Abstract
Immunohistological methods were used to investigate the presence of carcinoembryonic antigen, β1 pregnancy specific glycoprotein, β subunit of human chorionic gonadotrophin, human placental lactogen, calcitonin, and keratin in formalin fixed tissue from 29 malignant mesotheliomas and 27 pulmonary adenocarcinomas. Malignant mesotheliomas were negative for tumour markers except for the β subunit of human chorionic gonadotrophin and keratin, one and 13 cases respectively being positive for these. Pulmonary adenocarcinomas, however, were frequently positive for tumour markers - namely, carcinoembryonic antigen (24), β1 pregnancy specific glycoprotein (23), β subunit of human chorionic gonadotrophin (8), human placental lactogen (2), calcitonin (3), and keratin (12). The presence of carcinoembryonic antigen and β1 pregnancy specific glycoprotein within an intrathoracic tumour is strong evidence against its being of mesothelial origin.
| Original language | English |
|---|---|
| Pages (from-to) | 91-95 |
| Number of pages | 5 |
| Journal | Thorax |
| Volume | 40 |
| Issue number | 2 |
| Publication status | Published - 1985 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Comparison of tumour markers in malignant mesothelioma and pulmonary adenocarcinoma. / Gibbs, A. R.; Harach, R.; Wagner, J. C.; Jasani, B.
In: Thorax, Vol. 40, No. 2, 1985, p. 91-95.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of tumour markers in malignant mesothelioma and pulmonary adenocarcinoma
AU - Gibbs, A. R.
AU - Harach, R.
AU - Wagner, J. C.
AU - Jasani, B.
PY - 1985
Y1 - 1985
N2 - Immunohistological methods were used to investigate the presence of carcinoembryonic antigen, β1 pregnancy specific glycoprotein, β subunit of human chorionic gonadotrophin, human placental lactogen, calcitonin, and keratin in formalin fixed tissue from 29 malignant mesotheliomas and 27 pulmonary adenocarcinomas. Malignant mesotheliomas were negative for tumour markers except for the β subunit of human chorionic gonadotrophin and keratin, one and 13 cases respectively being positive for these. Pulmonary adenocarcinomas, however, were frequently positive for tumour markers - namely, carcinoembryonic antigen (24), β1 pregnancy specific glycoprotein (23), β subunit of human chorionic gonadotrophin (8), human placental lactogen (2), calcitonin (3), and keratin (12). The presence of carcinoembryonic antigen and β1 pregnancy specific glycoprotein within an intrathoracic tumour is strong evidence against its being of mesothelial origin.
AB - Immunohistological methods were used to investigate the presence of carcinoembryonic antigen, β1 pregnancy specific glycoprotein, β subunit of human chorionic gonadotrophin, human placental lactogen, calcitonin, and keratin in formalin fixed tissue from 29 malignant mesotheliomas and 27 pulmonary adenocarcinomas. Malignant mesotheliomas were negative for tumour markers except for the β subunit of human chorionic gonadotrophin and keratin, one and 13 cases respectively being positive for these. Pulmonary adenocarcinomas, however, were frequently positive for tumour markers - namely, carcinoembryonic antigen (24), β1 pregnancy specific glycoprotein (23), β subunit of human chorionic gonadotrophin (8), human placental lactogen (2), calcitonin (3), and keratin (12). The presence of carcinoembryonic antigen and β1 pregnancy specific glycoprotein within an intrathoracic tumour is strong evidence against its being of mesothelial origin.
UR - http://www.scopus.com/inward/record.url?scp=0021990686&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021990686&partnerID=8YFLogxK
M3 - Article
VL - 40
SP - 91
EP - 95
JO - Thorax
JF - Thorax
SN - 0040-6376
IS - 2
ER -