Efficacy of acitretin for porokeratosis in a child with chronic cutaneous graft versus host disease

Riccardo G. Borroni, Dimitri Poddighe, Marco Zecca, Valeria Brazzelli

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Porokeratosis is a rare disorder of epidermal keratinization that is regarded as a precancerous. Recipients of hematopoietic stem cell transplantation (HSCT) have a greater risk of skin cancer; chronic graft versus host disease (GVHD) is an additional risk factor. A 16-year-old boy who had received HSCT for acute myelogenous leukemia was referred to us for sclerodermoid chronic cutaneous GVHD. Two years later, he developed disseminated porokeratosis with a few atypical lesions. Despite cryotherapy, numerous lesions of porokeratosis recurred rapidly. Acitretin resulted in good clinical response and reduced the rate of onset of new lesions.

Original languageEnglish
Pages (from-to)148-150
Number of pages3
JournalPediatric Dermatology
Volume30
Issue number1
DOIs
Publication statusPublished - Jan 1 2013
Externally publishedYes

Fingerprint

Porokeratosis
Acitretin
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Skin
Cryotherapy
Skin Neoplasms
Acute Myeloid Leukemia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

Cite this

Efficacy of acitretin for porokeratosis in a child with chronic cutaneous graft versus host disease. / Borroni, Riccardo G.; Poddighe, Dimitri; Zecca, Marco; Brazzelli, Valeria.

In: Pediatric Dermatology, Vol. 30, No. 1, 01.01.2013, p. 148-150.

Research output: Contribution to journalArticle

Borroni, Riccardo G. ; Poddighe, Dimitri ; Zecca, Marco ; Brazzelli, Valeria. / Efficacy of acitretin for porokeratosis in a child with chronic cutaneous graft versus host disease. In: Pediatric Dermatology. 2013 ; Vol. 30, No. 1. pp. 148-150.
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