Clinical Equipoise and Moral Leeway: An Epistemological Stance

Ahti-Veikko Pietarinen, Daniele Chiffi

Research output: Contribution to journalArticle

Abstract

Clinical equipoise (CE) has been proposed as an ethical principle relating uncertainty and moral leeway in clinical research. Although CE has traditionally been indicated as a necessary condition for a morally justified introduction of a new RCT, questions related to the interpretation of this principle remain woefully open. Recent proposals to rehabilitate CE have divided the bioethical community on its ethical merits. A new argument is presented here to illustrate epistemological difficulties in justifying CE as a principle to connect uncertainty and moral leeway in clinical research ethics. This argument is based on the methodology of hypothetical retrospection (HR), uncertainty transduction (UT),
and a criticism of implicitly assuming the principle of indifference that can distort
received interpretations of CE
Original languageEnglish
JournalTopoi
Publication statusAccepted/In press - 2017

Fingerprint Dive into the research topics of 'Clinical Equipoise and Moral Leeway: An Epistemological Stance'. Together they form a unique fingerprint.

  • Cite this