Abstract
We report the case of a 9-year-old Senegalese girl with co-occurring wild-type (HBeAg-positive) chronic hepatitis B and antinuclear antibody-positive autoimmune hepatitis. Her HLA haplotype was A1, B8, DRB1*04, DQB1*02. Steriod and lamivudine therapy led to biochemical remission, and reactivation occurred when the patient stopped steroids. Persistent HBV infection due to wild-type virus (likely acquired vertically or early in life, as the mother was HBsAg positive) may have acted as a trigger for autoimmune hepatitis in this young girl.
| Original language | English |
|---|---|
| Pages (from-to) | 927-929 |
| Number of pages | 3 |
| Journal | European Journal of Gastroenterology and Hepatology |
| Volume | 18 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 1 2006 |
Keywords
- Autoimmune hepatitis
- Chronic hepatitis
- Hepatitis B
ASJC Scopus subject areas
- Hepatology
- Gastroenterology
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Cite this
Nobili, V., Marcellini, M., Devito, R., Comparcola, D., & Vento, S. (2006). Co-occurrence of chronic hepatitis B virus infection and autoimmune hepatitis in a young Senegalese girl. European Journal of Gastroenterology and Hepatology, 18(8), 927-929. https://doi.org/10.1097/00042737-200608000-00021