Effect of different doses of local anesthetics on outcomes in spinal anesthesia: A meta-analysis

Yerkin Abdildin, Fatima Nabidollayeva, Dmitriy Viderman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This work compares the effect of different doses of local anesthetics in spinal anesthesia on the death rate, incidences of pneumonia, urinary infection, and drug consumption like ephedrine. We conduct a statistical analysis of research studies known as meta-analysis. Data values from four studies were collected, aggregated, and compared by the sample means and sample standard deviations of the two groups of patients with 'low doses' and 'high doses' of used local anesthetics. Our analysis found that there is no statistically significant difference between the lower and higher doses of local anesthetics for spinal anesthesia in terms of death rate (the risk ratio (RR) with a 95% CI is 0.87 [0.12, 6.53]), incidences of pneumonia (RR with 95% CI is 0.93 [0.74, 1.16]), incidences of urinary infection (RR with 95% CI is 1.25 [0.16, 9.56]), and the doses of used ephedrine (SMD with 95% CI is -0.31 [-1.19, 0.56]). Findings suggest that the choice of local anesthetic dose in spinal anesthesia may not significantly impact the above-mentioned outcomes.

Original languageEnglish
Title of host publication17th IEEE International Conference on Application of Information and Communication Technologies, AICT 2023 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798350303568
DOIs
Publication statusPublished - 2023
Event17th IEEE International Conference on Application of Information and Communication Technologies, AICT 2023 - Baku, Azerbaijan
Duration: Oct 18 2023Oct 20 2023

Publication series

Name17th IEEE International Conference on Application of Information and Communication Technologies, AICT 2023 - Proceedings

Conference

Conference17th IEEE International Conference on Application of Information and Communication Technologies, AICT 2023
Country/TerritoryAzerbaijan
CityBaku
Period10/18/2310/20/23

Keywords

  • death rate
  • doses of local anesthetics
  • incidences of pneumonia and urinary infection
  • meta-analysis
  • spinal anesthesia

ASJC Scopus subject areas

  • Information Systems
  • Information Systems and Management
  • Modelling and Simulation
  • Artificial Intelligence
  • Computer Networks and Communications
  • Computer Science Applications

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