Dendrimer nanocomposites as multifunctional X-ray contrast agents

Teyeb Ould Ely; Manju Sharma; Wojciech Lesniak; Donald L. Klippenstein; Barbara A. Foster; Lajos P. Balogh

Dendrimer nanocomposites as multifunctional X-ray contrast agents

Teyeb Ould Ely, Manju Sharma, Wojciech Lesniak, Donald L. Klippenstein, Barbara A. Foster, Lajos P. Balogh

Department of Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

We synthesized dendrimer composite nanoparticles and investigated their potential for traditional X-ray imaging and Computed Tomography (CT). These new X-ray contrast agents show better contrast compared to traditional iodine-based contrast, agents, and are expected to clear from the blood much slower than commercial agents, permitting longer imaging times. We have also investigated their safety profile in terms of viscosity and osmotic pressure.

Original language	English
Title of host publication	Quantum-Dot and Nanoparticle Bioconjugates-Tools for Sensing and Biomedical Imaging
Pages	36-42
Number of pages	7
Publication status	Published - Dec 1 2008
Event	2007 MRS Fall Meeting - Boston, MA, United States Duration: Nov 26 2007 → Nov 30 2007

Publication series

Name	Materials Research Society Symposium Proceedings
Volume	1064
ISSN (Print)	0272-9172

Other

Other	2007 MRS Fall Meeting
Country	United States
City	Boston, MA
Period	11/26/07 → 11/30/07

ASJC Scopus subject areas

Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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Dendrimer nanocomposites as multifunctional X-ray contrast agents. / Ely, Teyeb Ould; Sharma, Manju; Lesniak, Wojciech; Klippenstein, Donald L.; Foster, Barbara A.; Balogh, Lajos P.

Quantum-Dot and Nanoparticle Bioconjugates-Tools for Sensing and Biomedical Imaging. 2008. p. 36-42 (Materials Research Society Symposium Proceedings; Vol. 1064).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AU - Foster, Barbara A.

AU - Balogh, Lajos P.

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AB - We synthesized dendrimer composite nanoparticles and investigated their potential for traditional X-ray imaging and Computed Tomography (CT). These new X-ray contrast agents show better contrast compared to traditional iodine-based contrast, agents, and are expected to clear from the blood much slower than commercial agents, permitting longer imaging times. We have also investigated their safety profile in terms of viscosity and osmotic pressure.

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