Computational tools for the study of allergens

V. Brusic, N. Petrovsky, S. M. Gendel, M. Millot, O. Gigonzac, S. J. Stelman

Research output: Contribution to journalReview article

42 Citations (Scopus)

Abstract

Allergy is a major cause of morbidity worldwide. The number of characterized allergens and related information is increasing rapidly creating demands for advanced information storage, retrieval and analysis. Bioinformatics provides useful tools for analysing allergens and these are complementary to traditional laboratory techniques for the study of allergens. Specific applications include structural analysis of allergens, identification of B- and T-cell epitopes, assessment of allergenicity and cross-reactivity, and genome analysis. In this paper, the most important bioinformatic tools and methods with relevance to the study of allergy have been reviewed.

Original languageEnglish
Pages (from-to)1083-1092
Number of pages10
JournalAllergy: European Journal of Allergy and Clinical Immunology
Volume58
Issue number11
DOIs
Publication statusPublished - Nov 1 2003

Keywords

  • Allergen
  • Molecular modelling
  • Prediction of allergenicity
  • Prediction of cross-reactivity
  • Sequence analysis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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    Brusic, V., Petrovsky, N., Gendel, S. M., Millot, M., Gigonzac, O., & Stelman, S. J. (2003). Computational tools for the study of allergens. Allergy: European Journal of Allergy and Clinical Immunology, 58(11), 1083-1092. https://doi.org/10.1034/j.1398-9995.2003.00224.x