruses, Infection, Leukemia, Lymphoma, Papillomaviruses, Polyomaviruses",
author = "Kenneth Alibek and Assel Mussabekova and Ainur Kakpenova and Assem Duisembekova and Yeldar Baiken and Bauyrzhan Aituov and Nargis Karatayeva and Samal Zhussupbekova",
year = "2013",
month = "12",
day = "10",
doi = "10.1186/1750-9378-8-48",
language = "English",
volume = "8",
journal = "Infectious Agents and Cancer",
issn = "1750-9378",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Childhood cancers

T2 - What is a possible role of infectious agents?

AU - Alibek, Kenneth

AU - Mussabekova, Assel

AU - Kakpenova, Ainur

AU - Duisembekova, Assem

AU - Baiken, Yeldar

AU - Aituov, Bauyrzhan

AU - Karatayeva, Nargis

AU - Zhussupbekova, Samal

PY - 2013/12/10

Y1 - 2013/12/10

N2 - The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed.

AB - The etiology of childhood cancers has been studied for more than 40 years. However, most if not all cancers occurring in children are attributed to unknown causes. This review is focused on the role of infections in cancer development and progression in children. The main infectious agents include human herpesviruses, polyoma viruses, and human papilloma viruses. It is known that infections can lead to carcinogenesis through various mechanisms, and most likely act in addition to genetic and environmental factors. Given the importance of the infectious etiology of childhood cancers, clinical implications and possible prevention strategies are discussed.

KW - Childhood cancer

KW - CNS

KW - Herpesviruses

KW - Infection

KW - Leukemia

KW - Lymphoma

KW - Papillomaviruses

KW - Polyomaviruses

UR - http://www.scopus.com/inward/record.url?scp=84889801876&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84889801876&partnerID=8YFLogxK

U2 - 10.1186/1750-9378-8-48

DO - 10.1186/1750-9378-8-48

M3 - Article

VL - 8

JO - Infectious Agents and Cancer

JF - Infectious Agents and Cancer

SN - 1750-9378

IS - 1

M1 - 48

ER -