Content of HSP70 in rats with hereditary stress-induced arterial hypertension

G. V. Petrova, V. A. Adarichev, A. A. Krivenko, G. S. Dymshits, A. L. Markel', G. S. Yakobson

Research output: Contribution to journalArticlepeer-review

Abstract

Sensitivity of normotensive Wistar rats and NISAG rats (with hereditary arterial hypertension) to heat stress is compared at the organism and cell levels. High temperature sensitivity of NISAG rats correlates with a low content of the main heat shock protein HSP70. This relationship can serve as a biochemical marker of predisposition to arterial hypertension.

Original languageEnglish
Pages (from-to)773-775
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume124
Issue number2
DOIs
Publication statusPublished - Aug 1997

Keywords

  • Arterial hypertension
  • Heat shock proteins
  • Restriction fragment length polymorphism analysis
  • Thermosensitivity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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