Comprehensive Study of Ni Nanotubes for Bioapplications: From Synthesis to Payloads Attaching

A. L. Kozlovskiy, I. V. Korolkov, G. Kalkabay, M. A. Ibragimova, A. D. Ibrayeva, M. V. Zdorovets, V. S. Mikulich, D. V. Yakimchuk, A. E. Shumskaya, E. Yu Kaniukov

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Due to the Ni nanotubes' shape anisotropy, low specific density, large specific surface, and uniform magnetic field, they have been offered as carriers for targeted delivery of drug or protein and the process of their formation from synthesis stage to the stage of surface modification and protein attaching has been demonstrated. Some steps to hasten their biomedical application have been applied. First, to have full control over the carrier dimensions and structure parameters, electrodeposition method in pores of polyethylene terephthalate template has been applied. Second, to understand the scope of Ni nanostructures application, their degradation in media with different acidity has been studied. Third, to improve the biocompatibility and to make payloads attachment possible, nanotubes surface modification with organosilicon compound has been carried out. At last, the scheme of protein attaching to the nanostructure surface has been developed and the binding process was demonstrated as an example of the bovine serum albumin.

Original languageEnglish
Article number3060972
JournalJournal of Nanomaterials
Volume2017
DOIs
Publication statusPublished - Jan 1 2017
Externally publishedYes

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Nanotubes
Proteins
Surface treatment
Nanostructures
Organosilicon Compounds
Polyethylene Terephthalates
Bovine Serum Albumin
Biocompatibility
Electrodeposition
Acidity
Density (specific gravity)
Polyethylene terephthalates
Anisotropy
Magnetic fields
Degradation
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Kozlovskiy, A. L., Korolkov, I. V., Kalkabay, G., Ibragimova, M. A., Ibrayeva, A. D., Zdorovets, M. V., ... Kaniukov, E. Y. (2017). Comprehensive Study of Ni Nanotubes for Bioapplications: From Synthesis to Payloads Attaching. Journal of Nanomaterials, 2017, [3060972]. https://doi.org/10.1155/2017/3060972

Comprehensive Study of Ni Nanotubes for Bioapplications : From Synthesis to Payloads Attaching. / Kozlovskiy, A. L.; Korolkov, I. V.; Kalkabay, G.; Ibragimova, M. A.; Ibrayeva, A. D.; Zdorovets, M. V.; Mikulich, V. S.; Yakimchuk, D. V.; Shumskaya, A. E.; Kaniukov, E. Yu.

In: Journal of Nanomaterials, Vol. 2017, 3060972, 01.01.2017.

Research output: Contribution to journalArticle

Kozlovskiy, AL, Korolkov, IV, Kalkabay, G, Ibragimova, MA, Ibrayeva, AD, Zdorovets, MV, Mikulich, VS, Yakimchuk, DV, Shumskaya, AE & Kaniukov, EY 2017, 'Comprehensive Study of Ni Nanotubes for Bioapplications: From Synthesis to Payloads Attaching', Journal of Nanomaterials, vol. 2017, 3060972. https://doi.org/10.1155/2017/3060972
Kozlovskiy AL, Korolkov IV, Kalkabay G, Ibragimova MA, Ibrayeva AD, Zdorovets MV et al. Comprehensive Study of Ni Nanotubes for Bioapplications: From Synthesis to Payloads Attaching. Journal of Nanomaterials. 2017 Jan 1;2017. 3060972. https://doi.org/10.1155/2017/3060972
Kozlovskiy, A. L. ; Korolkov, I. V. ; Kalkabay, G. ; Ibragimova, M. A. ; Ibrayeva, A. D. ; Zdorovets, M. V. ; Mikulich, V. S. ; Yakimchuk, D. V. ; Shumskaya, A. E. ; Kaniukov, E. Yu. / Comprehensive Study of Ni Nanotubes for Bioapplications : From Synthesis to Payloads Attaching. In: Journal of Nanomaterials. 2017 ; Vol. 2017.
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