Abstract
Increased demand of environment protection encouraged scientists to design products and processes that minimize the use and generation of hazardous substances. This work presents comprehensive result of large-scale fabrication and investigation of red-to-green tunable submicron spherical yttria particles codoped with low concentrations of Eu+3 and Tb+3. The color emission of synthesized particles can be precisely tuned from red to green by simple variation of Tb/Eu ratio and excitation wavelength. The Tb/Eu-codoped Y2O3 particles did not adversely affect the viability of L-929 fibroblastic cells at concentrations less than 62.5 ppm. Through internalization and wide distribution inside the cells, Tb/Eu codoped Y 2O3 particles with intense bright green or red fluorescence rendered cell imaging to be possible. The high brightness, excellent stability, low-toxicity, and imaging capability along with fine color-tunability of synthesized particles enable to find promising application in various areas.
Original language | English |
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Pages (from-to) | 2287-2294 |
Number of pages | 8 |
Journal | Journal of Biomedical Materials Research - Part A |
Volume | 100 A |
Issue number | 9 |
DOIs | |
Publication status | Published - Sep 2012 |
Externally published | Yes |
Keywords
- cell imaging
- cytotoxicity
- doping
- luminescence
- YO particles
ASJC Scopus subject areas
- Biomedical Engineering
- Biomaterials
- Ceramics and Composites
- Metals and Alloys