Cytoplasmic antineutrophil cytoplasmic antibody-positive vasculitis associated with ulcerative colitis

Andrew Weir, Simon D. Taylor-Robinson, Simon Poole, Massimo Pignatelli, Julian F R Walters, John Calam

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Abstract

The case of a man with poorly controlled ulcerative colitis, who developed a cytoplasmic antineutrophil cytoplasmic antibody-positive systemic vasculitis, causing small bowel infarction is reported. Antineutrophil cytoplasmic antibodies occur in 50-70% of patients with ulcerative colitis, but are usually of the perinuclear or atypical pattern; the cytoplasmic pattern seen in this case is indicative of systemic vasculitis. A variety of vasculitic diseases have been reported as occurring rarely with ulcerative colitis, but this report is the first description of a cytoplasmic antineutrophil cytoplasmic antibody-positive vasculitis with this association.

Original languageEnglish
Pages (from-to)506-508
Number of pages3
JournalAmerican Journal of Gastroenterology
Volume92
Issue number3
Publication statusPublished - Mar 1 1997
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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    Weir, A., Taylor-Robinson, S. D., Poole, S., Pignatelli, M., Walters, J. F. R., & Calam, J. (1997). Cytoplasmic antineutrophil cytoplasmic antibody-positive vasculitis associated with ulcerative colitis. American Journal of Gastroenterology, 92(3), 506-508.