Electrochemical C-H cyanation of electron-rich (Hetero)arenes

Davit Hayrapetyan, Raja K. Rit, Markus Kratz, Kristina Tschulik, Lukas J. Gooßen

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

A straightforward method for the electrochemical C-H cyanation of arenes and heteroarenes that proceeds at room temperature in MeOH, with NaCN as the reagent in a simple, open, undivided electrochemical cell is reported. The platinum electrodes are passivated by ad-sorbed cyanide, which allows conversion of an exceptionally broad range of electron-rich substrates all the way down to dialkyl arenes. The cyanide electrolyte can be replenished with HCN, opening opportunities for salt-free industrial C-H cyanation.

Original languageEnglish
Pages (from-to)11288-11291
Number of pages4
JournalChemistry - A European Journal
Volume24
Issue number44
DOIs
Publication statusPublished - Jan 1 2018
Externally publishedYes

Keywords

  • Aromatic substitution
  • Cyanides
  • Electrochemistry
  • Synthetic methods

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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