Emergence of Circulating Recombinant Form 56-cpx in Pakistan

Uroosa Tariq; Azra Parveen; Furqana Akhtar; Faisal Mahmood; Syed Ali; Syed Hani Abidi

doi:10.1089/aid.2018.0128

Emergence of Circulating Recombinant Form 56-cpx in Pakistan

Uroosa Tariq, Azra Parveen, Furqana Akhtar, Faisal Mahmood, Syed Ali, Syed Hani Abidi

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

In Pakistan, HIV has converted from outbreak to concentrated epidemic and has also bridged into the low-risk population. The HIV epidemic in Pakistan mainly comprises subtype A. Here, we present the first case and genetic analysis of a circulating recombinant form 56-cpx in a Pakistani HIV-infected patient. Genetic analysis of the sequence indicated that Pakistani 56-cpx sequence had more drug resistance mutation than the other 56-cpx sequences available in the database.

Original language	English
Pages (from-to)	1002-1004
Number of pages	3
Journal	AIDS Research and Human Retroviruses
Volume	34
Issue number	11
DOIs	https://doi.org/10.1089/aid.2018.0128
Publication status	Published - Nov 2018

Keywords

CRF 56-cpx
HIV-1
Pakistan
drug resistance

ASJC Scopus subject areas

Immunology
Virology
Infectious Diseases

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title = "Emergence of Circulating Recombinant Form 56-cpx in Pakistan",

abstract = "In Pakistan, HIV has converted from outbreak to concentrated epidemic and has also bridged into the low-risk population. The HIV epidemic in Pakistan mainly comprises subtype A. Here, we present the first case and genetic analysis of a circulating recombinant form 56-cpx in a Pakistani HIV-infected patient. Genetic analysis of the sequence indicated that Pakistani 56-cpx sequence had more drug resistance mutation than the other 56-cpx sequences available in the database.",

keywords = "CRF 56-cpx, HIV-1, Pakistan, drug resistance",

author = "Uroosa Tariq and Azra Parveen and Furqana Akhtar and Faisal Mahmood and Syed Ali and Abidi, {Syed Hani}",

note = "Funding Information: This research was funded by Aga Khan University Seed Money (grant no. PF84/0716) and Higher Education Commission (grant no. HEC-5217).",

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AU - Tariq, Uroosa

AU - Parveen, Azra

AU - Akhtar, Furqana

AU - Mahmood, Faisal

AU - Ali, Syed

AU - Abidi, Syed Hani

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AB - In Pakistan, HIV has converted from outbreak to concentrated epidemic and has also bridged into the low-risk population. The HIV epidemic in Pakistan mainly comprises subtype A. Here, we present the first case and genetic analysis of a circulating recombinant form 56-cpx in a Pakistani HIV-infected patient. Genetic analysis of the sequence indicated that Pakistani 56-cpx sequence had more drug resistance mutation than the other 56-cpx sequences available in the database.

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KW - drug resistance

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Emergence of Circulating Recombinant Form 56-cpx in Pakistan

Abstract

Keywords

ASJC Scopus subject areas

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