EEG source imaging in partial epilepsy in comparison with presurgical evaluation and magnetoencephalography

Chae Jung Park, Ji Hye Seo, Daeyoung Kim, Berdakh Abibullaev, Hyukchan Kwon, Yong Ho Lee, Min Young Kim, Kyung Min An, Kiwoong Kim, Jeong Sik Kim, Eun Yeon Joo, Seung Bong Hong

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background and Purpose: The aim of this study was to determine the usefulness of three-dimensional (3D) scalp EEG source imaging (ESI) in partial epilepsy in comparison with the results of presurgical evaluation, magnetoencephalography (MEG), and electrocorticography (ECoG).Methods: The epilepsy syndrome of 27 partial epilepsy patients was determined by presurgical evaluations. EEG recordings were made using 70 scalp electrodes, and the 3D coordinates of the electrodes were digitized. ESI images of individual and averaged spikes were analyzed by Curry software with a boundary element method. MEG and ECoG were performed in 23 and 9 patients, respectively.Results: ESI and MEG source imaging (MSI) results were well concordant with the results of presurgical evaluations (in 96.3% and 100% cases for ESI and MSI, respectively) at the lobar level. However, there were no spikes in the MEG recordings of three patients. The ESI results were well concordant with MSI results in 90.0% of cases. Compared to ECoG, the ESI results tended to be localized deeper than the cortex, whereas the MSI results were generally localized on the cortical surface. ESI was well concordant with ECoG in 8 of 9 (88.9%) cases, and MSI was also well concordant with ECoG in 4 of 5 (80.0%) cases. The EEG single dipoles in one patient with mesial temporal lobe epilepsy were tightly clustered with the averaged dipole when a 3 Hz high-pass filter was used.Conclusions: The ESI results were well concordant with the results of the presurgical evaluation, MSI, and ECoG. The ESI analysis was found to be useful for localizing the seizure focus and is recommended for the presurgical evaluation of intractable epilepsy patients.

Original languageEnglish
Pages (from-to)319-330
Number of pages12
JournalJournal of Clinical Neurology (Korea)
Volume11
Issue number4
DOIs
Publication statusPublished - Oct 1 2015
Externally publishedYes

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Magnetoencephalography
Partial Epilepsy
Electroencephalography
Scalp
Electrodes
Insulator Elements
Temporal Lobe Epilepsy
Electrocorticography
Epilepsy
Seizures
Software

Keywords

  • EEG source imaging
  • Epilepsy surgery
  • MEG source imaging
  • Partial epilepsy
  • Presurgical evaluation
  • Source localization

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

EEG source imaging in partial epilepsy in comparison with presurgical evaluation and magnetoencephalography. / Park, Chae Jung; Seo, Ji Hye; Kim, Daeyoung; Abibullaev, Berdakh; Kwon, Hyukchan; Lee, Yong Ho; Kim, Min Young; An, Kyung Min; Kim, Kiwoong; Kim, Jeong Sik; Joo, Eun Yeon; Hong, Seung Bong.

In: Journal of Clinical Neurology (Korea), Vol. 11, No. 4, 01.10.2015, p. 319-330.

Research output: Contribution to journalArticle

Park, CJ, Seo, JH, Kim, D, Abibullaev, B, Kwon, H, Lee, YH, Kim, MY, An, KM, Kim, K, Kim, JS, Joo, EY & Hong, SB 2015, 'EEG source imaging in partial epilepsy in comparison with presurgical evaluation and magnetoencephalography', Journal of Clinical Neurology (Korea), vol. 11, no. 4, pp. 319-330. https://doi.org/10.3988/jcn.2015.11.4.319
Park, Chae Jung ; Seo, Ji Hye ; Kim, Daeyoung ; Abibullaev, Berdakh ; Kwon, Hyukchan ; Lee, Yong Ho ; Kim, Min Young ; An, Kyung Min ; Kim, Kiwoong ; Kim, Jeong Sik ; Joo, Eun Yeon ; Hong, Seung Bong. / EEG source imaging in partial epilepsy in comparison with presurgical evaluation and magnetoencephalography. In: Journal of Clinical Neurology (Korea). 2015 ; Vol. 11, No. 4. pp. 319-330.
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abstract = "Background and Purpose: The aim of this study was to determine the usefulness of three-dimensional (3D) scalp EEG source imaging (ESI) in partial epilepsy in comparison with the results of presurgical evaluation, magnetoencephalography (MEG), and electrocorticography (ECoG).Methods: The epilepsy syndrome of 27 partial epilepsy patients was determined by presurgical evaluations. EEG recordings were made using 70 scalp electrodes, and the 3D coordinates of the electrodes were digitized. ESI images of individual and averaged spikes were analyzed by Curry software with a boundary element method. MEG and ECoG were performed in 23 and 9 patients, respectively.Results: ESI and MEG source imaging (MSI) results were well concordant with the results of presurgical evaluations (in 96.3{\%} and 100{\%} cases for ESI and MSI, respectively) at the lobar level. However, there were no spikes in the MEG recordings of three patients. The ESI results were well concordant with MSI results in 90.0{\%} of cases. Compared to ECoG, the ESI results tended to be localized deeper than the cortex, whereas the MSI results were generally localized on the cortical surface. ESI was well concordant with ECoG in 8 of 9 (88.9{\%}) cases, and MSI was also well concordant with ECoG in 4 of 5 (80.0{\%}) cases. The EEG single dipoles in one patient with mesial temporal lobe epilepsy were tightly clustered with the averaged dipole when a 3 Hz high-pass filter was used.Conclusions: The ESI results were well concordant with the results of the presurgical evaluation, MSI, and ECoG. The ESI analysis was found to be useful for localizing the seizure focus and is recommended for the presurgical evaluation of intractable epilepsy patients.",
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AU - Kwon, Hyukchan

AU - Lee, Yong Ho

AU - Kim, Min Young

AU - An, Kyung Min

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