Computational vaccinology and the ICoVax 2012 workshop.

Yongqun He, Zhiwei Cao, Anne S. De Groot, Vladimir Brusic, Christian Schönbach, Nikolai Petrovsky

Research output: Contribution to journalArticle

Abstract

Computational vaccinology or vaccine informatics is an interdisciplinary field that addresses scientific and clinical questions in vaccinology using computational and informatics approaches. Computational vaccinology overlaps with many other fields such as immunoinformatics, reverse vaccinology, postlicensure vaccine research, vaccinomics, literature mining, and systems vaccinology. The second ISV Pre-conference Computational Vaccinology Workshop (ICoVax 2012) was held on October 13, 2013 in Shanghai, China. A number of topics were presented in the workshop, including allergen predictions, prediction of linear T cell epitopes and functional conformational epitopes, prediction of protein-ligand binding regions, vaccine design using reverse vaccinology, and case studies in computational vaccinology. Although a significant progress has been made to date, a number of challenges still exist in the field. This Editorial provides a list of major challenges for the future of computational vaccinology and identifies developing themes that will expand and evolve over the next few years.

Original languageEnglish
JournalBMC Bioinformatics
Volume14 Suppl 4
DOIs
Publication statusPublished - 2013
Externally publishedYes

Fingerprint

Vaccines
Epitopes
Informatics
Education
Vaccine
Allergens
T-Lymphocyte Epitopes
T-cells
Protein Binding
Reverse
Prediction
China
Ligands
Proteins
Research
Expand
Overlap
Mining
Protein

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Applied Mathematics
  • Structural Biology

Cite this

Computational vaccinology and the ICoVax 2012 workshop. / He, Yongqun; Cao, Zhiwei; De Groot, Anne S.; Brusic, Vladimir; Schönbach, Christian; Petrovsky, Nikolai.

In: BMC Bioinformatics, Vol. 14 Suppl 4, 2013.

Research output: Contribution to journalArticle

He, Yongqun ; Cao, Zhiwei ; De Groot, Anne S. ; Brusic, Vladimir ; Schönbach, Christian ; Petrovsky, Nikolai. / Computational vaccinology and the ICoVax 2012 workshop. In: BMC Bioinformatics. 2013 ; Vol. 14 Suppl 4.
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