Endotoxin-induced appearance of peroxidase-positive cells in the white pulp of the mouse spleen

B. Jasani, J. M. Stark

Research output: Contribution to journalArticlepeer-review

Abstract

Endotoxin (1 - 10 μg intravenously) increased the number of strongly peroxidase-positive cells in the white pulp of the mouse spleen, demonstrable by the Graham-Karnovsky technique. The increase was greatest after 10 h, the cells being found most frequently around the central vessels of the white pulp. The appearance of such cells at this critical immunological site may relate to the known adjuvant activity of endotoxin in promoting immune responses against protein antigens.

Original languageEnglish
Pages (from-to)535-539
Number of pages5
JournalImmunology
Volume39
Issue number4
Publication statusPublished - Jan 1 1980

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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